Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | -0.8288218 |
| Normalized Enrichment Score (NES) | -1.6325884 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.014510594 |
| FWER p-Value | 0.118 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GRID1 | glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575] | 5638 | 0.088 | -0.1403 | No |
| 2 | GRIA1 | glutamate ionotropic receptor AMPA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4571] | 9014 | 0.000 | -0.2314 | No |
| 3 | GRIA3 | glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573] | 9025 | 0.000 | -0.2317 | No |
| 4 | GRID2 | glutamate ionotropic receptor delta type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4576] | 9042 | 0.000 | -0.2321 | No |
| 5 | GRIK3 | glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581] | 9131 | 0.000 | -0.2345 | No |
| 6 | GRIK4 | glutamate ionotropic receptor kainate type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4582] | 9132 | 0.000 | -0.2345 | No |
| 7 | GRIK1 | glutamate ionotropic receptor kainate type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4579] | 9133 | 0.000 | -0.2345 | No |
| 8 | GRM1 | glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593] | 9822 | 0.000 | -0.2531 | No |
| 9 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 9826 | 0.000 | -0.2532 | No |
| 10 | GRIN2C | glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587] | 10197 | 0.000 | -0.2631 | No |
| 11 | GRIN3A | glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767] | 10201 | 0.000 | -0.2632 | No |
| 12 | GLRA1 | glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326] | 12868 | 0.000 | -0.3352 | No |
| 13 | GLRA2 | glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327] | 12872 | 0.000 | -0.3353 | No |
| 14 | CHRFAM7A | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion [Source:HGNC Symbol;Acc:HGNC:15781] | 13128 | 0.000 | -0.3422 | No |
| 15 | GABRE | gamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085] | 17242 | 0.000 | -0.4533 | No |
| 16 | CHRND | cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965] | 17743 | 0.000 | -0.4668 | No |
| 17 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17744 | 0.000 | -0.4668 | No |
| 18 | CHRNE | cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966] | 17745 | 0.000 | -0.4668 | No |
| 19 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17754 | 0.000 | -0.4670 | No |
| 20 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17756 | 0.000 | -0.4670 | No |
| 21 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17757 | 0.000 | -0.4670 | No |
| 22 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17758 | 0.000 | -0.4670 | No |
| 23 | ADRB1 | adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285] | 17859 | 0.000 | -0.4697 | No |
| 24 | DRD1 | dopamine receptor D1 [Source:HGNC Symbol;Acc:HGNC:3020] | 18388 | 0.000 | -0.4840 | No |
| 25 | DRD2 | dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023] | 18389 | 0.000 | -0.4840 | No |
| 26 | DRD3 | dopamine receptor D3 [Source:HGNC Symbol;Acc:HGNC:3024] | 18391 | 0.000 | -0.4840 | No |
| 27 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18392 | 0.000 | -0.4840 | No |
| 28 | DRD5 | dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026] | 18393 | 0.000 | -0.4840 | No |
| 29 | CHRNA10 | cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800] | 19665 | 0.000 | -0.5183 | No |
| 30 | GABRG3 | gamma-aminobutyric acid type A receptor subunit gamma3 [Source:HGNC Symbol;Acc:HGNC:4088] | 19765 | 0.000 | -0.5210 | No |
| 31 | GABRG2 | gamma-aminobutyric acid type A receptor subunit gamma2 [Source:HGNC Symbol;Acc:HGNC:4087] | 19766 | 0.000 | -0.5210 | No |
| 32 | GABRG1 | gamma-aminobutyric acid type A receptor subunit gamma1 [Source:HGNC Symbol;Acc:HGNC:4086] | 19767 | 0.000 | -0.5210 | No |
| 33 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19814 | 0.000 | -0.5222 | No |
| 34 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 19815 | 0.000 | -0.5222 | No |
| 35 | GABRA2 | gamma-aminobutyric acid type A receptor subunit alpha2 [Source:HGNC Symbol;Acc:HGNC:4076] | 19857 | 0.000 | -0.5233 | No |
| 36 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 19858 | 0.000 | -0.5233 | No |
| 37 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 19859 | 0.000 | -0.5233 | No |
| 38 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 19860 | 0.000 | -0.5233 | No |
| 39 | GABRA4 | gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078] | 19861 | 0.000 | -0.5233 | No |
| 40 | GABRA3 | gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077] | 19862 | 0.000 | -0.5233 | No |
| 41 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 19996 | 0.000 | -0.5269 | No |
| 42 | GABRR1 | gamma-aminobutyric acid type A receptor subunit rho1 [Source:HGNC Symbol;Acc:HGNC:4090] | 19998 | 0.000 | -0.5270 | No |
| 43 | GLRB | glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329] | 21691 | 0.000 | -0.5727 | No |
| 44 | GABBR1 | gamma-aminobutyric acid type B receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:4070] | 22090 | 0.000 | -0.5834 | No |
| 45 | CHRNB3 | cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963] | 24473 | 0.000 | -0.6477 | No |
| 46 | CHRNA1 | cholinergic receptor nicotinic alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:1955] | 24496 | 0.000 | -0.6483 | No |
| 47 | CHRNA3 | cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957] | 24499 | 0.000 | -0.6484 | No |
| 48 | CHRNA2 | cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956] | 24500 | 0.000 | -0.6484 | No |
| 49 | CHRNA5 | cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959] | 24501 | 0.000 | -0.6484 | No |
| 50 | CHRNA4 | cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958] | 24502 | 0.000 | -0.6484 | No |
| 51 | CHRNA7 | cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960] | 24503 | 0.000 | -0.6484 | No |
| 52 | CHRNA6 | cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963] | 24506 | 0.000 | -0.6484 | No |
| 53 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 24509 | 0.000 | -0.6485 | No |
| 54 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 26432 | 0.000 | -0.7004 | No |
| 55 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 26437 | 0.000 | -0.7005 | No |
| 56 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 27499 | -0.058 | -0.7211 | No |
| 57 | CHRNB4 | cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964] | 31487 | -0.614 | -0.7448 | Yes |
| 58 | CHRNB1 | cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961] | 32370 | -0.815 | -0.6569 | Yes |
| 59 | ANXA9 | annexin A9 [Source:HGNC Symbol;Acc:HGNC:547] | 33138 | -1.023 | -0.5375 | Yes |
| 60 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 33977 | -1.304 | -0.3815 | Yes |
| 61 | GRIK5 | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | 34532 | -1.528 | -0.1872 | Yes |
| 62 | CHRNB2 | cholinergic receptor nicotinic beta 2 subunit [Source:HGNC Symbol;Acc:HGNC:1962] | 35221 | -1.871 | 0.0505 | Yes |
