Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_CELL_CYCLE_DNA_REPLICATION |
| Enrichment Score (ES) | -0.7805166 |
| Normalized Enrichment Score (NES) | -1.56596 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.082855955 |
| FWER p-Value | 0.782 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | POLE4 | DNA polymerase epsilon 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:18755] | 626 | 2.032 | 0.0021 | No |
| 2 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1501 | 1.144 | -0.0108 | No |
| 3 | ZMPSTE24 | zinc metallopeptidase STE24 [Source:HGNC Symbol;Acc:HGNC:12877] | 1522 | 1.133 | -0.0007 | No |
| 4 | RTF2 | replication termination factor 2 [Source:HGNC Symbol;Acc:HGNC:15890] | 1985 | 0.906 | -0.0047 | No |
| 5 | INO80 | INO80 complex ATPase subunit [Source:HGNC Symbol;Acc:HGNC:26956] | 1990 | 0.905 | 0.0036 | No |
| 6 | ZNF830 | zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291] | 2296 | 0.780 | 0.0027 | No |
| 7 | SENP2 | SUMO specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:23116] | 3471 | 0.460 | -0.0247 | No |
| 8 | MCMDC2 | minichromosome maintenance domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26368] | 3895 | 0.379 | -0.0326 | No |
| 9 | UPF1 | UPF1 RNA helicase and ATPase [Source:HGNC Symbol;Acc:HGNC:9962] | 5072 | 0.171 | -0.0628 | No |
| 10 | WIZ | WIZ zinc finger [Source:HGNC Symbol;Acc:HGNC:30917] | 6010 | 0.031 | -0.0878 | No |
| 11 | DBF4B | DBF4 zinc finger B [Source:HGNC Symbol;Acc:HGNC:17883] | 13432 | 0.000 | -0.2882 | No |
| 12 | AICDA | activation induced cytidine deaminase [Source:HGNC Symbol;Acc:HGNC:13203] | 18817 | 0.000 | -0.4336 | No |
| 13 | NUGGC | nuclear GTPase, germinal center associated [Source:HGNC Symbol;Acc:HGNC:33550] | 25025 | 0.000 | -0.6013 | No |
| 14 | ZPR1 | ZPR1 zinc finger [Source:HGNC Symbol;Acc:HGNC:13051] | 27305 | -0.031 | -0.6625 | No |
| 15 | POLA2 | DNA polymerase alpha 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:30073] | 27587 | -0.068 | -0.6695 | No |
| 16 | DACH1 | dachshund family transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2663] | 29507 | -0.314 | -0.7184 | No |
| 17 | ORC3 | origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489] | 29943 | -0.372 | -0.7266 | No |
| 18 | DONSON | DNA replication fork stabilization factor DONSON [Source:HGNC Symbol;Acc:HGNC:2993] | 29967 | -0.376 | -0.7237 | No |
| 19 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 30582 | -0.467 | -0.7360 | No |
| 20 | RTEL1 | regulator of telomere elongation helicase 1 [Source:HGNC Symbol;Acc:HGNC:15888] | 31530 | -0.623 | -0.7557 | No |
| 21 | POLE3 | DNA polymerase epsilon 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:13546] | 31996 | -0.729 | -0.7614 | No |
| 22 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 32678 | -0.899 | -0.7714 | Yes |
| 23 | TERF2 | telomeric repeat binding factor 2 [Source:HGNC Symbol;Acc:HGNC:11729] | 32993 | -0.981 | -0.7707 | Yes |
| 24 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.7662 | Yes |
| 25 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.7670 | Yes |
| 26 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 34129 | -1.359 | -0.7678 | Yes |
| 27 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34209 | -1.394 | -0.7569 | Yes |
| 28 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 34332 | -1.446 | -0.7467 | Yes |
| 29 | TERF1 | telomeric repeat binding factor 1 [Source:HGNC Symbol;Acc:HGNC:11728] | 34468 | -1.507 | -0.7362 | Yes |
| 30 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34573 | -1.544 | -0.7246 | Yes |
| 31 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 34756 | -1.623 | -0.7143 | Yes |
| 32 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 34859 | -1.668 | -0.7015 | Yes |
| 33 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 34906 | -1.690 | -0.6869 | Yes |
| 34 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 34952 | -1.712 | -0.6721 | Yes |
| 35 | POLD3 | DNA polymerase delta 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:20932] | 35017 | -1.748 | -0.6575 | Yes |
| 36 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 35063 | -1.780 | -0.6420 | Yes |
| 37 | POLD2 | DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176] | 35203 | -1.861 | -0.6284 | Yes |
| 38 | ATRX | ATRX chromatin remodeler [Source:HGNC Symbol;Acc:HGNC:886] | 35208 | -1.865 | -0.6111 | Yes |
| 39 | POLA1 | DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173] | 35212 | -1.867 | -0.5937 | Yes |
| 40 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.5763 | Yes |
| 41 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35250 | -1.890 | -0.5595 | Yes |
| 42 | RFC1 | replication factor C subunit 1 [Source:HGNC Symbol;Acc:HGNC:9969] | 35307 | -1.922 | -0.5430 | Yes |
| 43 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.5283 | Yes |
| 44 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.5124 | Yes |
| 45 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35634 | -2.139 | -0.4929 | Yes |
| 46 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35976 | -2.431 | -0.4794 | Yes |
| 47 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36023 | -2.475 | -0.4575 | Yes |
| 48 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 36043 | -2.495 | -0.4347 | Yes |
| 49 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 36245 | -2.709 | -0.4147 | Yes |
| 50 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36287 | -2.764 | -0.3900 | Yes |
| 51 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36333 | -2.835 | -0.3647 | Yes |
| 52 | GINS3 | GINS complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25851] | 36370 | -2.875 | -0.3388 | Yes |
| 53 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36408 | -2.907 | -0.3126 | Yes |
| 54 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36416 | -2.915 | -0.2855 | Yes |
| 55 | E2F7 | E2F transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:23820] | 36450 | -2.959 | -0.2587 | Yes |
| 56 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.2311 | Yes |
| 57 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36495 | -3.045 | -0.2035 | Yes |
| 58 | FBXO5 | F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584] | 36501 | -3.050 | -0.1752 | Yes |
| 59 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36573 | -3.161 | -0.1475 | Yes |
| 60 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.1188 | Yes |
| 61 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36677 | -3.335 | -0.0884 | Yes |
| 62 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36704 | -3.383 | -0.0575 | Yes |
| 63 | CHEK2 | checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627] | 36718 | -3.398 | -0.0260 | Yes |
| 64 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36915 | -3.854 | 0.0047 | Yes |
