Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_HOMOLOGOUS_CHROMOSOME_SEGREGATION |
| Enrichment Score (ES) | -0.80249524 |
| Normalized Enrichment Score (NES) | -1.5824622 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.057377756 |
| FWER p-Value | 0.578 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | UBE2B | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | 3897 | 0.378 | -0.0966 | No |
| 2 | MAJIN | membrane anchored junction protein [Source:HGNC Symbol;Acc:HGNC:27441] | 4125 | 0.334 | -0.0952 | No |
| 3 | TEX12 | testis expressed 12 [Source:HGNC Symbol;Acc:HGNC:11734] | 4342 | 0.290 | -0.0944 | No |
| 4 | RNF212 | ring finger protein 212 [Source:HGNC Symbol;Acc:HGNC:27729] | 4983 | 0.185 | -0.1075 | No |
| 5 | ANKRD31 | ankyrin repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:26853] | 7515 | 0.000 | -0.1759 | No |
| 6 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7663 | 0.000 | -0.1798 | No |
| 7 | PTTG2 | pituitary tumor-transforming 2 [Source:HGNC Symbol;Acc:HGNC:9691] | 7731 | 0.000 | -0.1816 | No |
| 8 | RAD21L1 | RAD21 cohesin complex component like 1 [Source:HGNC Symbol;Acc:HGNC:16271] | 7882 | 0.000 | -0.1857 | No |
| 9 | C1orf146 | chromosome 1 open reading frame 146 [Source:HGNC Symbol;Acc:HGNC:24032] | 9986 | 0.000 | -0.2425 | No |
| 10 | MEIOC | meiosis specific with coiled-coil domain [Source:HGNC Symbol;Acc:HGNC:26670] | 10626 | 0.000 | -0.2597 | No |
| 11 | RNF212B | ring finger protein 212B [Source:HGNC Symbol;Acc:HGNC:20438] | 11458 | 0.000 | -0.2822 | No |
| 12 | IHO1 | interactor of HORMAD1 1 [Source:HGNC Symbol;Acc:HGNC:27945] | 12719 | 0.000 | -0.3162 | No |
| 13 | MEIKIN | meiotic kinetochore factor [Source:HGNC Symbol;Acc:HGNC:51253] | 12779 | 0.000 | -0.3178 | No |
| 14 | TERB1 | telomere repeat binding bouquet formation protein 1 [Source:HGNC Symbol;Acc:HGNC:26675] | 13062 | 0.000 | -0.3254 | No |
| 15 | TERB2 | telomere repeat binding bouquet formation protein 2 [Source:HGNC Symbol;Acc:HGNC:28520] | 13063 | 0.000 | -0.3254 | No |
| 16 | REC8 | REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879] | 13616 | 0.000 | -0.3403 | No |
| 17 | TEX11 | testis expressed 11 [Source:HGNC Symbol;Acc:HGNC:11733] | 15129 | 0.000 | -0.3811 | No |
| 18 | TEX15 | testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738] | 15130 | 0.000 | -0.3811 | No |
| 19 | MEI4 | meiotic double-stranded break formation protein 4 [Source:HGNC Symbol;Acc:HGNC:43638] | 16347 | 0.000 | -0.4140 | No |
| 20 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16847 | 0.000 | -0.4275 | No |
| 21 | SYCE3 | synaptonemal complex central element protein 3 [Source:HGNC Symbol;Acc:HGNC:35245] | 16934 | 0.000 | -0.4298 | No |
| 22 | SYCE1 | synaptonemal complex central element protein 1 [Source:HGNC Symbol;Acc:HGNC:28852] | 16935 | 0.000 | -0.4298 | No |
| 23 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17781 | 0.000 | -0.4526 | No |
| 24 | CCNB1IP1 | cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437] | 18225 | 0.000 | -0.4646 | No |
| 25 | PTTG3P | pituitary tumor-transforming 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:13422] | 18403 | 0.000 | -0.4693 | No |
| 26 | P3H4 | prolyl 3-hydroxylase family member 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:16946] | 18476 | 0.000 | -0.4713 | No |
| 27 | SPO11 | SPO11 initiator of meiotic double stranded breaks [Source:HGNC Symbol;Acc:HGNC:11250] | 19337 | 0.000 | -0.4945 | No |
