Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_121 |
| Enrichment Score (ES) | 0.6502525 |
| Normalized Enrichment Score (NES) | 1.6314398 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07348481 |
| FWER p-Value | 0.472 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.995 | 0.0414 | Yes |
| 2 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 2 | 4.994 | 0.0829 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 8 | 4.953 | 0.1238 | Yes |
| 4 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 9 | 4.938 | 0.1648 | Yes |
| 5 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 17 | 4.860 | 0.2049 | Yes |
| 6 | VEGFC | vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682] | 30 | 4.766 | 0.2442 | Yes |
| 7 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 34 | 4.731 | 0.2833 | Yes |
| 8 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 68 | 4.313 | 0.3182 | Yes |
| 9 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 69 | 4.312 | 0.3540 | Yes |
| 10 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 84 | 4.188 | 0.3884 | Yes |
| 11 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 135 | 3.797 | 0.4185 | Yes |
| 12 | TSPAN3 | tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752] | 292 | 2.914 | 0.4385 | Yes |
| 13 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 365 | 2.656 | 0.4586 | Yes |
| 14 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 410 | 2.520 | 0.4783 | Yes |
| 15 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 440 | 2.432 | 0.4977 | Yes |
| 16 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 560 | 2.161 | 0.5124 | Yes |
| 17 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 637 | 2.010 | 0.5270 | Yes |
| 18 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 654 | 1.986 | 0.5431 | Yes |
| 19 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 698 | 1.916 | 0.5578 | Yes |
| 20 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 739 | 1.830 | 0.5719 | Yes |
| 21 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 777 | 1.779 | 0.5857 | Yes |
| 22 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 1145 | 1.391 | 0.5873 | Yes |
| 23 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 1342 | 1.239 | 0.5923 | Yes |
| 24 | ZEB1 | zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642] | 1377 | 1.219 | 0.6015 | Yes |
| 25 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 1412 | 1.197 | 0.6105 | Yes |
| 26 | HBEGF | heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] | 1460 | 1.167 | 0.6189 | Yes |
| 27 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1501 | 1.144 | 0.6273 | Yes |
| 28 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1615 | 1.080 | 0.6332 | Yes |
| 29 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 1761 | 0.996 | 0.6376 | Yes |
| 30 | MXD1 | MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] | 1862 | 0.960 | 0.6428 | Yes |
| 31 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 1880 | 0.952 | 0.6503 | Yes |
| 32 | PSPHP1 | phosphoserine phosphatase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9578] | 2869 | 0.597 | 0.6285 | No |
| 33 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 3639 | 0.424 | 0.6112 | No |
| 34 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 3735 | 0.404 | 0.6120 | No |
| 35 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 3784 | 0.397 | 0.6140 | No |
| 36 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 4079 | 0.345 | 0.6089 | No |
| 37 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 4190 | 0.320 | 0.6086 | No |
| 38 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6232 | 0.000 | 0.5534 | No |
| 39 | AREG | amphiregulin [Source:HGNC Symbol;Acc:HGNC:651] | 7142 | 0.000 | 0.5289 | No |
| 40 | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 7361 | 0.000 | 0.5230 | No |
| 41 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8653 | 0.000 | 0.4881 | No |
| 42 | GRPR | gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609] | 9869 | 0.000 | 0.4552 | No |
| 43 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10814 | 0.000 | 0.4297 | No |
| 44 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 11834 | 0.000 | 0.4022 | No |
| 45 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12398 | 0.000 | 0.3869 | No |
| 46 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12414 | 0.000 | 0.3865 | No |
| 47 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12415 | 0.000 | 0.3865 | No |
| 48 | VIP | vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693] | 13099 | 0.000 | 0.3681 | No |
| 49 | VIPR1 | vasoactive intestinal peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:12694] | 13301 | 0.000 | 0.3626 | No |
| 50 | IL15RA | interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978] | 14065 | 0.000 | 0.3420 | No |
