Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P130_DN.V1_UP |
| Enrichment Score (ES) | -0.6272335 |
| Normalized Enrichment Score (NES) | -1.3217919 |
| Nominal p-value | 0.023913043 |
| FDR q-value | 0.16044234 |
| FWER p-Value | 0.942 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 96 | 4.072 | 0.0268 | No |
| 2 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 232 | 3.191 | 0.0463 | No |
| 3 | HMGA2 | high mobility group AT-hook 2 [Source:HGNC Symbol;Acc:HGNC:5009] | 300 | 2.873 | 0.0652 | No |
| 4 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 406 | 2.528 | 0.0807 | No |
| 5 | COL11A2 | collagen type XI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2187] | 596 | 2.085 | 0.0906 | No |
| 6 | FST | follistatin [Source:HGNC Symbol;Acc:HGNC:3971] | 798 | 1.750 | 0.0978 | No |
| 7 | LITAF | lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841] | 861 | 1.679 | 0.1083 | No |
| 8 | PPP1R15B | protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951] | 1019 | 1.523 | 0.1151 | No |
| 9 | QTRT1 | queuine tRNA-ribosyltransferase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:23797] | 1159 | 1.380 | 0.1213 | No |
| 10 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 1353 | 1.231 | 0.1250 | No |
| 11 | FAM220A | family with sequence similarity 220 member A [Source:HGNC Symbol;Acc:HGNC:22422] | 1883 | 0.951 | 0.1175 | No |
| 12 | TRAF2 | TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032] | 2044 | 0.882 | 0.1196 | No |
| 13 | CASP7 | caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508] | 2545 | 0.695 | 0.1111 | No |
| 14 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:811] | 2594 | 0.682 | 0.1147 | No |
| 15 | LSM4 | LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17259] | 3109 | 0.537 | 0.1047 | No |
| 16 | AVP | arginine vasopressin [Source:HGNC Symbol;Acc:HGNC:894] | 4153 | 0.328 | 0.0788 | No |
| 17 | ZBTB17 | zinc finger and BTB domain containing 17 [Source:HGNC Symbol;Acc:HGNC:12936] | 4296 | 0.299 | 0.0772 | No |
| 18 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153] | 4346 | 0.289 | 0.0779 | No |
| 19 | CYBA | cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577] | 4437 | 0.274 | 0.0775 | No |
| 20 | RIPK3 | receptor interacting serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:10021] | 4493 | 0.263 | 0.0779 | No |
| 21 | ZNF428 | zinc finger protein 428 [Source:HGNC Symbol;Acc:HGNC:20804] | 4503 | 0.262 | 0.0795 | No |
| 22 | PDZK1 | PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:8821] | 4623 | 0.243 | 0.0781 | No |
| 23 | GPN3 | GPN-loop GTPase 3 [Source:HGNC Symbol;Acc:HGNC:30186] | 5893 | 0.052 | 0.0441 | No |
| 24 | MRAS | muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227] | 6014 | 0.031 | 0.0411 | No |
| 25 | C11orf71 | chromosome 11 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:25937] | 6245 | 0.000 | 0.0349 | No |
| 26 | VSIG2 | V-set and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17149] | 6356 | 0.000 | 0.0319 | No |
| 27 | MYOZ2 | myozenin 2 [Source:HGNC Symbol;Acc:HGNC:1330] | 6359 | 0.000 | 0.0318 | No |
| 28 | USP13 | ubiquitin specific peptidase 13 [Source:HGNC Symbol;Acc:HGNC:12611] | 6467 | 0.000 | 0.0289 | No |
| 29 | FGF10 | fibroblast growth factor 10 [Source:HGNC Symbol;Acc:HGNC:3666] | 6763 | 0.000 | 0.0210 | No |
| 30 | AQP5 | aquaporin 5 [Source:HGNC Symbol;Acc:HGNC:638] | 6914 | 0.000 | 0.0169 | No |
| 31 | ART1 | ADP-ribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:723] | 7301 | 0.000 | 0.0065 | No |
