Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | DESCARTES_FETAL_SPLEEN_MYELOID_CELLS |
| Enrichment Score (ES) | 0.610902 |
| Normalized Enrichment Score (NES) | 1.6290547 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0659809 |
| FWER p-Value | 0.233 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 0 | 5.000 | 0.0468 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.995 | 0.0936 | Yes |
| 3 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 10 | 4.929 | 0.1395 | Yes |
| 4 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 69 | 4.312 | 0.1783 | Yes |
| 5 | NLRP3 | NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400] | 105 | 4.021 | 0.2150 | Yes |
| 6 | MNDA | myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183] | 130 | 3.833 | 0.2503 | Yes |
| 7 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 154 | 3.685 | 0.2842 | Yes |
| 8 | ADAP2 | ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487] | 179 | 3.540 | 0.3167 | Yes |
| 9 | RGS1 | regulator of G protein signaling 1 [Source:HGNC Symbol;Acc:HGNC:9991] | 188 | 3.476 | 0.3490 | Yes |
| 10 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 201 | 3.397 | 0.3805 | Yes |
| 11 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 226 | 3.208 | 0.4099 | Yes |
| 12 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 275 | 2.999 | 0.4366 | Yes |
| 13 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 410 | 2.520 | 0.4566 | Yes |
| 14 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 440 | 2.432 | 0.4786 | Yes |
| 15 | NABP1 | nucleic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26232] | 553 | 2.169 | 0.4959 | Yes |
| 16 | RASSF4 | Ras association domain family member 4 [Source:HGNC Symbol;Acc:HGNC:20793] | 602 | 2.075 | 0.5140 | Yes |
| 17 | CD274 | CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635] | 650 | 1.994 | 0.5314 | Yes |
| 18 | KCNAB1 | potassium voltage-gated channel subfamily A member regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6228] | 685 | 1.936 | 0.5486 | Yes |
| 19 | LY96 | lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156] | 760 | 1.801 | 0.5635 | Yes |
| 20 | PID1 | phosphotyrosine interaction domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26084] | 1316 | 1.257 | 0.5602 | Yes |
| 21 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1327 | 1.250 | 0.5717 | Yes |
| 22 | NOD2 | nucleotide binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:5331] | 1346 | 1.237 | 0.5828 | Yes |
| 23 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1381 | 1.214 | 0.5932 | Yes |
| 24 | SMIM35 | small integral membrane protein 35 [Source:HGNC Symbol;Acc:HGNC:44179] | 1482 | 1.153 | 0.6013 | Yes |
| 25 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1615 | 1.080 | 0.6078 | Yes |
| 26 | THEMIS2 | thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839] | 1837 | 0.966 | 0.6109 | Yes |
| 27 | NCF2 | neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661] | 2633 | 0.671 | 0.5957 | No |
| 28 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 2793 | 0.619 | 0.5972 | No |
| 29 | FABP5 | fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560] | 3348 | 0.483 | 0.5867 | No |
| 30 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 4126 | 0.334 | 0.5688 | No |
| 31 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4225 | 0.313 | 0.5691 | No |
| 32 | ITGAX | integrin subunit alpha X [Source:HGNC Symbol;Acc:HGNC:6152] | 4535 | 0.257 | 0.5632 | No |