| 28 | C14orf39 | chromosome 14 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:19849] | 19578 | 0.000 | -0.5010 | No |
| 29 | SYCE1L | synaptonemal complex central element protein 1 like [Source:HGNC Symbol;Acc:HGNC:37236] | 22502 | 0.000 | -0.5799 | No |
| 30 | SPATA22 | spermatogenesis associated 22 [Source:HGNC Symbol;Acc:HGNC:30705] | 24758 | 0.000 | -0.6408 | No |
| 31 | FMN2 | formin 2 [Source:HGNC Symbol;Acc:HGNC:14074] | 26757 | 0.000 | -0.6948 | No |
| 32 | MAEL | maelstrom spermatogenic transposon silencer [Source:HGNC Symbol;Acc:HGNC:25929] | 26825 | 0.000 | -0.6966 | No |
| 33 | BAG6 | BAG cochaperone 6 [Source:HGNC Symbol;Acc:HGNC:13919] | 27989 | -0.117 | -0.7253 | No |
| 34 | MSH4 | mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:7327] | 28142 | -0.133 | -0.7264 | No |
| 35 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 28421 | -0.170 | -0.7301 | No |
| 36 | HORMAD1 | HORMA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25245] | 30864 | -0.509 | -0.7845 | No |
| 37 | SYCP2 | synaptonemal complex protein 2 [Source:HGNC Symbol;Acc:HGNC:11490] | 31533 | -0.624 | -0.7883 | Yes |
| 38 | CENPC | centromere protein C [Source:HGNC Symbol;Acc:HGNC:1854] | 31955 | -0.717 | -0.7834 | Yes |
| 39 | MEIOB | meiosis specific with OB-fold [Source:HGNC Symbol;Acc:HGNC:28569] | 32071 | -0.748 | -0.7695 | Yes |
| 40 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32217 | -0.779 | -0.7557 | Yes |
| 41 | ATM | ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795] | 32594 | -0.872 | -0.7461 | Yes |
| 42 | SIRT7 | sirtuin 7 [Source:HGNC Symbol;Acc:HGNC:14935] | 33341 | -1.090 | -0.7415 | Yes |
| 43 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 33347 | -1.092 | -0.7168 | Yes |
| 44 | BRIP1 | BRCA1 interacting protein C-terminal helicase 1 [Source:HGNC Symbol;Acc:HGNC:20473] | 33407 | -1.112 | -0.6932 | Yes |
| 45 | AGO4 | argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424] | 33463 | -1.128 | -0.6690 | Yes |
| 46 | NDC1 | NDC1 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:25525] | 33581 | -1.169 | -0.6456 | Yes |
| 47 | PRDM9 | PR/SET domain 9 [Source:HGNC Symbol;Acc:HGNC:13994] | 33616 | -1.180 | -0.6197 | Yes |
| 48 | KASH5 | KASH domain containing 5 [Source:HGNC Symbol;Acc:HGNC:26520] | 34556 | -1.536 | -0.6102 | Yes |
| 49 | ZCWPW1 | zinc finger CW-type and PWWP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23486] | 34588 | -1.550 | -0.5759 | Yes |
| 50 | FANCD2 | FA complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585] | 34933 | -1.702 | -0.5465 | Yes |
| 51 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35107 | -1.803 | -0.5102 | Yes |
| 52 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 35128 | -1.813 | -0.4696 | Yes |
| 53 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35625 | -2.133 | -0.4346 | Yes |
| 54 | MLH3 | mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128] | 35679 | -2.172 | -0.3866 | Yes |
| 55 | RAD21 | RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811] | 35700 | -2.191 | -0.3374 | Yes |
| 56 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36189 | -2.647 | -0.2905 | Yes |
| 57 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36517 | -3.064 | -0.2297 | Yes |
| 58 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36602 | -3.206 | -0.1592 | Yes |
| 59 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36620 | -3.234 | -0.0862 | Yes |
| 60 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37042 | -4.354 | 0.0013 | Yes |
