Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | CHR17Q12 |
| Enrichment Score (ES) | 0.52415496 |
| Normalized Enrichment Score (NES) | 1.3535563 |
| Nominal p-value | 0.0091743115 |
| FDR q-value | 0.4507648 |
| FWER p-Value | 0.754 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.875 | 0.0562 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 16 | 4.731 | 0.1106 | Yes |
| 3 | SLFN5 | schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286] | 54 | 4.048 | 0.1564 | Yes |
| 4 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 57 | 4.042 | 0.2030 | Yes |
| 5 | SLFN13 | schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481] | 180 | 3.132 | 0.2359 | Yes |
| 6 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 366 | 2.436 | 0.2590 | Yes |
| 7 | SLFN11 | schlafen family member 11 [Source:HGNC Symbol;Acc:HGNC:26633] | 393 | 2.383 | 0.2859 | Yes |
| 8 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 480 | 2.145 | 0.3083 | Yes |
| 9 | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821] | 486 | 2.127 | 0.3328 | Yes |
| 10 | STARD3 | StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579] | 862 | 1.556 | 0.3406 | Yes |
| 11 | DHRS11 | dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639] | 970 | 1.450 | 0.3545 | Yes |
| 12 | NLE1 | notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889] | 1012 | 1.422 | 0.3698 | Yes |
| 13 | CWC25 | CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989] | 1022 | 1.417 | 0.3859 | Yes |
| 14 | MYO19 | myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234] | 1215 | 1.275 | 0.3955 | Yes |
| 15 | AP2B1 | adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563] | 1227 | 1.268 | 0.4098 | Yes |
| 16 | UNC45B | unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304] | 1266 | 1.239 | 0.4231 | Yes |
| 17 | CDK12 | cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224] | 1502 | 1.104 | 0.4295 | Yes |
| 18 | PGAP3 | post-GPI attachment to proteins phospholipase 3 [Source:HGNC Symbol;Acc:HGNC:23719] | 1511 | 1.102 | 0.4420 | Yes |
| 19 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1556 | 1.085 | 0.4534 | Yes |
| 20 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 1603 | 1.067 | 0.4645 | Yes |
| 21 | ZNHIT3 | zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309] | 1715 | 1.018 | 0.4732 | Yes |
| 22 | PIGW | phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213] | 1834 | 0.970 | 0.4812 | Yes |
| 23 | MIEN1 | migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230] | 1873 | 0.956 | 0.4913 | Yes |
| 24 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 1943 | 0.921 | 0.5000 | Yes |
| 25 | AATF | apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235] | 2342 | 0.772 | 0.4982 | Yes |
| 26 | PSMB3 | proteasome 20S subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540] | 2495 | 0.726 | 0.5024 | Yes |
| 27 | ZNF830 | zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291] | 2524 | 0.717 | 0.5100 | Yes |
| 28 | FBXO47 | F-box protein 47 [Source:HGNC Symbol;Acc:HGNC:31969] | 2637 | 0.684 | 0.5148 | Yes |
| 29 | TCAP | titin-cap [Source:HGNC Symbol;Acc:HGNC:11610] | 2913 | 0.611 | 0.5145 | Yes |
| 30 | LIG3 | DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600] | 2914 | 0.611 | 0.5215 | Yes |
| 31 | SNORD7 | small nucleolar RNA, C/D box 7 [Source:HGNC Symbol;Acc:HGNC:32704] | 3064 | 0.576 | 0.5242 | Yes |
| 32 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 3511 | 0.478 | 0.5176 | No |
| 33 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3833 | 0.417 | 0.5138 | No |