| 33 | CDS1 | CDP-diacylglycerol synthase 1 [Source:HGNC Symbol;Acc:HGNC:1800] | 4538 | 0.256 | 0.5655 | No |
| 34 | ITGAD | integrin subunit alpha D [Source:HGNC Symbol;Acc:HGNC:6146] | 4557 | 0.254 | 0.5674 | No |
| 35 | ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:3357] | 5194 | 0.154 | 0.5516 | No |
| 36 | TMEM63C | transmembrane protein 63C [Source:HGNC Symbol;Acc:HGNC:23787] | 5837 | 0.059 | 0.5348 | No |
| 37 | VSIG4 | V-set and immunoglobulin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:17032] | 6358 | 0.000 | 0.5207 | No |
| 38 | LINC01645 | long intergenic non-protein coding RNA 1645 [Source:HGNC Symbol;Acc:HGNC:52432] | 7114 | 0.000 | 0.5003 | No |
| 39 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7568 | 0.000 | 0.4881 | No |
| 40 | EPB41L3 | erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380] | 7834 | 0.000 | 0.4809 | No |
| 41 | RASGEF1C | RasGEF domain family member 1C [Source:HGNC Symbol;Acc:HGNC:27400] | 8045 | 0.000 | 0.4752 | No |
| 42 | FCAR | Fc fragment of IgA receptor [Source:HGNC Symbol;Acc:HGNC:3608] | 8145 | 0.000 | 0.4725 | No |
| 43 | FCN1 | ficolin 1 [Source:HGNC Symbol;Acc:HGNC:3623] | 8217 | 0.000 | 0.4706 | No |
| 44 | AL606970.3 | novel transcript | 8221 | 0.000 | 0.4705 | No |
| 45 | BATF3 | basic leucine zipper ATF-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:28915] | 8665 | 0.000 | 0.4585 | No |
| 46 | CLEC7A | C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558] | 9354 | 0.000 | 0.4399 | No |
| 47 | ADGRE4P | adhesion G protein-coupled receptor E4, pseudogene [Source:HGNC Symbol;Acc:HGNC:19240] | 10421 | 0.000 | 0.4111 | No |
| 48 | CHN2 | chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944] | 10487 | 0.000 | 0.4093 | No |
| 49 | IGSF21 | immunoglobin superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:28246] | 10768 | 0.000 | 0.4018 | No |
| 50 | MS4A7 | membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378] | 10906 | 0.000 | 0.3981 | No |
| 51 | S100Z | S100 calcium binding protein Z [Source:HGNC Symbol;Acc:HGNC:30367] | 11493 | 0.000 | 0.3822 | No |
| 52 | CLNK | cytokine dependent hematopoietic cell linker [Source:HGNC Symbol;Acc:HGNC:17438] | 11495 | 0.000 | 0.3822 | No |
| 53 | SIGLEC16 | sialic acid binding Ig like lectin 16 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:24851] | 11695 | 0.000 | 0.3768 | No |
| 54 | CSF2RA | colony stimulating factor 2 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:2435] | 11770 | 0.000 | 0.3748 | No |
| 55 | AGR2 | anterior gradient 2, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:328] | 11917 | 0.000 | 0.3708 | No |
| 56 | LINC00996 | long intergenic non-protein coding RNA 996 [Source:HGNC Symbol;Acc:HGNC:27800] | 11919 | 0.000 | 0.3708 | No |
| 57 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12398 | 0.000 | 0.3579 | No |
| 58 | LILRA5 | leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309] | 13360 | 0.000 | 0.3319 | No |
| 59 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13363 | 0.000 | 0.3318 | No |
| 60 | LILRB2 | leukocyte immunoglobulin like receptor B2 [Source:HGNC Symbol;Acc:HGNC:6606] | 13364 | 0.000 | 0.3318 | No |
| 61 | LILRB3 | leukocyte immunoglobulin like receptor B3 [Source:HGNC Symbol;Acc:HGNC:6607] | 13365 | 0.000 | 0.3318 | No |
| 62 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13366 | 0.000 | 0.3318 | No |
| 63 | LILRB5 | leukocyte immunoglobulin like receptor B5 [Source:HGNC Symbol;Acc:HGNC:6609] | 13367 | 0.000 | 0.3318 | No |
| 64 | MEGF11 | multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635] | 14236 | 0.000 | 0.3084 | No |
