Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_SMC4L1 |
| Enrichment Score (ES) | -0.83161855 |
| Normalized Enrichment Score (NES) | -1.6868467 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.2419501E-4 |
| FWER p-Value | 0.002 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 886 | 1.656 | -0.0147 | No |
| 2 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 1529 | 1.129 | -0.0257 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2357 | 0.761 | -0.0438 | No |
| 4 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 2440 | 0.733 | -0.0419 | No |
| 5 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2463 | 0.725 | -0.0384 | No |
| 6 | SRSF1 | serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] | 2982 | 0.569 | -0.0492 | No |
| 7 | NUP153 | nucleoporin 153 [Source:HGNC Symbol;Acc:HGNC:8062] | 3758 | 0.402 | -0.0679 | No |
| 8 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 4300 | 0.299 | -0.0808 | No |
| 9 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5133 | 0.163 | -0.1024 | No |
| 10 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6614 | No |
| 11 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 27322 | -0.034 | -0.7017 | No |
| 12 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 28221 | -0.143 | -0.7252 | No |
| 13 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 28432 | -0.171 | -0.7299 | No |
| 14 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 28511 | -0.184 | -0.7310 | No |
| 15 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29558 | -0.319 | -0.7575 | No |
| 16 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30485 | -0.450 | -0.7800 | No |
| 17 | HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13729] | 31528 | -0.623 | -0.8047 | No |
| 18 | COPS3 | COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239] | 31971 | -0.721 | -0.8126 | No |
| 19 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32676 | -0.898 | -0.8265 | Yes |
| 20 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 32865 | -0.942 | -0.8263 | Yes |
| 21 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8224 | Yes |
| 22 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 32979 | -0.978 | -0.8185 | Yes |
| 23 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 33043 | -0.994 | -0.8146 | Yes |
| 24 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8127 | Yes |
| 25 | ANP32B | acidic nuclear phosphoprotein 32 family member B [Source:HGNC Symbol;Acc:HGNC:16677] | 33388 | -1.104 | -0.8119 | Yes |
| 26 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.8117 | Yes |
| 27 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34209 | -1.394 | -0.8195 | Yes |
| 28 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8204 | Yes |
| 29 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 34841 | -1.659 | -0.8187 | Yes |
| 30 | EXOSC8 | exosome component 8 [Source:HGNC Symbol;Acc:HGNC:17035] | 34893 | -1.685 | -0.8106 | Yes |
| 31 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.8025 | Yes |
| 32 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 35064 | -1.781 | -0.7956 | Yes |
| 33 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35070 | -1.784 | -0.7857 | Yes |
| 34 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.7792 | Yes |
| 35 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35306 | -1.922 | -0.7708 | Yes |
| 36 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35322 | -1.930 | -0.7604 | Yes |
| 37 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.7528 | Yes |
| 38 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35526 | -2.066 | -0.7429 | Yes |
| 39 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35590 | -2.112 | -0.7328 | Yes |
| 40 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.7214 | Yes |
| 41 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35629 | -2.136 | -0.7099 | Yes |
| 42 | ZWILCH | zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468] | 35645 | -2.149 | -0.6982 | Yes |
| 43 | DEK | DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768] | 35653 | -2.153 | -0.6864 | Yes |
| 44 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.6757 | Yes |
| 45 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35912 | -2.379 | -0.6676 | Yes |
| 46 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35976 | -2.431 | -0.6557 | Yes |
| 47 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.6425 | Yes |
| 48 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36006 | -2.459 | -0.6289 | Yes |
| 49 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36021 | -2.474 | -0.6155 | Yes |
| 50 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36023 | -2.475 | -0.6016 | Yes |
| 51 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 36043 | -2.495 | -0.5881 | Yes |
| 52 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36050 | -2.499 | -0.5743 | Yes |
| 53 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.5641 | Yes |
| 54 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36278 | -2.752 | -0.5499 | Yes |
| 55 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36318 | -2.818 | -0.5352 | Yes |
| 56 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.5195 | Yes |
| 57 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36416 | -2.915 | -0.5056 | Yes |
| 58 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36438 | -2.948 | -0.4896 | Yes |
| 59 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36448 | -2.956 | -0.4733 | Yes |
| 60 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.4569 | Yes |
| 61 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36495 | -3.045 | -0.4408 | Yes |
| 62 | FBXO5 | F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584] | 36501 | -3.050 | -0.4238 | Yes |
| 63 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36533 | -3.091 | -0.4073 | Yes |
| 64 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36578 | -3.169 | -0.3907 | Yes |
| 65 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.3733 | Yes |
| 66 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.3558 | Yes |
| 67 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36622 | -3.236 | -0.3377 | Yes |
| 68 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.3199 | Yes |
| 69 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.3022 | Yes |
| 70 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36690 | -3.355 | -0.2835 | Yes |
| 71 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36735 | -3.416 | -0.2656 | Yes |
| 72 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36771 | -3.483 | -0.2470 | Yes |
| 73 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36786 | -3.511 | -0.2277 | Yes |
| 74 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36802 | -3.541 | -0.2083 | Yes |
| 75 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.1887 | Yes |
| 76 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.1688 | Yes |
| 77 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.1489 | Yes |
| 78 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1286 | Yes |
| 79 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36886 | -3.735 | -0.1082 | Yes |
| 80 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36915 | -3.854 | -0.0873 | Yes |
| 81 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36946 | -3.945 | -0.0660 | Yes |
| 82 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36988 | -4.101 | -0.0441 | Yes |
| 83 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37012 | -4.172 | -0.0214 | Yes |
| 84 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | 0.0020 | Yes |
