Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.7391908 |
| Normalized Enrichment Score (NES) | -1.5715008 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0033718161 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 114 | 3.942 | 0.0177 | No |
| 2 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 205 | 3.343 | 0.0329 | No |
| 3 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 366 | 2.648 | 0.0426 | No |
| 4 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 570 | 2.140 | 0.0484 | No |
| 5 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 593 | 2.090 | 0.0588 | No |
| 6 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 765 | 1.794 | 0.0637 | No |
| 7 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 1167 | 1.372 | 0.0601 | No |
| 8 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 3017 | 0.561 | 0.0130 | No |
| 9 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 3157 | 0.527 | 0.0120 | No |
| 10 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 3541 | 0.446 | 0.0040 | No |
| 11 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 4956 | 0.190 | -0.0332 | No |
| 12 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 5157 | 0.159 | -0.0378 | No |
| 13 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 5462 | 0.113 | -0.0454 | No |
| 14 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 5518 | 0.107 | -0.0464 | No |
| 15 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 6012 | 0.031 | -0.0595 | No |
| 16 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 6134 | 0.011 | -0.0627 | No |
| 17 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6573 | 0.000 | -0.0746 | No |
| 18 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 7931 | 0.000 | -0.1113 | No |
| 19 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9540 | 0.000 | -0.1548 | No |
| 20 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10414 | 0.000 | -0.1784 | No |
| 21 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 11871 | 0.000 | -0.2178 | No |
| 22 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12374 | 0.000 | -0.2314 | No |
| 23 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12520 | 0.000 | -0.2353 | No |
| 24 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 12531 | 0.000 | -0.2356 | No |
| 25 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12563 | 0.000 | -0.2364 | No |
| 26 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12823 | 0.000 | -0.2434 | No |
| 27 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13406 | 0.000 | -0.2592 | No |
| 28 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14657 | 0.000 | -0.2930 | No |
| 29 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15982 | 0.000 | -0.3288 | No |
| 30 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16210 | 0.000 | -0.3350 | No |
| 31 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16283 | 0.000 | -0.3369 | No |
| 32 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16426 | 0.000 | -0.3408 | No |
| 33 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16524 | 0.000 | -0.3434 | No |
| 34 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17452 | 0.000 | -0.3685 | No |
| 35 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18630 | 0.000 | -0.4003 | No |
| 36 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18631 | 0.000 | -0.4003 | No |
| 37 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 18885 | 0.000 | -0.4072 | No |
| 38 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19545 | 0.000 | -0.4250 | No |
| 39 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19686 | 0.000 | -0.4288 | No |
| 40 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 20241 | 0.000 | -0.4438 | No |
| 41 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 20927 | 0.000 | -0.4623 | No |
| 42 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21158 | 0.000 | -0.4685 | No |
| 43 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21677 | 0.000 | -0.4825 | No |
| 44 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 23840 | 0.000 | -0.5410 | No |
| 45 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 24036 | 0.000 | -0.5463 | No |
| 46 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 24343 | 0.000 | -0.5546 | No |
| 47 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 25355 | 0.000 | -0.5819 | No |
| 48 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 27510 | -0.059 | -0.6399 | No |
| 49 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 27562 | -0.065 | -0.6409 | No |
| 50 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 27694 | -0.081 | -0.6441 | No |
| 51 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 28421 | -0.170 | -0.6628 | No |
| 52 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 28511 | -0.184 | -0.6642 | No |
| 53 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 28978 | -0.243 | -0.6756 | No |
| 54 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 29235 | -0.278 | -0.6810 | No |
| 55 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 29488 | -0.312 | -0.6862 | No |
| 56 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29558 | -0.319 | -0.6864 | No |
| 57 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 30222 | -0.411 | -0.7021 | No |
| 58 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 30514 | -0.456 | -0.7076 | No |
| 59 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 30718 | -0.485 | -0.7105 | No |
| 60 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 30870 | -0.510 | -0.7119 | No |
| 61 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31228 | -0.569 | -0.7186 | No |
| 62 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 31565 | -0.630 | -0.7244 | No |
| 63 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 31619 | -0.640 | -0.7224 | No |
| 64 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 31715 | -0.659 | -0.7215 | No |