| 65 | EBI3 | Epstein-Barr virus induced 3 [Source:HGNC Symbol;Acc:HGNC:3129] | 14906 | 0.000 | 0.2903 | No |
| 66 | CD300LF | CD300 molecule like family member f [Source:HGNC Symbol;Acc:HGNC:29883] | 15799 | 0.000 | 0.2661 | No |
| 67 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15850 | 0.000 | 0.2648 | No |
| 68 | NEXMIF | neurite extension and migration factor [Source:HGNC Symbol;Acc:HGNC:29433] | 16012 | 0.000 | 0.2604 | No |
| 69 | TIMD4 | T cell immunoglobulin and mucin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25132] | 16199 | 0.000 | 0.2554 | No |
| 70 | RN7SL138P | RNA, 7SL, cytoplasmic 138, pseudogene [Source:HGNC Symbol;Acc:HGNC:46154] | 18296 | 0.000 | 0.1987 | No |
| 71 | MRO | maestro [Source:HGNC Symbol;Acc:HGNC:24121] | 18945 | 0.000 | 0.1811 | No |
| 72 | RUFY4 | RUN and FYVE domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24804] | 20065 | 0.000 | 0.1509 | No |
| 73 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 20070 | 0.000 | 0.1508 | No |
| 74 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 22205 | 0.000 | 0.0930 | No |
| 75 | DSCAM-IT1 | DSCAM intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41327] | 22464 | 0.000 | 0.0861 | No |
| 76 | CLEC9A | C-type lectin domain containing 9A [Source:HGNC Symbol;Acc:HGNC:26705] | 22814 | 0.000 | 0.0766 | No |
| 77 | CD163L1 | CD163 molecule like 1 [Source:HGNC Symbol;Acc:HGNC:30375] | 23695 | 0.000 | 0.0528 | No |
| 78 | SIGLEC7 | sialic acid binding Ig like lectin 7 [Source:HGNC Symbol;Acc:HGNC:10876] | 23853 | 0.000 | 0.0486 | No |
| 79 | NRIR | negative regulator of interferon response [Source:HGNC Symbol;Acc:HGNC:51269] | 23920 | 0.000 | 0.0468 | No |
| 80 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 24094 | 0.000 | 0.0421 | No |
| 81 | EYA2 | EYA transcriptional coactivator and phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3520] | 24147 | 0.000 | 0.0407 | No |
| 82 | NCKAP5 | NCK associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29847] | 24161 | 0.000 | 0.0403 | No |
| 83 | PDCD1LG2 | programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731] | 25238 | 0.000 | 0.0112 | No |
| 84 | CCDC170 | coiled-coil domain containing 170 [Source:HGNC Symbol;Acc:HGNC:21177] | 25655 | 0.000 | -0.0000 | No |
| 85 | MS4A4E | membrane spanning 4-domains A4E [Source:HGNC Symbol;Acc:HGNC:14284] | 25701 | 0.000 | -0.0012 | No |
| 86 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 25706 | 0.000 | -0.0013 | No |
| 87 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 25713 | 0.000 | -0.0015 | No |
| 88 | SPIC | Spi-C transcription factor [Source:HGNC Symbol;Acc:HGNC:29549] | 26005 | 0.000 | -0.0094 | No |
| 89 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 26429 | 0.000 | -0.0208 | No |
| 90 | OSCAR | osteoclast associated Ig-like receptor [Source:HGNC Symbol;Acc:HGNC:29960] | 26694 | 0.000 | -0.0280 | No |
| 91 | SIRPB2 | signal regulatory protein beta 2 [Source:HGNC Symbol;Acc:HGNC:16247] | 26710 | 0.000 | -0.0284 | No |
| 92 | DSCAM | DS cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:3039] | 27096 | 0.000 | -0.0388 | No |
| 93 | TRIM36 | tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280] | 27179 | -0.006 | -0.0409 | No |
| 94 | NAIP | NLR family apoptosis inhibitory protein [Source:HGNC Symbol;Acc:HGNC:7634] | 27349 | -0.038 | -0.0452 | No |
| 95 | MERTK | MER proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7027] | 27588 | -0.068 | -0.0510 | No |