| 32 | GREM2 | gremlin 2, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:17655] | 8054 | 0.000 | -0.0139 | No |
| 33 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8196 | 0.000 | -0.0177 | No |
| 34 | SIM2 | SIM bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10883] | 8197 | 0.000 | -0.0177 | No |
| 35 | B4GALT4 | beta-1,4-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:927] | 9495 | 0.000 | -0.0528 | No |
| 36 | PIWIL1 | piwi like RNA-mediated gene silencing 1 [Source:HGNC Symbol;Acc:HGNC:9007] | 9677 | 0.000 | -0.0577 | No |
| 37 | SLC22A3 | solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967] | 10036 | 0.000 | -0.0674 | No |
| 38 | FAM187A | family with sequence similarity 187 member A [Source:HGNC Symbol;Acc:HGNC:35153] | 10642 | 0.000 | -0.0837 | No |
| 39 | CRLF1 | cytokine receptor like factor 1 [Source:HGNC Symbol;Acc:HGNC:2364] | 10755 | 0.000 | -0.0868 | No |
| 40 | NKD2 | NKD inhibitor of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:17046] | 11096 | 0.000 | -0.0960 | No |
| 41 | MYLK | myosin light chain kinase [Source:HGNC Symbol;Acc:HGNC:7590] | 14280 | 0.000 | -0.1821 | No |
| 42 | NXNL1 | nucleoredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:25179] | 14701 | 0.000 | -0.1934 | No |
| 43 | RHOJ | ras homolog family member J [Source:HGNC Symbol;Acc:HGNC:688] | 14959 | 0.000 | -0.2004 | No |
| 44 | GC | GC vitamin D binding protein [Source:HGNC Symbol;Acc:HGNC:4187] | 16125 | 0.000 | -0.2319 | No |
| 45 | PCSK5 | proprotein convertase subtilisin/kexin type 5 [Source:HGNC Symbol;Acc:HGNC:8747] | 16221 | 0.000 | -0.2345 | No |
| 46 | SLC7A9 | solute carrier family 7 member 9 [Source:HGNC Symbol;Acc:HGNC:11067] | 16691 | 0.000 | -0.2472 | No |
| 47 | CRTAC1 | cartilage acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:14882] | 16830 | 0.000 | -0.2509 | No |
| 48 | TEAD1 | TEA domain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11714] | 17080 | 0.000 | -0.2576 | No |
| 49 | TWIST2 | twist family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:20670] | 17173 | 0.000 | -0.2601 | No |
| 50 | TINAG | tubulointerstitial nephritis antigen [Source:HGNC Symbol;Acc:HGNC:14599] | 17207 | 0.000 | -0.2610 | No |
| 51 | KAZN | kazrin, periplakin interacting protein [Source:HGNC Symbol;Acc:HGNC:29173] | 17300 | 0.000 | -0.2635 | No |
| 52 | SEMA5B | semaphorin 5B [Source:HGNC Symbol;Acc:HGNC:10737] | 17755 | 0.000 | -0.2758 | No |
| 53 | NKX2-8 | NK2 homeobox 8 [Source:HGNC Symbol;Acc:HGNC:16364] | 19069 | 0.000 | -0.3113 | No |
| 54 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 19875 | 0.000 | -0.3331 | No |
| 55 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20524 | 0.000 | -0.3506 | No |
| 56 | RSPH9 | radial spoke head component 9 [Source:HGNC Symbol;Acc:HGNC:21057] | 22176 | 0.000 | -0.3953 | No |
| 57 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 22693 | 0.000 | -0.4093 | No |
| 58 | FOXI1 | forkhead box I1 [Source:HGNC Symbol;Acc:HGNC:3815] | 23327 | 0.000 | -0.4264 | No |
| 59 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 23397 | 0.000 | -0.4283 | No |
| 60 | SULT1B1 | sulfotransferase family 1B member 1 [Source:HGNC Symbol;Acc:HGNC:17845] | 23771 | 0.000 | -0.4383 | No |
| 61 | CRB3 | crumbs cell polarity complex component 3 [Source:HGNC Symbol;Acc:HGNC:20237] | 23856 | 0.000 | -0.4406 | No |
| 62 | WNT2B | Wnt family member 2B [Source:HGNC Symbol;Acc:HGNC:12781] | 24526 | 0.000 | -0.4587 | No |
| 63 | SPATA13 | spermatogenesis associated 13 [Source:HGNC Symbol;Acc:HGNC:23222] | 24763 | 0.000 | -0.4651 | No |
