Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_208 |
| Enrichment Score (ES) | 0.60250944 |
| Normalized Enrichment Score (NES) | 1.5994081 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.09998007 |
| FWER p-Value | 0.598 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 8 | 4.953 | 0.0395 | Yes |
| 2 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 18 | 4.859 | 0.0783 | Yes |
| 3 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 21 | 4.831 | 0.1170 | Yes |
| 4 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 29 | 4.772 | 0.1551 | Yes |
| 5 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 31 | 4.760 | 0.1933 | Yes |
| 6 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 53 | 4.513 | 0.2290 | Yes |
| 7 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 79 | 4.215 | 0.2621 | Yes |
| 8 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 86 | 4.166 | 0.2954 | Yes |
| 9 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 104 | 4.029 | 0.3273 | Yes |
| 10 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 113 | 3.956 | 0.3588 | Yes |
| 11 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 136 | 3.791 | 0.3886 | Yes |
| 12 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 142 | 3.728 | 0.4184 | Yes |
| 13 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 176 | 3.554 | 0.4461 | Yes |
| 14 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 238 | 3.159 | 0.4698 | Yes |
| 15 | NLRC5 | NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933] | 301 | 2.873 | 0.4911 | Yes |
| 16 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 440 | 2.432 | 0.5069 | Yes |
| 17 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 542 | 2.202 | 0.5219 | Yes |
| 18 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 582 | 2.113 | 0.5378 | Yes |
| 19 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 584 | 2.105 | 0.5546 | Yes |
| 20 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 662 | 1.976 | 0.5684 | Yes |
| 21 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 701 | 1.904 | 0.5827 | Yes |
| 22 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1381 | 1.214 | 0.5740 | Yes |
| 23 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 1493 | 1.148 | 0.5803 | Yes |
| 24 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1615 | 1.080 | 0.5857 | Yes |
| 25 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1664 | 1.051 | 0.5928 | Yes |
| 26 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1840 | 0.965 | 0.5958 | Yes |
| 27 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 1915 | 0.939 | 0.6013 | Yes |
| 28 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 2172 | 0.827 | 0.6011 | Yes |
| 29 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2370 | 0.759 | 0.6018 | Yes |
| 30 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 2551 | 0.693 | 0.6025 | Yes |
| 31 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 2907 | 0.586 | 0.5976 | No |
| 32 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 3617 | 0.428 | 0.5819 | No |
| 33 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 3647 | 0.423 | 0.5845 | No |
| 34 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 3784 | 0.397 | 0.5840 | No |
| 35 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 3858 | 0.384 | 0.5851 | No |
| 36 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4225 | 0.313 | 0.5777 | No |
| 37 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 4262 | 0.304 | 0.5792 | No |
| 38 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 4378 | 0.282 | 0.5783 | No |
| 39 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 4925 | 0.194 | 0.5651 | No |
| 40 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 4979 | 0.186 | 0.5652 | No |
| 41 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 5504 | 0.109 | 0.5519 | No |
| 42 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 5581 | 0.097 | 0.5506 | No |
| 43 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 6038 | 0.028 | 0.5385 | No |
| 44 | MCU | mitochondrial calcium uniporter [Source:HGNC Symbol;Acc:HGNC:23526] | 6178 | 0.003 | 0.5347 | No |
| 45 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6254 | 0.000 | 0.5327 | No |
| 46 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6686 | 0.000 | 0.5211 | No |
| 47 | SELP | selectin P [Source:HGNC Symbol;Acc:HGNC:10721] | 7008 | 0.000 | 0.5124 | No |
| 48 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7663 | 0.000 | 0.4947 | No |
| 49 | CD200 | CD200 molecule [Source:HGNC Symbol;Acc:HGNC:7203] | 7960 | 0.000 | 0.4867 | No |
| 50 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8870 | 0.000 | 0.4621 | No |
| 51 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9725 | 0.000 | 0.4390 | No |
| 52 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9792 | 0.000 | 0.4372 | No |
| 53 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9797 | 0.000 | 0.4371 | No |
| 54 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9937 | 0.000 | 0.4333 | No |
| 55 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10420 | 0.000 | 0.4203 | No |
| 56 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10923 | 0.000 | 0.4067 | No |
| 57 | GZMA | granzyme A [Source:HGNC Symbol;Acc:HGNC:4708] | 11999 | 0.000 | 0.3776 | No |
| 58 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12065 | 0.000 | 0.3759 | No |
| 59 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12382 | 0.000 | 0.3673 | No |
| 60 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12386 | 0.000 | 0.3673 | No |
| 61 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12451 | 0.000 | 0.3655 | No |
| 62 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13363 | 0.000 | 0.3409 | No |