| 96 | PRAM1 | PML-RARA regulated adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:30091] | 27603 | -0.070 | -0.0507 | No |
| 97 | ANKRD24 | ankyrin repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:29424] | 27713 | -0.084 | -0.0529 | No |
| 98 | ZNF415P1 | zinc finger protein 415 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49869] | 27922 | -0.109 | -0.0575 | No |
| 99 | FMN1 | formin 1 [Source:HGNC Symbol;Acc:HGNC:3768] | 27954 | -0.114 | -0.0572 | No |
| 100 | KCNMA1 | potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284] | 28081 | -0.126 | -0.0595 | No |
| 101 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 28092 | -0.128 | -0.0585 | No |
| 102 | CABP4 | calcium binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1386] | 28149 | -0.134 | -0.0588 | No |
| 103 | CD200R1 | CD200 receptor 1 [Source:HGNC Symbol;Acc:HGNC:24235] | 28179 | -0.138 | -0.0583 | No |
| 104 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 29319 | -0.291 | -0.0864 | No |
| 105 | GHRL | ghrelin and obestatin prepropeptide [Source:HGNC Symbol;Acc:HGNC:18129] | 29582 | -0.322 | -0.0905 | No |
| 106 | FAM20A | FAM20A golgi associated secretory pathway pseudokinase [Source:HGNC Symbol;Acc:HGNC:23015] | 29760 | -0.346 | -0.0920 | No |
| 107 | CARD14 | caspase recruitment domain family member 14 [Source:HGNC Symbol;Acc:HGNC:16446] | 30458 | -0.445 | -0.1067 | No |
| 108 | TRPV4 | transient receptor potential cation channel subfamily V member 4 [Source:HGNC Symbol;Acc:HGNC:18083] | 31063 | -0.542 | -0.1180 | No |
| 109 | RAB39A | RAB39A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16521] | 31120 | -0.550 | -0.1143 | No |
| 110 | MKNK1 | MAPK interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:7110] | 32090 | -0.753 | -0.1335 | No |
| 111 | HK3 | hexokinase 3 [Source:HGNC Symbol;Acc:HGNC:4925] | 32108 | -0.757 | -0.1269 | No |
| 112 | PPARG | peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] | 32553 | -0.862 | -0.1308 | No |
| 113 | GPR137B | G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862] | 33255 | -1.065 | -0.1398 | No |
| 114 | DMXL2 | Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938] | 33424 | -1.116 | -0.1339 | No |
| 115 | IGSF6 | immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953] | 33760 | -1.233 | -0.1314 | No |
| 116 | FLVCR2 | FLVCR heme transporter 2 [Source:HGNC Symbol;Acc:HGNC:20105] | 33793 | -1.244 | -0.1206 | No |
| 117 | ALMS1P1 | ALMS1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:29586] | 34364 | -1.461 | -0.1224 | No |
| 118 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 34696 | -1.590 | -0.1164 | No |
| 119 | MCOLN1 | mucolipin 1 [Source:HGNC Symbol;Acc:HGNC:13356] | 34912 | -1.695 | -0.1064 | No |
| 120 | LRRK1 | leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608] | 34925 | -1.700 | -0.0908 | No |
| 121 | SIRPB1 | signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928] | 35314 | -1.924 | -0.0832 | No |
| 122 | ZNF710 | zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352] | 35519 | -2.061 | -0.0695 | No |
| 123 | KCNK13 | potassium two pore domain channel subfamily K member 13 [Source:HGNC Symbol;Acc:HGNC:6275] | 35571 | -2.098 | -0.0512 | No |
| 124 | WWP1 | WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:17004] | 36172 | -2.631 | -0.0428 | No |
| 125 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36695 | -3.366 | -0.0254 | No |
| 126 | SLC8A1 | solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068] | 36914 | -3.851 | 0.0048 | No |
