Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_SEROTONIN_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.8736653 |
| Normalized Enrichment Score (NES) | -1.6345131 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.015556503 |
| FWER p-Value | 0.111 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HTR7 | 5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302] | 5597 | 0.093 | -0.1357 | No |
| 2 | OR6T1 | olfactory receptor family 6 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:14848] | 14287 | 0.000 | -0.3702 | No |
| 3 | OR5T3 | olfactory receptor family 5 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:15297] | 14736 | 0.000 | -0.3823 | No |
| 4 | OR5T2 | olfactory receptor family 5 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:15296] | 14738 | 0.000 | -0.3824 | No |
| 5 | HTR4 | 5-hydroxytryptamine receptor 4 [Source:HGNC Symbol;Acc:HGNC:5299] | 15499 | 0.000 | -0.4029 | No |
| 6 | HTR6 | 5-hydroxytryptamine receptor 6 [Source:HGNC Symbol;Acc:HGNC:5301] | 15501 | 0.000 | -0.4029 | No |
| 7 | HTR1E | 5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291] | 15559 | 0.000 | -0.4044 | No |
| 8 | HTR1F | 5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292] | 15561 | 0.000 | -0.4045 | No |
| 9 | HTR1D | 5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289] | 15562 | 0.000 | -0.4045 | No |
| 10 | HTR1A | 5-hydroxytryptamine receptor 1A [Source:HGNC Symbol;Acc:HGNC:5286] | 15563 | 0.000 | -0.4045 | No |
| 11 | HTR2B | 5-hydroxytryptamine receptor 2B [Source:HGNC Symbol;Acc:HGNC:5294] | 15570 | 0.000 | -0.4046 | No |
| 12 | HTR2C | 5-hydroxytryptamine receptor 2C [Source:HGNC Symbol;Acc:HGNC:5295] | 15571 | 0.000 | -0.4046 | No |
| 13 | HTR2A | 5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293] | 15572 | 0.000 | -0.4046 | No |
| 14 | HTR3E | 5-hydroxytryptamine receptor 3E [Source:HGNC Symbol;Acc:HGNC:24005] | 15576 | 0.000 | -0.4047 | No |
| 15 | HTR3C | 5-hydroxytryptamine receptor 3C [Source:HGNC Symbol;Acc:HGNC:24003] | 15577 | 0.000 | -0.4047 | No |
| 16 | HTR3D | 5-hydroxytryptamine receptor 3D [Source:HGNC Symbol;Acc:HGNC:24004] | 15578 | 0.000 | -0.4047 | No |
| 17 | HTR3A | 5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297] | 15579 | 0.000 | -0.4047 | No |
| 18 | HTR3B | 5-hydroxytryptamine receptor 3B [Source:HGNC Symbol;Acc:HGNC:5298] | 15580 | 0.000 | -0.4047 | No |
| 19 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15589 | 0.000 | -0.4049 | No |
| 20 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17754 | 0.000 | -0.4633 | No |
| 21 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17756 | 0.000 | -0.4633 | No |
| 22 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17757 | 0.000 | -0.4633 | No |
| 23 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17758 | 0.000 | -0.4633 | No |
| 24 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18392 | 0.000 | -0.4804 | No |
| 25 | OR10J5 | olfactory receptor family 10 subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:14993] | 25422 | 0.000 | -0.6701 | No |
| 26 | OR10H1 | olfactory receptor family 10 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8172] | 25444 | 0.000 | -0.6707 | No |
| 27 | OR10H3 | olfactory receptor family 10 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:8174] | 25445 | 0.000 | -0.6707 | No |
| 28 | OR10H2 | olfactory receptor family 10 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:8173] | 25446 | 0.000 | -0.6707 | No |
| 29 | OR10H4 | olfactory receptor family 10 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15388] | 25447 | 0.000 | -0.6707 | No |
| 30 | OR11H4 | olfactory receptor family 11 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15347] | 25664 | 0.000 | -0.6765 | No |
| 31 | OR11H7 | olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15350] | 25673 | 0.000 | -0.6767 | No |
| 32 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 26429 | 0.000 | -0.6971 | No |
| 33 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 26432 | 0.000 | -0.6972 | No |
| 34 | HRH2 | histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183] | 26434 | 0.000 | -0.6972 | No |
| 35 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 26437 | 0.000 | -0.6973 | No |
| 36 | OR10J6P | olfactory receptor family 10 subfamily J member 6 pseudogene [Source:HGNC Symbol;Acc:HGNC:14994] | 26731 | 0.000 | -0.7052 | No |
| 37 | OR10H5 | olfactory receptor family 10 subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:15389] | 28358 | -0.164 | -0.7220 | Yes |
| 38 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 33977 | -1.304 | -0.6587 | Yes |
| 39 | HTR1B | 5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287] | 37063 | -4.507 | 0.0007 | Yes |
