Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_345 |
| Enrichment Score (ES) | 0.6725564 |
| Normalized Enrichment Score (NES) | 1.7396606 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.028416501 |
| FWER p-Value | 0.125 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 8 | 4.953 | 0.0359 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 14 | 4.897 | 0.0715 | Yes |
| 3 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 18 | 4.859 | 0.1069 | Yes |
| 4 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 21 | 4.831 | 0.1421 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 28 | 4.772 | 0.1768 | Yes |
| 6 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 53 | 4.513 | 0.2091 | Yes |
| 7 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 79 | 4.215 | 0.2392 | Yes |
| 8 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 86 | 4.166 | 0.2694 | Yes |
| 9 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 104 | 4.029 | 0.2984 | Yes |
| 10 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 113 | 3.956 | 0.3270 | Yes |
| 11 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 134 | 3.807 | 0.3542 | Yes |
| 12 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 136 | 3.791 | 0.3819 | Yes |
| 13 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 142 | 3.728 | 0.4090 | Yes |
| 14 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 176 | 3.554 | 0.4340 | Yes |
| 15 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 182 | 3.517 | 0.4595 | Yes |
| 16 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 205 | 3.343 | 0.4833 | Yes |
| 17 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 207 | 3.333 | 0.5076 | Yes |
| 18 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 238 | 3.159 | 0.5299 | Yes |
| 19 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 253 | 3.078 | 0.5520 | Yes |
| 20 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 274 | 3.005 | 0.5734 | Yes |
| 21 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 542 | 2.202 | 0.5822 | Yes |
| 22 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 582 | 2.113 | 0.5966 | Yes |
| 23 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 584 | 2.105 | 0.6119 | Yes |
| 24 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 701 | 1.904 | 0.6227 | Yes |
| 25 | BLNK | B cell linker [Source:HGNC Symbol;Acc:HGNC:14211] | 1211 | 1.332 | 0.6186 | Yes |
| 26 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 1294 | 1.274 | 0.6257 | Yes |
| 27 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1381 | 1.214 | 0.6322 | Yes |
| 28 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 1493 | 1.148 | 0.6376 | Yes |
| 29 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 1587 | 1.094 | 0.6431 | Yes |
| 30 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1615 | 1.080 | 0.6502 | Yes |
| 31 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1664 | 1.051 | 0.6566 | Yes |
| 32 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1840 | 0.965 | 0.6589 | Yes |
| 33 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 1915 | 0.939 | 0.6638 | Yes |
| 34 | ZNF436 | zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] | 2002 | 0.900 | 0.6680 | Yes |
| 35 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 2172 | 0.827 | 0.6695 | Yes |
| 36 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2370 | 0.759 | 0.6697 | Yes |
| 37 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 2551 | 0.693 | 0.6699 | Yes |
| 38 | UNKL | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] | 2634 | 0.671 | 0.6726 | Yes |
| 39 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 2907 | 0.586 | 0.6695 | No |
| 40 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 3573 | 0.439 | 0.6547 | No |
| 41 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 3617 | 0.428 | 0.6566 | No |
| 42 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 3858 | 0.384 | 0.6530 | No |
| 43 | SPIB | Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242] | 4014 | 0.358 | 0.6514 | No |
| 44 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4225 | 0.313 | 0.6480 | No |
| 45 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 4262 | 0.304 | 0.6492 | No |
| 46 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 4378 | 0.282 | 0.6482 | No |
| 47 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 4925 | 0.194 | 0.6348 | No |
| 48 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 4979 | 0.186 | 0.6347 | No |
| 49 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 5305 | 0.135 | 0.6269 | No |
| 50 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 5504 | 0.109 | 0.6224 | No |
| 51 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 5581 | 0.097 | 0.6210 | No |
| 52 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 5697 | 0.078 | 0.6185 | No |
| 53 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6254 | 0.000 | 0.6034 | No |
| 54 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6686 | 0.000 | 0.5918 | No |
| 55 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 7009 | 0.000 | 0.5831 | No |
| 56 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8870 | 0.000 | 0.5328 | No |
| 57 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9540 | 0.000 | 0.5147 | No |
| 58 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9725 | 0.000 | 0.5097 | No |
| 59 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9792 | 0.000 | 0.5079 | No |
| 60 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9797 | 0.000 | 0.5078 | No |
| 61 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9937 | 0.000 | 0.5040 | No |
| 62 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10420 | 0.000 | 0.4910 | No |
| 63 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10923 | 0.000 | 0.4774 | No |