| 34 | E2F3P1 | E2F transcription factor 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:3116] | 4068 | 0.378 | 0.5118 | No |
| 35 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 4195 | 0.357 | 0.5125 | No |
| 36 | GGNBP2 | gametogenetin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19357] | 4579 | 0.297 | 0.5056 | No |
| 37 | C17orf50 | chromosome 17 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:29581] | 4662 | 0.286 | 0.5067 | No |
| 38 | SOCS7 | suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846] | 4833 | 0.258 | 0.5050 | No |
| 39 | YWHAEP7 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:49437] | 5109 | 0.215 | 0.5001 | No |
| 40 | SRCIN1 | SRC kinase signaling inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:29506] | 5365 | 0.175 | 0.4952 | No |
| 41 | RPL19 | ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:10312] | 6205 | 0.063 | 0.4732 | No |
| 42 | EPOP | elongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493] | 6413 | 0.037 | 0.4681 | No |
| 43 | LHX1 | LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6593] | 6685 | 0.005 | 0.4608 | No |
| 44 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6745 | 0.000 | 0.4592 | No |
| 45 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6746 | 0.000 | 0.4592 | No |
| 46 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6747 | 0.000 | 0.4592 | No |
| 47 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6767 | 0.000 | 0.4587 | No |
| 48 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6770 | 0.000 | 0.4586 | No |
| 49 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6772 | 0.000 | 0.4586 | No |
| 50 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6776 | 0.000 | 0.4585 | No |
| 51 | TBC1D3 | TBC1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:19031] | 7919 | 0.000 | 0.4276 | No |
| 52 | LYZL6 | lysozyme like 6 [Source:HGNC Symbol;Acc:HGNC:29614] | 8228 | 0.000 | 0.4193 | No |
| 53 | ASIC2 | acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99] | 8280 | 0.000 | 0.4179 | No |
| 54 | MIR2909 | microRNA 2909 [Source:HGNC Symbol;Acc:HGNC:38372] | 9439 | 0.000 | 0.3866 | No |
| 55 | RASL10B | RAS like family 10 member B [Source:HGNC Symbol;Acc:HGNC:30295] | 10107 | 0.000 | 0.3685 | No |
| 56 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 10172 | 0.000 | 0.3668 | No |
| 57 | AA06 | uncharacterized LOC100506677 [Source:NCBI gene (formerly Entrezgene);Acc:100506677] | 10466 | 0.000 | 0.3589 | No |
| 58 | PNMT | phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160] | 10839 | 0.000 | 0.3488 | No |
| 59 | C17orf78 | chromosome 17 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:26831] | 12000 | 0.000 | 0.3174 | No |
| 60 | C17orf98 | chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492] | 12022 | 0.000 | 0.3169 | No |
| 61 | SNHG30 | small nucleolar RNA host gene 30 [Source:HGNC Symbol;Acc:HGNC:52836] | 12447 | 0.000 | 0.3054 | No |
| 62 | SLFN14 | schlafen family member 14 [Source:HGNC Symbol;Acc:HGNC:32689] | 12503 | 0.000 | 0.3039 | No |
| 63 | RNU6-1192P | RNA, U6 small nuclear 1192, pseudogene [Source:HGNC Symbol;Acc:HGNC:48155] | 13112 | 0.000 | 0.2874 | No |
| 64 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14919 | 0.000 | 0.2386 | No |
| 65 | SLC35G3 | solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848] | 16043 | 0.000 | 0.2082 | No |
| 66 | RN7SL301P | RNA, 7SL, cytoplasmic 301, pseudogene [Source:HGNC Symbol;Acc:HGNC:46317] | 16117 | 0.000 | 0.2062 | No |
| 67 | SNORA21 | small nucleolar RNA, H/ACA box 21 [Source:HGNC Symbol;Acc:HGNC:32611] | 16193 | 0.000 | 0.2042 | No |
| 68 | C17orf102 | chromosome 17 open reading frame 102 [Source:HGNC Symbol;Acc:HGNC:34412] | 16653 | 0.000 | 0.1918 | No |
