Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.70412326 |
| Normalized Enrichment Score (NES) | -1.4675997 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03945823 |
| FWER p-Value | 0.138 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 135 | 3.797 | 0.0197 | No |
| 2 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 178 | 3.553 | 0.0403 | No |
| 3 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 347 | 2.717 | 0.0525 | No |
| 4 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 451 | 2.410 | 0.0645 | No |
| 5 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 775 | 1.781 | 0.0667 | No |
| 6 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 849 | 1.693 | 0.0751 | No |
| 7 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 897 | 1.646 | 0.0839 | No |
| 8 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 1806 | 0.976 | 0.0654 | No |
| 9 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 2040 | 0.883 | 0.0645 | No |
| 10 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 2307 | 0.776 | 0.0621 | No |
| 11 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 2534 | 0.699 | 0.0602 | No |
| 12 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 4126 | 0.334 | 0.0193 | No |
| 13 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 4697 | 0.232 | 0.0053 | No |
| 14 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6515 | 0.000 | -0.0439 | No |
| 15 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7045 | 0.000 | -0.0582 | No |
| 16 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7318 | 0.000 | -0.0655 | No |
| 17 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 8062 | 0.000 | -0.0856 | No |
| 18 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8653 | 0.000 | -0.1016 | No |
| 19 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9044 | 0.000 | -0.1121 | No |
| 20 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9730 | 0.000 | -0.1307 | No |
| 21 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 9732 | 0.000 | -0.1307 | No |
| 22 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9830 | 0.000 | -0.1333 | No |
| 23 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10572 | 0.000 | -0.1534 | No |
| 24 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11369 | 0.000 | -0.1749 | No |
| 25 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12479 | 0.000 | -0.2049 | No |
| 26 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13339 | 0.000 | -0.2281 | No |
| 27 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 13814 | 0.000 | -0.2409 | No |
| 28 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14511 | 0.000 | -0.2597 | No |
| 29 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 15269 | 0.000 | -0.2802 | No |
| 30 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15982 | 0.000 | -0.2995 | No |
| 31 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 16643 | 0.000 | -0.3173 | No |
| 32 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17004 | 0.000 | -0.3271 | No |
| 33 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19639 | 0.000 | -0.3983 | No |
| 34 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 20121 | 0.000 | -0.4113 | No |
| 35 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21677 | 0.000 | -0.4534 | No |
| 36 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 23333 | 0.000 | -0.4981 | No |
| 37 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 23877 | 0.000 | -0.5128 | No |
| 38 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 24765 | 0.000 | -0.5368 | No |
| 39 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 25579 | 0.000 | -0.5588 | No |
| 40 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 27442 | -0.052 | -0.6088 | No |
| 41 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 27814 | -0.096 | -0.6183 | No |
| 42 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 28281 | -0.152 | -0.6300 | No |
| 43 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 29423 | -0.303 | -0.6590 | No |
| 44 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29558 | -0.319 | -0.6606 | No |
| 45 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 30065 | -0.389 | -0.6719 | No |
| 46 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 30505 | -0.454 | -0.6810 | No |
| 47 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 30582 | -0.467 | -0.6802 | No |
| 48 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 30776 | -0.496 | -0.6824 | No |
| 49 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 31159 | -0.558 | -0.6893 | No |
| 50 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 31163 | -0.559 | -0.6859 | No |
| 51 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 31273 | -0.575 | -0.6853 | No |
| 52 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 31304 | -0.579 | -0.6826 | No |
| 53 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 31614 | -0.639 | -0.6870 | No |
| 54 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 31619 | -0.640 | -0.6832 | No |
| 55 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 32083 | -0.751 | -0.6911 | No |
| 56 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 32565 | -0.865 | -0.6988 | Yes |
| 57 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 32674 | -0.898 | -0.6962 | Yes |
| 58 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32676 | -0.898 | -0.6907 | Yes |
