Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CAHOY_OLIGODENDROCUTIC |
| Enrichment Score (ES) | -0.67005277 |
| Normalized Enrichment Score (NES) | -1.3787915 |
| Nominal p-value | 0.0033594626 |
| FDR q-value | 0.07627137 |
| FWER p-Value | 0.626 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DOCK10 | dedicator of cytokinesis 10 [Source:HGNC Symbol;Acc:HGNC:23479] | 331 | 2.798 | 0.0217 | No |
| 2 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 643 | 2.000 | 0.0353 | No |
| 3 | EFHD2 | EF-hand domain family member D2 [Source:HGNC Symbol;Acc:HGNC:28670] | 705 | 1.892 | 0.0544 | No |
| 4 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 777 | 1.779 | 0.0720 | No |
| 5 | HIP1R | huntingtin interacting protein 1 related [Source:HGNC Symbol;Acc:HGNC:18415] | 1900 | 0.945 | 0.0520 | No |
| 6 | USP16 | ubiquitin specific peptidase 16 [Source:HGNC Symbol;Acc:HGNC:12614] | 1923 | 0.933 | 0.0617 | No |
| 7 | ADGRL2 | adhesion G protein-coupled receptor L2 [Source:HGNC Symbol;Acc:HGNC:18582] | 2838 | 0.609 | 0.0436 | No |
| 8 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 3515 | 0.450 | 0.0303 | No |
| 9 | NGRN | neugrin, neurite outgrowth associated [Source:HGNC Symbol;Acc:HGNC:18077] | 3530 | 0.448 | 0.0348 | No |
| 10 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 3931 | 0.374 | 0.0281 | No |
| 11 | RBM11 | RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897] | 4201 | 0.318 | 0.0243 | No |
| 12 | PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9581] | 4483 | 0.265 | 0.0196 | No |
| 13 | SOX10 | SRY-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11190] | 5259 | 0.142 | 0.0002 | No |
| 14 | BCR | BCR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:1014] | 5419 | 0.119 | -0.0028 | No |
| 15 | WIPF1 | WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736] | 5761 | 0.069 | -0.0112 | No |
| 16 | CCN2 | cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500] | 5770 | 0.068 | -0.0107 | No |
| 17 | FBXO7 | F-box protein 7 [Source:HGNC Symbol;Acc:HGNC:13586] | 5951 | 0.041 | -0.0151 | No |
| 18 | NCMAP | non-compact myelin associated protein [Source:HGNC Symbol;Acc:HGNC:29332] | 6742 | 0.000 | -0.0365 | No |
| 19 | PRKCQ | protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410] | 6791 | 0.000 | -0.0378 | No |
| 20 | GAL3ST1 | galactose-3-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24240] | 6880 | 0.000 | -0.0401 | No |
| 21 | CNTNAP2 | contactin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:13830] | 7222 | 0.000 | -0.0494 | No |
| 22 | FA2H | fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197] | 7462 | 0.000 | -0.0558 | No |
| 23 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 8062 | 0.000 | -0.0720 | No |
| 24 | MAP6D1 | MAP6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25753] | 8243 | 0.000 | -0.0769 | No |
| 25 | NINJ2 | ninjurin 2 [Source:HGNC Symbol;Acc:HGNC:7825] | 9721 | 0.000 | -0.1168 | No |
| 26 | PLLP | plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553] | 9915 | 0.000 | -0.1220 | No |
| 27 | TSPAN2 | tetraspanin 2 [Source:HGNC Symbol;Acc:HGNC:20659] | 11354 | 0.000 | -0.1609 | No |
| 28 | BACE1 | beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933] | 11553 | 0.000 | -0.1662 | No |
| 29 | ATP10B | ATPase phospholipid transporting 10B (putative) [Source:HGNC Symbol;Acc:HGNC:13543] | 11991 | 0.000 | -0.1781 | No |
| 30 | TENM1 | teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117] | 12687 | 0.000 | -0.1968 | No |
| 31 | DMRTA1 | DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826] | 14827 | 0.000 | -0.2547 | No |
| 32 | GJE1 | gap junction protein epsilon 1 [Source:HGNC Symbol;Acc:HGNC:33251] | 15410 | 0.000 | -0.2704 | No |
| 33 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15982 | 0.000 | -0.2858 | No |
