Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RRM2 |
| Enrichment Score (ES) | -0.9149569 |
| Normalized Enrichment Score (NES) | -1.7069615 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6969 | No |
| 2 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8800 | No |
| 3 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8779 | No |
| 4 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.9013 | Yes |
| 5 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34590 | -1.550 | -0.8884 | Yes |
| 6 | SMC1A | structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111] | 35041 | -1.760 | -0.8850 | Yes |
| 7 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.8731 | Yes |
| 8 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.8618 | Yes |
| 9 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35625 | -2.133 | -0.8473 | Yes |
| 10 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.8302 | Yes |
| 11 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35883 | -2.351 | -0.8138 | Yes |
| 12 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36021 | -2.474 | -0.7956 | Yes |
| 13 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.7775 | Yes |
| 14 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36254 | -2.721 | -0.7539 | Yes |
| 15 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36318 | -2.818 | -0.7307 | Yes |
| 16 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.7058 | Yes |
| 17 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36333 | -2.835 | -0.6809 | Yes |
| 18 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36438 | -2.948 | -0.6576 | Yes |
| 19 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36448 | -2.956 | -0.6316 | Yes |
| 20 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.6055 | Yes |
| 21 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36495 | -3.045 | -0.5795 | Yes |
| 22 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36533 | -3.091 | -0.5531 | Yes |
| 23 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.5260 | Yes |
| 24 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.4990 | Yes |
| 25 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.4709 | Yes |
| 26 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36620 | -3.234 | -0.4422 | Yes |
| 27 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36652 | -3.287 | -0.4140 | Yes |
| 28 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.3852 | Yes |
| 29 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.3559 | Yes |
| 30 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36797 | -3.534 | -0.3269 | Yes |
| 31 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36802 | -3.541 | -0.2956 | Yes |
| 32 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36809 | -3.551 | -0.2644 | Yes |
| 33 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.2330 | Yes |
| 34 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.2014 | Yes |
| 35 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.1696 | Yes |
| 36 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36886 | -3.735 | -0.1373 | Yes |
| 37 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.1039 | Yes |
| 38 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36957 | -3.986 | -0.0699 | Yes |
| 39 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36988 | -4.101 | -0.0343 | Yes |
| 40 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | 0.0020 | Yes |