| 59 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 32941 | -0.966 | -0.6919 | Yes |
| 60 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 32966 | -0.973 | -0.6866 | Yes |
| 61 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.6862 | Yes |
| 62 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 33399 | -1.109 | -0.6851 | Yes |
| 63 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 33509 | -1.145 | -0.6810 | Yes |
| 64 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 33617 | -1.180 | -0.6766 | Yes |
| 65 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.6697 | Yes |
| 66 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 33644 | -1.191 | -0.6627 | Yes |
| 67 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 33787 | -1.241 | -0.6589 | Yes |
| 68 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 33925 | -1.290 | -0.6547 | Yes |
| 69 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 34005 | -1.313 | -0.6488 | Yes |
| 70 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 34118 | -1.353 | -0.6435 | Yes |
| 71 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 34129 | -1.359 | -0.6355 | Yes |
| 72 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34135 | -1.361 | -0.6272 | Yes |
| 73 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 34175 | -1.380 | -0.6198 | Yes |
| 74 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 34217 | -1.397 | -0.6123 | Yes |
| 75 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 34243 | -1.407 | -0.6044 | Yes |
| 76 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 34308 | -1.437 | -0.5973 | Yes |
| 77 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 34327 | -1.445 | -0.5889 | Yes |
| 78 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 34824 | -1.652 | -0.5922 | Yes |
| 79 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 34952 | -1.712 | -0.5851 | Yes |
| 80 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 35012 | -1.747 | -0.5760 | Yes |
| 81 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 35128 | -1.813 | -0.5679 | Yes |
| 82 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 35233 | -1.881 | -0.5592 | Yes |
| 83 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 35295 | -1.917 | -0.5491 | Yes |
| 84 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 35344 | -1.943 | -0.5385 | Yes |
| 85 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 35346 | -1.944 | -0.5265 | Yes |
| 86 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35535 | -2.071 | -0.5189 | Yes |
| 87 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 35567 | -2.097 | -0.5069 | Yes |
| 88 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35607 | -2.123 | -0.4949 | Yes |
| 89 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.4820 | Yes |
| 90 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35912 | -2.379 | -0.4754 | Yes |
| 91 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 35950 | -2.410 | -0.4616 | Yes |
| 92 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 35954 | -2.417 | -0.4469 | Yes |
| 93 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 36045 | -2.498 | -0.4340 | Yes |
| 94 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36121 | -2.570 | -0.4202 | Yes |
| 95 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 36123 | -2.571 | -0.4045 | Yes |
| 96 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 36142 | -2.588 | -0.3891 | Yes |
| 97 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 36170 | -2.630 | -0.3736 | Yes |
| 98 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 36216 | -2.675 | -0.3584 | Yes |
| 99 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 36217 | -2.676 | -0.3420 | Yes |
| 100 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36333 | -2.835 | -0.3277 | Yes |
| 101 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36396 | -2.896 | -0.3116 | Yes |
| 102 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 36401 | -2.901 | -0.2939 | Yes |
| 103 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36404 | -2.906 | -0.2761 | Yes |
| 104 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36408 | -2.907 | -0.2584 | Yes |
| 105 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36416 | -2.915 | -0.2406 | Yes |
| 106 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 36463 | -2.984 | -0.2236 | Yes |
| 107 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 36550 | -3.111 | -0.2068 | Yes |
| 108 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36596 | -3.195 | -0.1884 | Yes |
| 109 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36602 | -3.206 | -0.1688 | Yes |
| 110 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36642 | -3.270 | -0.1498 | Yes |
| 111 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.1298 | Yes |
| 112 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36717 | -3.397 | -0.1108 | Yes |
| 113 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36846 | -3.630 | -0.0920 | Yes |
| 114 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36903 | -3.816 | -0.0701 | Yes |
| 115 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.0467 | Yes |
| 116 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 36967 | -4.026 | -0.0234 | Yes |
| 117 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37042 | -4.354 | 0.0013 | Yes |