| 64 | STMN3 | stathmin 3 [Source:HGNC Symbol;Acc:HGNC:15926] | 26742 | 0.000 | -0.5186 | No |
| 65 | ALK | ALK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:427] | 26914 | 0.000 | -0.5232 | No |
| 66 | RENBP | renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959] | 27225 | -0.015 | -0.5315 | No |
| 67 | EXOSC2 | exosome component 2 [Source:HGNC Symbol;Acc:HGNC:17097] | 27384 | -0.042 | -0.5355 | No |
| 68 | DUSP13 | dual specificity phosphatase 13 [Source:HGNC Symbol;Acc:HGNC:19681] | 27568 | -0.065 | -0.5400 | No |
| 69 | MIGA2 | mitoguardin 2 [Source:HGNC Symbol;Acc:HGNC:23621] | 27860 | -0.103 | -0.5471 | No |
| 70 | SLC13A2 | solute carrier family 13 member 2 [Source:HGNC Symbol;Acc:HGNC:10917] | 27884 | -0.105 | -0.5470 | No |
| 71 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 28092 | -0.128 | -0.5516 | No |
| 72 | SNN | stannin [Source:HGNC Symbol;Acc:HGNC:11149] | 28110 | -0.129 | -0.5512 | No |
| 73 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 28280 | -0.152 | -0.5546 | No |
| 74 | HINT1 | histidine triad nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4912] | 28712 | -0.211 | -0.5648 | No |
| 75 | GLIS2 | GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450] | 28997 | -0.245 | -0.5707 | No |
| 76 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 29838 | -0.357 | -0.5908 | No |
| 77 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 30381 | -0.433 | -0.6024 | No |
| 78 | CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 [Source:HGNC Symbol;Acc:HGNC:28314] | 30475 | -0.448 | -0.6016 | No |
| 79 | EFTUD2 | elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858] | 30698 | -0.482 | -0.6042 | No |
| 80 | MBD3 | methyl-CpG binding domain protein 3 [Source:HGNC Symbol;Acc:HGNC:6918] | 30703 | -0.483 | -0.6008 | No |
| 81 | EIF1B | eukaryotic translation initiation factor 1B [Source:HGNC Symbol;Acc:HGNC:30792] | 31212 | -0.566 | -0.6104 | No |
| 82 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 31564 | -0.630 | -0.6154 | No |
| 83 | STAT5B | signal transducer and activator of transcription 5B [Source:HGNC Symbol;Acc:HGNC:11367] | 31736 | -0.663 | -0.6152 | No |
| 84 | ELOF1 | elongation factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:28691] | 31897 | -0.705 | -0.6144 | No |
| 85 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32241 | -0.783 | -0.6180 | No |
| 86 | SDF2L1 | stromal cell derived factor 2 like 1 [Source:HGNC Symbol;Acc:HGNC:10676] | 32353 | -0.811 | -0.6152 | No |
| 87 | RASA4 | RAS p21 protein activator 4 [Source:HGNC Symbol;Acc:HGNC:23181] | 32663 | -0.896 | -0.6171 | No |
| 88 | POLR2I | RNA polymerase II subunit I [Source:HGNC Symbol;Acc:HGNC:9196] | 32936 | -0.965 | -0.6175 | No |
| 89 | RUVBL2 | RuvB like AAA ATPase 2 [Source:HGNC Symbol;Acc:HGNC:10475] | 33064 | -1.001 | -0.6137 | No |
| 90 | CUEDC2 | CUE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28352] | 33567 | -1.162 | -0.6188 | Yes |
| 91 | PARS2 | prolyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30563] | 33571 | -1.164 | -0.6105 | Yes |
| 92 | ANAPC5 | anaphase promoting complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:15713] | 33749 | -1.230 | -0.6064 | Yes |
| 93 | CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28184] | 33855 | -1.264 | -0.6001 | Yes |
| 94 | OXLD1 | oxidoreductase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27901] | 33921 | -1.288 | -0.5925 | Yes |
| 95 | CARD19 | caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148] | 34219 | -1.397 | -0.5905 | Yes |