| 34 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16311 | 0.000 | -0.2947 | No |
| 35 | GPR17 | G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471] | 17408 | 0.000 | -0.3243 | No |
| 36 | SEMA3D | semaphorin 3D [Source:HGNC Symbol;Acc:HGNC:10726] | 17787 | 0.000 | -0.3346 | No |
| 37 | BFSP2 | beaded filament structural protein 2 [Source:HGNC Symbol;Acc:HGNC:1041] | 18120 | 0.000 | -0.3435 | No |
| 38 | FEZF2 | FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506] | 18552 | 0.000 | -0.3552 | No |
| 39 | AGAP11 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 [Source:HGNC Symbol;Acc:HGNC:29421] | 19546 | 0.000 | -0.3820 | No |
| 40 | DUSP15 | dual specificity phosphatase 15 [Source:HGNC Symbol;Acc:HGNC:16236] | 20492 | 0.000 | -0.4076 | No |
| 41 | GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488] | 20603 | 0.000 | -0.4105 | No |
| 42 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21158 | 0.000 | -0.4255 | No |
| 43 | ZNF536 | zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] | 21639 | 0.000 | -0.4385 | No |
| 44 | FAM89A | family with sequence similarity 89 member A [Source:HGNC Symbol;Acc:HGNC:25057] | 22436 | 0.000 | -0.4600 | No |
| 45 | LHFPL6 | LHFPL tetraspan subfamily member 6 [Source:HGNC Symbol;Acc:HGNC:6586] | 22496 | 0.000 | -0.4616 | No |
| 46 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 24143 | 0.000 | -0.5061 | No |
| 47 | UGT8 | UDP glycosyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:12555] | 24601 | 0.000 | -0.5185 | No |
| 48 | CSDC2 | cold shock domain containing C2 [Source:HGNC Symbol;Acc:HGNC:30359] | 25566 | 0.000 | -0.5445 | No |
| 49 | FIGN | fidgetin, microtubule severing factor [Source:HGNC Symbol;Acc:HGNC:13285] | 25726 | 0.000 | -0.5488 | No |
| 50 | SOX8 | SRY-box transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:11203] | 25796 | 0.000 | -0.5507 | No |
| 51 | ZNF276 | zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330] | 27211 | -0.011 | -0.5888 | No |
| 52 | POP4 | POP4 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30081] | 27355 | -0.038 | -0.5922 | No |
| 53 | CDR2L | cerebellar degeneration related protein 2 like [Source:HGNC Symbol;Acc:HGNC:29999] | 27574 | -0.066 | -0.5974 | No |
| 54 | COL20A1 | collagen type XX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:14670] | 28024 | -0.122 | -0.6082 | No |
| 55 | SRPK3 | SRSF protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:11402] | 28959 | -0.239 | -0.6308 | No |
| 56 | KCTD1 | potassium channel tetramerization domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18249] | 29027 | -0.250 | -0.6299 | No |
| 57 | EPN2 | epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639] | 29283 | -0.285 | -0.6337 | No |
| 58 | CPOX | coproporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:2321] | 29487 | -0.312 | -0.6357 | No |
| 59 | TLCD3A | TLC domain containing 3A [Source:HGNC Symbol;Acc:HGNC:29646] | 29928 | -0.370 | -0.6436 | No |
| 60 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 30012 | -0.381 | -0.6416 | No |
| 61 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 30065 | -0.389 | -0.6388 | No |
| 62 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 30672 | -0.479 | -0.6499 | No |
| 63 | GNG8 | G protein subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:19664] | 31128 | -0.552 | -0.6562 | No |
| 64 | ERBB3 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 31315 | -0.580 | -0.6548 | No |
| 65 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 31614 | -0.639 | -0.6559 | No |
| 66 | SIRT2 | sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886] | 31824 | -0.684 | -0.6540 | No |
| 67 | BCAS1 | brain enriched myelin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:974] | 32287 | -0.794 | -0.6578 | No |
