Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_399 |
| Enrichment Score (ES) | 0.6492944 |
| Normalized Enrichment Score (NES) | 1.5253403 |
| Nominal p-value | 0.016304348 |
| FDR q-value | 0.17604887 |
| FWER p-Value | 0.85 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.995 | 0.0651 | Yes |
| 2 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 41 | 4.677 | 0.1250 | Yes |
| 3 | TRAF1 | TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031] | 61 | 4.416 | 0.1820 | Yes |
| 4 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 71 | 4.291 | 0.2377 | Yes |
| 5 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 88 | 4.152 | 0.2914 | Yes |
| 6 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 134 | 3.807 | 0.3398 | Yes |
| 7 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 156 | 3.677 | 0.3872 | Yes |
| 8 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 163 | 3.642 | 0.4345 | Yes |
| 9 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 173 | 3.588 | 0.4810 | Yes |
| 10 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 238 | 3.159 | 0.5205 | Yes |
| 11 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 286 | 2.932 | 0.5574 | Yes |
| 12 | FOSL2 | FOS like 2, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3798] | 379 | 2.608 | 0.5889 | Yes |
| 13 | PEA15 | proliferation and apoptosis adaptor protein 15 [Source:HGNC Symbol;Acc:HGNC:8822] | 416 | 2.501 | 0.6206 | Yes |
| 14 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 643 | 2.000 | 0.6405 | Yes |
| 15 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 1043 | 1.498 | 0.6493 | Yes |
| 16 | LIMS1 | LIM zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:6616] | 3147 | 0.529 | 0.5994 | No |
| 17 | TXNL1 | thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12436] | 3700 | 0.412 | 0.5899 | No |
| 18 | RIPK1 | receptor interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:10019] | 3850 | 0.385 | 0.5909 | No |
| 19 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 4079 | 0.345 | 0.5892 | No |
| 20 | RRAGA | Ras related GTP binding A [Source:HGNC Symbol;Acc:HGNC:16963] | 4320 | 0.293 | 0.5865 | No |
| 21 | MAEA | macrophage erythroblast attacher, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:13731] | 5645 | 0.087 | 0.5519 | No |
| 22 | LTBR | lymphotoxin beta receptor [Source:HGNC Symbol;Acc:HGNC:6718] | 7794 | 0.000 | 0.4939 | No |
| 23 | CASP14 | caspase 14 [Source:HGNC Symbol;Acc:HGNC:1502] | 8979 | 0.000 | 0.4620 | No |
| 24 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 9029 | 0.000 | 0.4607 | No |
| 25 | TNFRSF21 | TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469] | 9051 | 0.000 | 0.4601 | No |
| 26 | CGB3 | chorionic gonadotropin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:1886] | 10133 | 0.000 | 0.4309 | No |
| 27 | PRF1 | perforin 1 [Source:HGNC Symbol;Acc:HGNC:9360] | 11332 | 0.000 | 0.3986 | No |
| 28 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12001 | 0.000 | 0.3805 | No |
| 29 | GZMH | granzyme H [Source:HGNC Symbol;Acc:HGNC:4710] | 12002 | 0.000 | 0.3805 | No |
| 30 | IL24 | interleukin 24 [Source:HGNC Symbol;Acc:HGNC:11346] | 13693 | 0.000 | 0.3349 | No |
| 31 | BIK | BCL2 interacting killer [Source:HGNC Symbol;Acc:HGNC:1051] | 15529 | 0.000 | 0.2853 | No |
| 32 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15711 | 0.000 | 0.2805 | No |
| 33 | C6 | complement C6 [Source:HGNC Symbol;Acc:HGNC:1339] | 16056 | 0.000 | 0.2712 | No |
| 34 | ADRA1A | adrenoceptor alpha 1A [Source:HGNC Symbol;Acc:HGNC:277] | 16461 | 0.000 | 0.2603 | No |
| 35 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16708 | 0.000 | 0.2536 | No |
| 36 | CD38 | CD38 molecule [Source:HGNC Symbol;Acc:HGNC:1667] | 22820 | 0.000 | 0.0886 | No |
| 37 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 29032 | -0.250 | -0.0758 | No |
| 38 | CDK11A | cyclin dependent kinase 11A [Source:HGNC Symbol;Acc:HGNC:1730] | 29714 | -0.341 | -0.0897 | No |
| 39 | BCAP31 | B cell receptor associated protein 31 [Source:HGNC Symbol;Acc:HGNC:16695] | 30186 | -0.406 | -0.0972 | No |
| 40 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 31311 | -0.580 | -0.1199 | No |
| 41 | DAPK1 | death associated protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:2674] | 31791 | -0.676 | -0.1241 | No |
| 42 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 32843 | -0.937 | -0.1402 | No |
| 43 | DUSP6 | dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072] | 33476 | -1.133 | -0.1425 | No |
| 44 | GPR65 | G protein-coupled receptor 65 [Source:HGNC Symbol;Acc:HGNC:4517] | 33543 | -1.155 | -0.1292 | No |
| 45 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 34184 | -1.384 | -0.1285 | No |
| 46 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34289 | -1.430 | -0.1126 | No |
| 47 | PSEN2 | presenilin 2 [Source:HGNC Symbol;Acc:HGNC:9509] | 34633 | -1.568 | -0.1015 | No |
| 48 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 34696 | -1.590 | -0.0824 | No |
| 49 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 35979 | -2.433 | -0.0853 | No |
| 50 | DAP | death associated protein [Source:HGNC Symbol;Acc:HGNC:2672] | 36102 | -2.557 | -0.0553 | No |
| 51 | VDAC1 | voltage dependent anion channel 1 [Source:HGNC Symbol;Acc:HGNC:12669] | 36243 | -2.709 | -0.0238 | No |
| 52 | BNIP3L | BCL2 interacting protein 3 like [Source:HGNC Symbol;Acc:HGNC:1085] | 36821 | -3.574 | 0.0073 | No |