| 96 | MYG1 | MYG1 exonuclease [Source:HGNC Symbol;Acc:HGNC:17590] | 34273 | -1.420 | -0.5816 | Yes |
| 97 | GFER | growth factor, augmenter of liver regeneration [Source:HGNC Symbol;Acc:HGNC:4236] | 34352 | -1.454 | -0.5732 | Yes |
| 98 | ORC1 | origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487] | 34387 | -1.468 | -0.5635 | Yes |
| 99 | CMTM7 | CKLF like MARVEL transmembrane domain containing 7 [Source:HGNC Symbol;Acc:HGNC:19178] | 34544 | -1.533 | -0.5567 | Yes |
| 100 | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:29897] | 34551 | -1.535 | -0.5457 | Yes |
| 101 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.5348 | Yes |
| 102 | HYAL3 | hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] | 35014 | -1.747 | -0.5345 | Yes |
| 103 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 35063 | -1.780 | -0.5229 | Yes |
| 104 | GRTP1 | growth hormone regulated TBC protein 1 [Source:HGNC Symbol;Acc:HGNC:20310] | 35183 | -1.847 | -0.5127 | Yes |
| 105 | POLD2 | DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176] | 35203 | -1.861 | -0.4998 | Yes |
| 106 | SELENOH | selenoprotein H [Source:HGNC Symbol;Acc:HGNC:18251] | 35475 | -2.031 | -0.4925 | Yes |
| 107 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 35542 | -2.076 | -0.4792 | Yes |
| 108 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.4680 | Yes |
| 109 | ABCG4 | ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884] | 35770 | -2.238 | -0.4532 | Yes |
| 110 | SGSM3 | small G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:25228] | 35792 | -2.263 | -0.4375 | Yes |
| 111 | SEMA6B | semaphorin 6B [Source:HGNC Symbol;Acc:HGNC:10739] | 36070 | -2.521 | -0.4267 | Yes |
| 112 | COQ8A | coenzyme Q8A [Source:HGNC Symbol;Acc:HGNC:16812] | 36166 | -2.625 | -0.4103 | Yes |
| 113 | SLC43A3 | solute carrier family 43 member 3 [Source:HGNC Symbol;Acc:HGNC:17466] | 36367 | -2.874 | -0.3949 | Yes |
| 114 | ICA1 | islet cell autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:5343] | 36384 | -2.889 | -0.3745 | Yes |
| 115 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36421 | -2.926 | -0.3543 | Yes |
| 116 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.3353 | Yes |
| 117 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.3134 | Yes |
| 118 | FADS2 | fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] | 36686 | -3.346 | -0.2916 | Yes |
| 119 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36732 | -3.413 | -0.2682 | Yes |
| 120 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36735 | -3.416 | -0.2435 | Yes |
| 121 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36797 | -3.534 | -0.2196 | Yes |
| 122 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36798 | -3.535 | -0.1941 | Yes |
| 123 | PIMREG | PICALM interacting mitotic regulator [Source:HGNC Symbol;Acc:HGNC:25483] | 36828 | -3.593 | -0.1689 | Yes |
| 124 | TRAF4 | TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034] | 36833 | -3.613 | -0.1428 | Yes |
| 125 | ZBTB12 | zinc finger and BTB domain containing 12 [Source:HGNC Symbol;Acc:HGNC:19066] | 36919 | -3.863 | -0.1172 | Yes |
| 126 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36957 | -3.986 | -0.0894 | Yes |
| 127 | SNTA1 | syntrophin alpha 1 [Source:HGNC Symbol;Acc:HGNC:11167] | 36984 | -4.075 | -0.0606 | Yes |
| 128 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36989 | -4.101 | -0.0311 | Yes |
| 129 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37079 | -4.675 | 0.0003 | Yes |
