Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_76 |
| Enrichment Score (ES) | 0.7808558 |
| Normalized Enrichment Score (NES) | 1.9559921 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0053220917 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.995 | 0.0548 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 6 | 4.961 | 0.1092 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 9 | 4.938 | 0.1633 | Yes |
| 4 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 36 | 4.695 | 0.2142 | Yes |
| 5 | TLR3 | toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849] | 62 | 4.409 | 0.2619 | Yes |
| 6 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 71 | 4.291 | 0.3088 | Yes |
| 7 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 124 | 3.892 | 0.3501 | Yes |
| 8 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 201 | 3.397 | 0.3853 | Yes |
| 9 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 238 | 3.159 | 0.4191 | Yes |
| 10 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 254 | 3.077 | 0.4524 | Yes |
| 11 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 283 | 2.959 | 0.4842 | Yes |
| 12 | ADORA2A | adenosine A2a receptor [Source:HGNC Symbol;Acc:HGNC:263] | 392 | 2.559 | 0.5093 | Yes |
| 13 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 407 | 2.528 | 0.5367 | Yes |
| 14 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 410 | 2.520 | 0.5643 | Yes |
| 15 | AOAH | acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548] | 528 | 2.241 | 0.5858 | Yes |
| 16 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 547 | 2.184 | 0.6092 | Yes |
| 17 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 589 | 2.093 | 0.6311 | Yes |
| 18 | TIRAP | TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192] | 600 | 2.079 | 0.6537 | Yes |
| 19 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 612 | 2.056 | 0.6759 | Yes |
| 20 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 639 | 2.009 | 0.6973 | Yes |
| 21 | FPR2 | formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827] | 672 | 1.962 | 0.7180 | Yes |
| 22 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 749 | 1.814 | 0.7358 | Yes |
| 23 | ANXA1 | annexin A1 [Source:HGNC Symbol;Acc:HGNC:533] | 1037 | 1.505 | 0.7446 | Yes |
| 24 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1419 | 1.192 | 0.7474 | Yes |
| 25 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1501 | 1.144 | 0.7578 | Yes |
| 26 | CYBB | cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578] | 1658 | 1.054 | 0.7651 | Yes |
| 27 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1840 | 0.965 | 0.7708 | Yes |
| 28 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 2025 | 0.892 | 0.7757 | Yes |
| 29 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2170 | 0.828 | 0.7809 | Yes |
| 30 | AOC3 | amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550] | 3007 | 0.564 | 0.7645 | No |
| 31 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 3190 | 0.519 | 0.7652 | No |
| 32 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 3669 | 0.417 | 0.7569 | No |
| 33 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4325 | 0.292 | 0.7424 | No |
| 34 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 5084 | 0.170 | 0.7238 | No |
| 35 | ABCF1 | ATP binding cassette subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:70] | 5423 | 0.119 | 0.7160 | No |
| 36 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 5505 | 0.109 | 0.7150 | No |
| 37 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 5953 | 0.041 | 0.7033 | No |
| 38 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6233 | 0.000 | 0.6958 | No |
| 39 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6234 | 0.000 | 0.6958 | No |
| 40 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6253 | 0.000 | 0.6953 | No |
| 41 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6254 | 0.000 | 0.6953 | No |
| 42 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6256 | 0.000 | 0.6953 | No |
| 43 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6263 | 0.000 | 0.6951 | No |
| 44 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6265 | 0.000 | 0.6951 | No |
| 45 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6267 | 0.000 | 0.6951 | No |
| 46 | AOX1 | aldehyde oxidase 1 [Source:HGNC Symbol;Acc:HGNC:553] | 6452 | 0.000 | 0.6901 | No |
| 47 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8356 | 0.000 | 0.6387 | No |
| 48 | LY75 | lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729] | 9002 | 0.000 | 0.6213 | No |
| 49 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 9029 | 0.000 | 0.6205 | No |
| 50 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10591 | 0.000 | 0.5784 | No |
| 51 | S100A12 | S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] | 11533 | 0.000 | 0.5529 | No |
| 52 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 12169 | 0.000 | 0.5358 | No |
| 53 | C4B | complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324] | 15598 | 0.000 | 0.4432 | No |
| 54 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15849 | 0.000 | 0.4364 | No |
| 55 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16055 | 0.000 | 0.4309 | No |
| 56 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16708 | 0.000 | 0.4133 | No |
| 57 | MGLL | monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038] | 17091 | 0.000 | 0.4029 | No |
| 58 | IL9 | interleukin 9 [Source:HGNC Symbol;Acc:HGNC:6029] | 17655 | 0.000 | 0.3877 | No |
| 59 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 17885 | 0.000 | 0.3815 | No |
| 60 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18545 | 0.000 | 0.3637 | No |
| 61 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18781 | 0.000 | 0.3574 | No |
| 62 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18819 | 0.000 | 0.3564 | No |
| 63 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19214 | 0.000 | 0.3457 | No |
| 64 | CXCR2 | C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027] | 19253 | 0.000 | 0.3447 | No |
| 65 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19329 | 0.000 | 0.3427 | No |
| 66 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19331 | 0.000 | 0.3427 | No |
| 67 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19334 | 0.000 | 0.3426 | No |
| 68 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19343 | 0.000 | 0.3424 | No |
| 69 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19347 | 0.000 | 0.3423 | No |
| 70 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 21919 | 0.000 | 0.2728 | No |
| 71 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22723 | 0.000 | 0.2511 | No |
| 72 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22725 | 0.000 | 0.2511 | No |
| 73 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 27699 | -0.082 | 0.1176 | No |
| 74 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 28325 | -0.157 | 0.1025 | No |
| 75 | NFATC4 | nuclear factor of activated T cells 4 [Source:HGNC Symbol;Acc:HGNC:7778] | 30550 | -0.462 | 0.0475 | No |
| 76 | AGER | advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320] | 31184 | -0.561 | 0.0365 | No |
| 77 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 31774 | -0.672 | 0.0280 | No |
| 78 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 32843 | -0.937 | 0.0094 | No |
| 79 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 34696 | -1.590 | -0.0232 | No |
| 80 | ALOX5AP | arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436] | 36659 | -3.299 | -0.0400 | No |
| 81 | ALOX5 | arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435] | 37080 | -4.698 | 0.0003 | No |