| 68 | RNF122 | ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147] | 32742 | -0.914 | -0.6600 | Yes |
| 69 | RNASEH2B | ribonuclease H2 subunit B [Source:HGNC Symbol;Acc:HGNC:25671] | 32811 | -0.927 | -0.6517 | Yes |
| 70 | DUSP19 | dual specificity phosphatase 19 [Source:HGNC Symbol;Acc:HGNC:18894] | 32872 | -0.945 | -0.6430 | Yes |
| 71 | NR2C1 | nuclear receptor subfamily 2 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7971] | 32953 | -0.970 | -0.6345 | Yes |
| 72 | PUS7 | pseudouridine synthase 7 [Source:HGNC Symbol;Acc:HGNC:26033] | 33322 | -1.085 | -0.6325 | Yes |
| 73 | SPEG | striated muscle enriched protein kinase [Source:HGNC Symbol;Acc:HGNC:16901] | 33349 | -1.093 | -0.6212 | Yes |
| 74 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 33744 | -1.226 | -0.6184 | Yes |
| 75 | PKIG | cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019] | 33803 | -1.246 | -0.6063 | Yes |
| 76 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 34333 | -1.446 | -0.6048 | Yes |
| 77 | DOCK7 | dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:HGNC:19190] | 34518 | -1.521 | -0.5931 | Yes |
| 78 | AP5Z1 | adaptor related protein complex 5 subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:22197] | 34759 | -1.624 | -0.5817 | Yes |
| 79 | SERINC5 | serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825] | 34802 | -1.644 | -0.5648 | Yes |
| 80 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 34813 | -1.648 | -0.5470 | Yes |
| 81 | PPP1R21 | protein phosphatase 1 regulatory subunit 21 [Source:HGNC Symbol;Acc:HGNC:30595] | 34856 | -1.667 | -0.5299 | Yes |
| 82 | DCPS | decapping enzyme, scavenger [Source:HGNC Symbol;Acc:HGNC:29812] | 35069 | -1.784 | -0.5160 | Yes |
| 83 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 35578 | -2.103 | -0.5067 | Yes |
| 84 | RTKN | rhotekin [Source:HGNC Symbol;Acc:HGNC:10466] | 35637 | -2.140 | -0.4848 | Yes |
| 85 | KIAA1958 | KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427] | 35639 | -2.141 | -0.4613 | Yes |
| 86 | P4HA2 | prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547] | 35735 | -2.215 | -0.4396 | Yes |
| 87 | PLXNB3 | plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105] | 35893 | -2.364 | -0.4179 | Yes |
| 88 | RCBTB1 | RCC1 and BTB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:18243] | 35929 | -2.395 | -0.3926 | Yes |
| 89 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 35990 | -2.443 | -0.3674 | Yes |
| 90 | CILK1 | ciliogenesis associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:21219] | 36134 | -2.580 | -0.3430 | Yes |
| 91 | IFFO1 | intermediate filament family orphan 1 [Source:HGNC Symbol;Acc:HGNC:24970] | 36139 | -2.586 | -0.3147 | Yes |
| 92 | CLYBL | citramalyl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:18355] | 36386 | -2.889 | -0.2896 | Yes |
| 93 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36396 | -2.896 | -0.2581 | Yes |
| 94 | MAP3K15 | mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689] | 36583 | -3.176 | -0.2283 | Yes |
| 95 | ELOVL6 | ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] | 36615 | -3.229 | -0.1937 | Yes |
| 96 | ABHD8 | abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759] | 36750 | -3.440 | -0.1596 | Yes |
| 97 | PRKAG2 | protein kinase AMP-activated non-catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:9386] | 36765 | -3.476 | -0.1218 | Yes |
| 98 | LCORL | ligand dependent nuclear receptor corepressor like [Source:HGNC Symbol;Acc:HGNC:30776] | 36834 | -3.613 | -0.0840 | Yes |
| 99 | LRRC75A | leucine rich repeat containing 75A [Source:HGNC Symbol;Acc:HGNC:32403] | 36975 | -4.044 | -0.0435 | Yes |
| 100 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 37026 | -4.242 | 0.0017 | Yes |