| 69 | RNU6-866P | RNA, U6 small nuclear 866, pseudogene [Source:HGNC Symbol;Acc:HGNC:47829] | 17119 | 0.000 | 0.1792 | No |
| 70 | RNA5SP440 | RNA, 5S ribosomal pseudogene 440 [Source:HGNC Symbol;Acc:HGNC:43340] | 17331 | 0.000 | 0.1735 | No |
| 71 | RNA5SP439 | RNA, 5S ribosomal pseudogene 439 [Source:HGNC Symbol;Acc:HGNC:43339] | 17365 | 0.000 | 0.1726 | No |
| 72 | RNA5SP438 | RNA, 5S ribosomal pseudogene 438 [Source:HGNC Symbol;Acc:HGNC:43338] | 17366 | 0.000 | 0.1726 | No |
| 73 | CCL15-CCL14 | CCL15-CCL14 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44436] | 17477 | 0.000 | 0.1696 | No |
| 74 | HNF1B | HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630] | 17635 | 0.000 | 0.1654 | No |
| 75 | PPP1R1B | protein phosphatase 1 regulatory inhibitor subunit 1B [Source:HGNC Symbol;Acc:HGNC:9287] | 17674 | 0.000 | 0.1643 | No |
| 76 | LRRC37A9P | leucine rich repeat containing 37 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:43813] | 17718 | 0.000 | 0.1632 | No |
| 77 | RNU6-489P | RNA, U6 small nuclear 489, pseudogene [Source:HGNC Symbol;Acc:HGNC:47452] | 18495 | 0.000 | 0.1422 | No |
| 78 | RNU6-233P | RNA, U6 small nuclear 233, pseudogene [Source:HGNC Symbol;Acc:HGNC:47196] | 18894 | 0.000 | 0.1314 | No |
| 79 | NEUROD2 | neuronal differentiation 2 [Source:HGNC Symbol;Acc:HGNC:7763] | 19241 | 0.000 | 0.1220 | No |
| 80 | LINC01989 | long intergenic non-protein coding RNA 1989 [Source:HGNC Symbol;Acc:HGNC:52821] | 20351 | 0.000 | 0.0920 | No |
| 81 | HEATR9 | HEAT repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:26548] | 21571 | 0.000 | 0.0591 | No |
| 82 | LINC02079 | long intergenic non-protein coding RNA 2079 [Source:HGNC Symbol;Acc:HGNC:52927] | 21670 | 0.000 | 0.0564 | No |
| 83 | TBC1D3K | TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245] | 22290 | 0.000 | 0.0397 | No |
| 84 | TBC1D3L | TBC1 domain family member 3L [Source:HGNC Symbol;Acc:HGNC:51246] | 22291 | 0.000 | 0.0397 | No |
| 85 | TBC1D3B | TBC1 domain family member 3B [Source:HGNC Symbol;Acc:HGNC:27011] | 22296 | 0.000 | 0.0395 | No |
| 86 | TBC1D3E | TBC1 domain family member 3E [Source:HGNC Symbol;Acc:HGNC:27071] | 22298 | 0.000 | 0.0395 | No |
| 87 | TBC1D3F | TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257] | 22299 | 0.000 | 0.0395 | No |
| 88 | TBC1D3C | TBC1 domain family member 3C [Source:HGNC Symbol;Acc:HGNC:24889] | 22301 | 0.000 | 0.0395 | No |
| 89 | TBC1D3D | TBC1 domain family member 3D [Source:HGNC Symbol;Acc:HGNC:28944] | 22302 | 0.000 | 0.0395 | No |
| 90 | TBC1D3I | TBC1 domain family member 3I [Source:HGNC Symbol;Acc:HGNC:32709] | 22303 | 0.000 | 0.0395 | No |
| 91 | TBC1D3J | TBC1 domain family member 3J [Source:HGNC Symbol;Acc:HGNC:51247] | 22305 | 0.000 | 0.0395 | No |
| 92 | TBC1D3G | TBC1 domain family member 3G [Source:HGNC Symbol;Acc:HGNC:29860] | 22307 | 0.000 | 0.0394 | No |
| 93 | TBC1D3H | TBC1 domain family member 3H [Source:HGNC Symbol;Acc:HGNC:30708] | 22308 | 0.000 | 0.0394 | No |
| 94 | TMEM132E | transmembrane protein 132E [Source:HGNC Symbol;Acc:HGNC:26991] | 22534 | 0.000 | 0.0334 | No |
| 95 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22918 | 0.000 | 0.0230 | No |
| 96 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22920 | 0.000 | 0.0230 | No |
| 97 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22927 | 0.000 | 0.0228 | No |
| 98 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22928 | 0.000 | 0.0228 | No |
| 99 | FNDC8 | fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286] | 25861 | 0.000 | -0.0565 | No |
