Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.6021988 |
| Normalized Enrichment Score (NES) | -1.2627753 |
| Nominal p-value | 0.055254605 |
| FDR q-value | 0.3204586 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 15 | 4.880 | 0.0404 | No |
| 2 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 99 | 4.056 | 0.0720 | No |
| 3 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 651 | 1.993 | 0.0737 | No |
| 4 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 678 | 1.953 | 0.0893 | No |
| 5 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 835 | 1.713 | 0.0994 | No |
| 6 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 947 | 1.610 | 0.1098 | No |
| 7 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 1254 | 1.303 | 0.1124 | No |
| 8 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 1474 | 1.158 | 0.1162 | No |
| 9 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 1646 | 1.061 | 0.1204 | No |
| 10 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 1772 | 0.991 | 0.1253 | No |
| 11 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 1904 | 0.943 | 0.1297 | No |
| 12 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 3654 | 0.421 | 0.0859 | No |
| 13 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 3822 | 0.390 | 0.0846 | No |
| 14 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 3912 | 0.376 | 0.0853 | No |
| 15 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 4054 | 0.350 | 0.0844 | No |
| 16 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 4078 | 0.345 | 0.0867 | No |
| 17 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 4593 | 0.247 | 0.0749 | No |
| 18 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 4751 | 0.224 | 0.0725 | No |
| 19 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 5477 | 0.112 | 0.0538 | No |
| 20 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 5515 | 0.107 | 0.0537 | No |
| 21 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 5541 | 0.103 | 0.0539 | No |
| 22 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 6110 | 0.015 | 0.0386 | No |
| 23 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 6132 | 0.011 | 0.0382 | No |
| 24 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 6788 | 0.000 | 0.0204 | No |
| 25 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7611 | 0.000 | -0.0018 | No |
| 26 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 7744 | 0.000 | -0.0054 | No |
| 27 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 8906 | 0.000 | -0.0368 | No |
| 28 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10178 | 0.000 | -0.0712 | No |
| 29 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11073 | 0.000 | -0.0953 | No |
| 30 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 11321 | 0.000 | -0.1020 | No |
| 31 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12823 | 0.000 | -0.1426 | No |
| 32 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13120 | 0.000 | -0.1506 | No |
| 33 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13284 | 0.000 | -0.1550 | No |
| 34 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 13342 | 0.000 | -0.1566 | No |
| 35 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 13427 | 0.000 | -0.1589 | No |
| 36 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 13868 | 0.000 | -0.1708 | No |
| 37 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14208 | 0.000 | -0.1799 | No |
| 38 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15833 | 0.000 | -0.2239 | No |
| 39 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 15838 | 0.000 | -0.2240 | No |
| 40 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16216 | 0.000 | -0.2342 | No |
| 41 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17827 | 0.000 | -0.2777 | No |
| 42 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17845 | 0.000 | -0.2782 | No |
| 43 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18354 | 0.000 | -0.2919 | No |
| 44 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 21595 | 0.000 | -0.3796 | No |
| 45 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 22297 | 0.000 | -0.3985 | No |
| 46 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 22341 | 0.000 | -0.3997 | No |
| 47 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 22535 | 0.000 | -0.4049 | No |
| 48 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 23383 | 0.000 | -0.4278 | No |
| 49 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 25342 | 0.000 | -0.4808 | No |
| 50 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 25500 | 0.000 | -0.4851 | No |
| 51 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 25689 | 0.000 | -0.4901 | No |
| 52 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 26912 | 0.000 | -0.5232 | No |
| 53 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 27259 | -0.022 | -0.5324 | No |
| 54 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 27365 | -0.040 | -0.5349 | No |
| 55 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 27386 | -0.043 | -0.5351 | No |
| 56 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 27525 | -0.061 | -0.5383 | No |
| 57 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 27605 | -0.070 | -0.5398 | No |
| 58 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 27705 | -0.083 | -0.5418 | No |
| 59 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 27998 | -0.118 | -0.5487 | No |
| 60 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 28632 | -0.197 | -0.5642 | No |
| 61 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 28798 | -0.222 | -0.5668 | No |
| 62 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 28828 | -0.225 | -0.5657 | No |
| 63 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 29202 | -0.273 | -0.5736 | No |