| 63 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13773 | 0.000 | 0.3298 | No |
| 64 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13797 | 0.000 | 0.3292 | No |
| 65 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14530 | 0.000 | 0.3094 | No |
| 66 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15593 | 0.000 | 0.2807 | No |
| 67 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15711 | 0.000 | 0.2775 | No |
| 68 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15820 | 0.000 | 0.2746 | No |
| 69 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16136 | 0.000 | 0.2661 | No |
| 70 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16165 | 0.000 | 0.2653 | No |
| 71 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16460 | 0.000 | 0.2573 | No |
| 72 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16470 | 0.000 | 0.2571 | No |
| 73 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17102 | 0.000 | 0.2400 | No |
| 74 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17721 | 0.000 | 0.2233 | No |
| 75 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18306 | 0.000 | 0.2075 | No |
| 76 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18325 | 0.000 | 0.2070 | No |
| 77 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18755 | 0.000 | 0.1954 | No |
| 78 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18775 | 0.000 | 0.1949 | No |
| 79 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18781 | 0.000 | 0.1948 | No |
| 80 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18798 | 0.000 | 0.1943 | No |
| 81 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19331 | 0.000 | 0.1800 | No |
| 82 | TCF7 | transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639] | 19695 | 0.000 | 0.1701 | No |
| 83 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20524 | 0.000 | 0.1477 | No |
| 84 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20722 | 0.000 | 0.1424 | No |
| 85 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 22205 | 0.000 | 0.1023 | No |
| 86 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22249 | 0.000 | 0.1012 | No |
| 87 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22725 | 0.000 | 0.0883 | No |
| 88 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 22816 | 0.000 | 0.0859 | No |
| 89 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 22844 | 0.000 | 0.0851 | No |
| 90 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 22911 | 0.000 | 0.0834 | No |
| 91 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 22980 | 0.000 | 0.0815 | No |
| 92 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 23128 | 0.000 | 0.0775 | No |
| 93 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23250 | 0.000 | 0.0743 | No |
| 94 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 24790 | 0.000 | 0.0326 | No |
| 95 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25202 | 0.000 | 0.0215 | No |
| 96 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25479 | 0.000 | 0.0141 | No |
| 97 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 28156 | -0.134 | -0.0573 | No |
| 98 | CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene [Source:HGNC Symbol;Acc:HGNC:2098] | 28664 | -0.203 | -0.0693 | No |
| 99 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 28981 | -0.243 | -0.0759 | No |
| 100 | ZNF292 | zinc finger protein 292 [Source:HGNC Symbol;Acc:HGNC:18410] | 29543 | -0.317 | -0.0886 | No |
| 101 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 29635 | -0.327 | -0.0884 | No |
| 102 | USP30 | ubiquitin specific peptidase 30 [Source:HGNC Symbol;Acc:HGNC:20065] | 29743 | -0.344 | -0.0885 | No |
| 103 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 30096 | -0.394 | -0.0949 | No |
| 104 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 30646 | -0.476 | -0.1059 | No |
| 105 | KCNA3 | potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221] | 30887 | -0.513 | -0.1083 | No |
| 106 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 31001 | -0.532 | -0.1071 | No |
| 107 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 31311 | -0.580 | -0.1108 | No |
| 108 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 31804 | -0.679 | -0.1187 | No |
| 109 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 31872 | -0.696 | -0.1149 | No |
| 110 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32217 | -0.779 | -0.1179 | No |
| 111 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 33420 | -1.115 | -0.1415 | No |
| 112 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33631 | -1.187 | -0.1377 | No |
| 113 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 34283 | -1.427 | -0.1438 | No |
| 114 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35032 | -1.757 | -0.1500 | No |
| 115 | S1PR1 | sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165] | 35164 | -1.833 | -0.1388 | No |
| 116 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 35748 | -2.222 | -0.1367 | No |
| 117 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35853 | -2.321 | -0.1209 | No |
| 118 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 36300 | -2.788 | -0.1106 | No |
| 119 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36387 | -2.890 | -0.0897 | No |
| 120 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36406 | -2.907 | -0.0669 | No |
| 121 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36695 | -3.366 | -0.0477 | No |
| 122 | SLC40A1 | solute carrier family 40 member 1 [Source:HGNC Symbol;Acc:HGNC:10909] | 36713 | -3.393 | -0.0209 | No |
| 123 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36921 | -3.869 | 0.0046 | No |