| 65 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 31841 | -0.688 | -0.7213 | No |
| 66 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31976 | -0.723 | -0.7211 | No |
| 67 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 32087 | -0.753 | -0.7201 | No |
| 68 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 32678 | -0.899 | -0.7313 | No |
| 69 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 32805 | -0.927 | -0.7298 | No |
| 70 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 33153 | -1.028 | -0.7338 | Yes |
| 71 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.7292 | Yes |
| 72 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 33364 | -1.096 | -0.7281 | Yes |
| 73 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 33400 | -1.109 | -0.7232 | Yes |
| 74 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.7231 | Yes |
| 75 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 33636 | -1.189 | -0.7170 | Yes |
| 76 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 33679 | -1.204 | -0.7118 | Yes |
| 77 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34054 | -1.329 | -0.7149 | Yes |
| 78 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 34129 | -1.359 | -0.7097 | Yes |
| 79 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34209 | -1.394 | -0.7045 | Yes |
| 80 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 34233 | -1.404 | -0.6977 | Yes |
| 81 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 34332 | -1.446 | -0.6927 | Yes |
| 82 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 34391 | -1.471 | -0.6865 | Yes |
| 83 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34573 | -1.544 | -0.6833 | Yes |
| 84 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 34859 | -1.668 | -0.6822 | Yes |
| 85 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 34968 | -1.723 | -0.6760 | Yes |
| 86 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35250 | -1.890 | -0.6736 | Yes |
| 87 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 35328 | -1.932 | -0.6655 | Yes |
| 88 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35535 | -2.071 | -0.6602 | Yes |
| 89 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35565 | -2.097 | -0.6499 | Yes |
| 90 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.6399 | Yes |
| 91 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 35750 | -2.224 | -0.6319 | Yes |
| 92 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 35810 | -2.280 | -0.6214 | Yes |
| 93 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35898 | -2.368 | -0.6113 | Yes |
| 94 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35912 | -2.379 | -0.5991 | Yes |
| 95 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 36043 | -2.495 | -0.5894 | Yes |
| 96 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36287 | -2.764 | -0.5814 | Yes |
| 97 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.5675 | Yes |
| 98 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36333 | -2.835 | -0.5527 | Yes |
| 99 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36346 | -2.850 | -0.5380 | Yes |
| 100 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 36383 | -2.888 | -0.5237 | Yes |
| 101 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36404 | -2.906 | -0.5089 | Yes |
| 102 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36408 | -2.907 | -0.4936 | Yes |
| 103 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36416 | -2.915 | -0.4784 | Yes |
| 104 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.4638 | Yes |
| 105 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 36463 | -2.984 | -0.4482 | Yes |
| 106 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36465 | -2.988 | -0.4324 | Yes |
| 107 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36475 | -3.005 | -0.4168 | Yes |
| 108 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36495 | -3.045 | -0.4013 | Yes |
| 109 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36540 | -3.100 | -0.3861 | Yes |
| 110 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36573 | -3.161 | -0.3703 | Yes |
| 111 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36581 | -3.173 | -0.3537 | Yes |
| 112 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36602 | -3.206 | -0.3373 | Yes |
| 113 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36626 | -3.241 | -0.3208 | Yes |
| 114 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.3041 | Yes |
| 115 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36658 | -3.299 | -0.2869 | Yes |
| 116 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36674 | -3.329 | -0.2697 | Yes |
| 117 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36677 | -3.335 | -0.2522 | Yes |
| 118 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36685 | -3.345 | -0.2347 | Yes |
| 119 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36693 | -3.364 | -0.2172 | Yes |
| 120 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36704 | -3.383 | -0.1996 | Yes |
| 121 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36785 | -3.510 | -0.1832 | Yes |
| 122 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36864 | -3.667 | -0.1659 | Yes |
| 123 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1466 | Yes |
| 124 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.1274 | Yes |
| 125 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36915 | -3.854 | -0.1072 | Yes |
| 126 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36973 | -4.041 | -0.0874 | Yes |
| 127 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36993 | -4.108 | -0.0662 | Yes |
| 128 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 37026 | -4.242 | -0.0447 | Yes |
| 129 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37042 | -4.354 | -0.0221 | Yes |
| 130 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 37055 | -4.428 | 0.0009 | Yes |