| 64 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 29260 | -0.283 | -0.5727 | No |
| 65 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 29713 | -0.340 | -0.5821 | No |
| 66 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 30445 | -0.443 | -0.5982 | Yes |
| 67 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 30510 | -0.455 | -0.5961 | Yes |
| 68 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 30635 | -0.474 | -0.5955 | Yes |
| 69 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 30655 | -0.477 | -0.5921 | Yes |
| 70 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 31031 | -0.536 | -0.5977 | Yes |
| 71 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 31071 | -0.543 | -0.5942 | Yes |
| 72 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 31094 | -0.546 | -0.5903 | Yes |
| 73 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 31251 | -0.573 | -0.5897 | Yes |
| 74 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 31397 | -0.597 | -0.5886 | Yes |
| 75 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 31561 | -0.629 | -0.5878 | Yes |
| 76 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 31623 | -0.641 | -0.5841 | Yes |
| 77 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 31929 | -0.711 | -0.5864 | Yes |
| 78 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 32103 | -0.755 | -0.5848 | Yes |
| 79 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 32111 | -0.758 | -0.5786 | Yes |
| 80 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 32259 | -0.788 | -0.5760 | Yes |
| 81 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 32372 | -0.816 | -0.5722 | Yes |
| 82 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 32472 | -0.845 | -0.5679 | Yes |
| 83 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 32540 | -0.860 | -0.5625 | Yes |
| 84 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 32609 | -0.877 | -0.5570 | Yes |
| 85 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 33049 | -0.997 | -0.5606 | Yes |
| 86 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 33162 | -1.031 | -0.5550 | Yes |
| 87 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 33338 | -1.089 | -0.5506 | Yes |
| 88 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 33365 | -1.097 | -0.5422 | Yes |
| 89 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 33411 | -1.112 | -0.5341 | Yes |
| 90 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 33654 | -1.195 | -0.5307 | Yes |
| 91 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 33893 | -1.277 | -0.5264 | Yes |
| 92 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 34035 | -1.323 | -0.5192 | Yes |
| 93 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 34117 | -1.353 | -0.5101 | Yes |
| 94 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 34141 | -1.363 | -0.4993 | Yes |
| 95 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 34668 | -1.581 | -0.5003 | Yes |
| 96 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 34858 | -1.668 | -0.4915 | Yes |
| 97 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 34916 | -1.697 | -0.4789 | Yes |
| 98 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 34941 | -1.706 | -0.4653 | Yes |
| 99 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 34978 | -1.728 | -0.4518 | Yes |
| 100 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 35012 | -1.747 | -0.4381 | Yes |
| 101 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 35020 | -1.749 | -0.4237 | Yes |
| 102 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 35049 | -1.767 | -0.4097 | Yes |
| 103 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 35094 | -1.798 | -0.3959 | Yes |
| 104 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 35167 | -1.837 | -0.3825 | Yes |
| 105 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 35176 | -1.844 | -0.3673 | Yes |
| 106 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 35242 | -1.885 | -0.3533 | Yes |
| 107 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 35320 | -1.929 | -0.3393 | Yes |
| 108 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 35334 | -1.937 | -0.3235 | Yes |
| 109 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 35432 | -1.999 | -0.3094 | Yes |
| 110 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 35490 | -2.041 | -0.2939 | Yes |
| 111 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 35504 | -2.052 | -0.2771 | Yes |
| 112 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 35505 | -2.053 | -0.2600 | Yes |
| 113 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 35511 | -2.057 | -0.2429 | Yes |
| 114 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 35561 | -2.093 | -0.2268 | Yes |
| 115 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 35609 | -2.126 | -0.2103 | Yes |
| 116 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 35753 | -2.228 | -0.1956 | Yes |
| 117 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 35781 | -2.252 | -0.1775 | Yes |
| 118 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 35942 | -2.406 | -0.1617 | Yes |
| 119 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 35943 | -2.407 | -0.1416 | Yes |
| 120 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 35959 | -2.420 | -0.1218 | Yes |
| 121 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 36211 | -2.669 | -0.1063 | Yes |
| 122 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 36328 | -2.830 | -0.0858 | Yes |
| 123 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 36362 | -2.870 | -0.0627 | Yes |
| 124 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36406 | -2.907 | -0.0396 | Yes |
| 125 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36636 | -3.260 | -0.0186 | Yes |
| 126 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36874 | -3.693 | 0.0058 | Yes |