| 64 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12065 | 0.000 | 0.4465 | No |
| 65 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12382 | 0.000 | 0.4380 | No |
| 66 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12386 | 0.000 | 0.4379 | No |
| 67 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12415 | 0.000 | 0.4371 | No |
| 68 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12451 | 0.000 | 0.4362 | No |
| 69 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13006 | 0.000 | 0.4212 | No |
| 70 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13773 | 0.000 | 0.4005 | No |
| 71 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14530 | 0.000 | 0.3800 | No |
| 72 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15593 | 0.000 | 0.3513 | No |
| 73 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15711 | 0.000 | 0.3481 | No |
| 74 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16136 | 0.000 | 0.3367 | No |
| 75 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16165 | 0.000 | 0.3359 | No |
| 76 | MST1L | macrophage stimulating 1 like [Source:HGNC Symbol;Acc:HGNC:7390] | 16209 | 0.000 | 0.3348 | No |
| 77 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16460 | 0.000 | 0.3280 | No |
| 78 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16470 | 0.000 | 0.3277 | No |
| 79 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17102 | 0.000 | 0.3107 | No |
| 80 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17721 | 0.000 | 0.2940 | No |
| 81 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18306 | 0.000 | 0.2782 | No |
| 82 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18325 | 0.000 | 0.2777 | No |
| 83 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18354 | 0.000 | 0.2769 | No |
| 84 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18755 | 0.000 | 0.2661 | No |
| 85 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18775 | 0.000 | 0.2656 | No |
| 86 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18798 | 0.000 | 0.2650 | No |
| 87 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19331 | 0.000 | 0.2506 | No |
| 88 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20524 | 0.000 | 0.2183 | No |
| 89 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20722 | 0.000 | 0.2130 | No |
| 90 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22249 | 0.000 | 0.1717 | No |
| 91 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22725 | 0.000 | 0.1589 | No |
| 92 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 22788 | 0.000 | 0.1572 | No |
| 93 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 22805 | 0.000 | 0.1568 | No |
| 94 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 22816 | 0.000 | 0.1565 | No |
| 95 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 23128 | 0.000 | 0.1481 | No |
| 96 | UCP1 | uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517] | 23162 | 0.000 | 0.1472 | No |
| 97 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23250 | 0.000 | 0.1448 | No |
| 98 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 24094 | 0.000 | 0.1220 | No |
| 99 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 24790 | 0.000 | 0.1032 | No |
| 100 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25202 | 0.000 | 0.0921 | No |
| 101 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25479 | 0.000 | 0.0847 | No |
| 102 | SLC22A23 | solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106] | 26391 | 0.000 | 0.0600 | No |
| 103 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 28156 | -0.134 | 0.0133 | No |
| 104 | UNC13B | unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] | 28386 | -0.166 | 0.0083 | No |
| 105 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 28981 | -0.243 | -0.0060 | No |
| 106 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 29635 | -0.327 | -0.0213 | No |
| 107 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 29656 | -0.330 | -0.0194 | No |
| 108 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 30096 | -0.394 | -0.0284 | No |
| 109 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 30646 | -0.476 | -0.0398 | No |
| 110 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 30715 | -0.484 | -0.0381 | No |
| 111 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 31001 | -0.532 | -0.0419 | No |
| 112 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 31311 | -0.580 | -0.0461 | No |
| 113 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 31804 | -0.679 | -0.0544 | No |
| 114 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 31843 | -0.688 | -0.0504 | No |
| 115 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 31872 | -0.696 | -0.0461 | No |
| 116 | RUBCNL | rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420] | 32294 | -0.796 | -0.0517 | No |
| 117 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 33420 | -1.115 | -0.0740 | No |
| 118 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33631 | -1.187 | -0.0710 | No |
| 119 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 34283 | -1.427 | -0.0782 | No |
| 120 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35032 | -1.757 | -0.0856 | No |
| 121 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35853 | -2.321 | -0.0909 | No |
| 122 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 36300 | -2.788 | -0.0826 | No |
| 123 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36387 | -2.890 | -0.0638 | No |
| 124 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36695 | -3.366 | -0.0475 | No |
| 125 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36921 | -3.869 | -0.0254 | No |
| 126 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36989 | -4.101 | 0.0027 | No |