| 51 | TACSTD2 | tumor associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:HGNC:11530] | 14383 | 0.000 | 0.3334 | No |
| 52 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15711 | 0.000 | 0.2976 | No |
| 53 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15712 | 0.000 | 0.2976 | No |
| 54 | MST1R | macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381] | 16208 | 0.000 | 0.2842 | No |
| 55 | FGA | fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661] | 16630 | 0.000 | 0.2728 | No |
| 56 | FGG | fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694] | 16631 | 0.000 | 0.2728 | No |
| 57 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16876 | 0.000 | 0.2662 | No |
| 58 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17004 | 0.000 | 0.2628 | No |
| 59 | IL3 | interleukin 3 [Source:HGNC Symbol;Acc:HGNC:6011] | 17652 | 0.000 | 0.2453 | No |
| 60 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17756 | 0.000 | 0.2425 | No |
| 61 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18898 | 0.000 | 0.2117 | No |
| 62 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19343 | 0.000 | 0.1997 | No |
| 63 | PTN | pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] | 20010 | 0.000 | 0.1817 | No |
| 64 | EDNRA | endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] | 21703 | 0.000 | 0.1359 | No |
| 65 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22072 | 0.000 | 0.1260 | No |
| 66 | CCN1 | cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654] | 22760 | 0.000 | 0.1074 | No |
| 67 | SLAMF1 | signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903] | 22794 | 0.000 | 0.1065 | No |
| 68 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 22911 | 0.000 | 0.1034 | No |
| 69 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 22912 | 0.000 | 0.1034 | No |
| 70 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24246 | 0.000 | 0.0673 | No |
| 71 | FGF4 | fibroblast growth factor 4 [Source:HGNC Symbol;Acc:HGNC:3682] | 25066 | 0.000 | 0.0452 | No |
| 72 | REG1B | regenerating family member 1 beta [Source:HGNC Symbol;Acc:HGNC:9952] | 26046 | 0.000 | 0.0187 | No |
| 73 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27294 | -0.030 | -0.0147 | No |
| 74 | CSRP2 | cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470] | 27450 | -0.053 | -0.0185 | No |
| 75 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 28156 | -0.134 | -0.0364 | No |
| 76 | EPHB4 | EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395] | 28990 | -0.244 | -0.0569 | No |
| 77 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 29032 | -0.250 | -0.0560 | No |
| 78 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 29838 | -0.357 | -0.0748 | No |
| 79 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 30014 | -0.381 | -0.0763 | No |
| 80 | FGB | fibrinogen beta chain [Source:HGNC Symbol;Acc:HGNC:3662] | 30275 | -0.419 | -0.0799 | No |
| 81 | GRN | granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601] | 30586 | -0.467 | -0.0844 | No |
| 82 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 31817 | -0.682 | -0.1120 | No |
| 83 | CRIP1 | cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360] | 33173 | -1.036 | -0.1400 | No |
| 84 | GAS6 | growth arrest specific 6 [Source:HGNC Symbol;Acc:HGNC:4168] | 33413 | -1.113 | -0.1372 | No |
| 85 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 33478 | -1.133 | -0.1296 | No |
| 86 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 33512 | -1.146 | -0.1209 | No |
| 87 | SFN | stratifin [Source:HGNC Symbol;Acc:HGNC:10773] | 33555 | -1.158 | -0.1125 | No |
| 88 | MAPRE2 | microtubule associated protein RP/EB family member 2 [Source:HGNC Symbol;Acc:HGNC:6891] | 33866 | -1.268 | -0.1103 | No |
| 89 | TGFB3 | transforming growth factor beta 3 [Source:HGNC Symbol;Acc:HGNC:11769] | 34008 | -1.314 | -0.1032 | No |
| 90 | INSIG1 | insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] | 34036 | -1.323 | -0.0930 | No |
| 91 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 34391 | -1.471 | -0.0904 | No |
| 92 | CREG1 | cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351] | 34905 | -1.690 | -0.0902 | No |
| 93 | RUNX3 | RUNX family transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473] | 35162 | -1.832 | -0.0819 | No |
| 94 | LRP1 | LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692] | 35720 | -2.206 | -0.0787 | No |
| 95 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 35979 | -2.433 | -0.0655 | No |
| 96 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 35990 | -2.443 | -0.0455 | No |
| 97 | EPS8 | epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420] | 36237 | -2.705 | -0.0297 | No |
| 98 | ZFP36L2 | ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108] | 36524 | -3.072 | -0.0119 | No |
| 99 | BCAR1 | BCAR1 scaffold protein, Cas family member [Source:HGNC Symbol;Acc:HGNC:971] | 36644 | -3.276 | 0.0121 | No |