| 100 | RNU6-840P | RNA, U6 small nuclear 840, pseudogene [Source:HGNC Symbol;Acc:HGNC:47803] | 25964 | 0.000 | -0.0593 | No |
| 101 | GAS2L2 | growth arrest specific 2 like 2 [Source:HGNC Symbol;Acc:HGNC:24846] | 26787 | 0.000 | -0.0815 | No |
| 102 | MIR4734 | microRNA 4734 [Source:HGNC Symbol;Acc:HGNC:41572] | 27202 | 0.000 | -0.0927 | No |
| 103 | MIR4726 | microRNA 4726 [Source:HGNC Symbol;Acc:HGNC:41722] | 27218 | 0.000 | -0.0931 | No |
| 104 | MIR4728 | microRNA 4728 [Source:HGNC Symbol;Acc:HGNC:41632] | 27221 | 0.000 | -0.0932 | No |
| 105 | MIR4727 | microRNA 4727 [Source:HGNC Symbol;Acc:HGNC:41709] | 27222 | 0.000 | -0.0932 | No |
| 106 | LRRC37A11P | leucine rich repeat containing 37 member A11, pseudogene [Source:HGNC Symbol;Acc:HGNC:43815] | 27475 | 0.000 | -0.1000 | No |
| 107 | TOMM20P2 | TOMM20 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50519] | 28875 | -0.175 | -0.1358 | No |
| 108 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 28905 | -0.178 | -0.1346 | No |
| 109 | RPL23 | ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316] | 29383 | -0.235 | -0.1448 | No |
| 110 | ARHGAP23 | Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293] | 29458 | -0.247 | -0.1439 | No |
| 111 | MRM1 | mitochondrial rRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26202] | 29611 | -0.267 | -0.1449 | No |
| 112 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 29694 | -0.277 | -0.1440 | No |
| 113 | LINC00672 | long intergenic non-protein coding RNA 672 [Source:HGNC Symbol;Acc:HGNC:44353] | 29835 | -0.292 | -0.1444 | No |
| 114 | CISD3 | CDGSH iron sulfur domain 3 [Source:HGNC Symbol;Acc:HGNC:27578] | 31637 | -0.555 | -0.1867 | No |
| 115 | ARL5C | ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111] | 31669 | -0.559 | -0.1811 | No |
| 116 | PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:8998] | 31684 | -0.562 | -0.1750 | No |
| 117 | HMGB1P24 | high mobility group box 1 pseudogene 24 [Source:HGNC Symbol;Acc:HGNC:39115] | 31696 | -0.563 | -0.1687 | No |
| 118 | MLLT6 | MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138] | 32845 | -0.803 | -0.1905 | No |
| 119 | SYNRG | synergin gamma [Source:HGNC Symbol;Acc:HGNC:557] | 33047 | -0.854 | -0.1861 | No |
| 120 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 34272 | -1.206 | -0.2053 | No |
| 121 | ACACA | acetyl-CoA carboxylase alpha [Source:HGNC Symbol;Acc:HGNC:84] | 34398 | -1.252 | -0.1942 | No |
| 122 | MMP28 | matrix metallopeptidase 28 [Source:HGNC Symbol;Acc:HGNC:14366] | 34466 | -1.279 | -0.1812 | No |
| 123 | GPR179 | G protein-coupled receptor 179 [Source:HGNC Symbol;Acc:HGNC:31371] | 34646 | -1.347 | -0.1705 | No |
| 124 | RDM1 | RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950] | 34679 | -1.362 | -0.1556 | No |
| 125 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34721 | -1.384 | -0.1407 | No |
| 126 | TADA2A | transcriptional adaptor 2A [Source:HGNC Symbol;Acc:HGNC:11531] | 34890 | -1.468 | -0.1283 | No |
| 127 | DDX52 | DExD-box helicase 52 [Source:HGNC Symbol;Acc:HGNC:20038] | 35750 | -1.964 | -0.1289 | No |
| 128 | PLXDC1 | plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945] | 35869 | -2.055 | -0.1083 | No |
| 129 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] | 35916 | -2.096 | -0.0853 | No |
| 130 | PCGF2 | polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929] | 36583 | -2.806 | -0.0709 | No |
| 131 | FBXL20 | F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679] | 36929 | -3.578 | -0.0389 | No |
| 132 | STAC2 | SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990] | 36972 | -3.743 | 0.0032 | No |
