Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.87938356 |
| Normalized Enrichment Score (NES) | 2.1898048 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 21 | 4.639 | 0.0423 | Yes |
| 2 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 48 | 4.133 | 0.0797 | Yes |
| 3 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 62 | 3.994 | 0.1163 | Yes |
| 4 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 63 | 3.992 | 0.1531 | Yes |
| 5 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 77 | 3.799 | 0.1879 | Yes |
| 6 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 85 | 3.724 | 0.2221 | Yes |
| 7 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 86 | 3.723 | 0.2564 | Yes |
| 8 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 93 | 3.654 | 0.2900 | Yes |
| 9 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 101 | 3.606 | 0.3231 | Yes |
| 10 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 103 | 3.595 | 0.3563 | Yes |
| 11 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 106 | 3.571 | 0.3892 | Yes |
| 12 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 114 | 3.467 | 0.4211 | Yes |
| 13 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 133 | 3.364 | 0.4517 | Yes |
| 14 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 143 | 3.299 | 0.4819 | Yes |
| 15 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 184 | 3.113 | 0.5095 | Yes |
| 16 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 206 | 3.020 | 0.5369 | Yes |
| 17 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 220 | 2.934 | 0.5636 | Yes |
| 18 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 236 | 2.845 | 0.5895 | Yes |
| 19 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 246 | 2.791 | 0.6150 | Yes |
| 20 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 281 | 2.657 | 0.6386 | Yes |
| 21 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 285 | 2.640 | 0.6629 | Yes |
| 22 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 288 | 2.633 | 0.6872 | Yes |
| 23 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 317 | 2.547 | 0.7099 | Yes |
| 24 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 395 | 2.373 | 0.7298 | Yes |
| 25 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 397 | 2.367 | 0.7516 | Yes |
| 26 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 414 | 2.311 | 0.7725 | Yes |
| 27 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 557 | 1.990 | 0.7870 | Yes |
| 28 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 615 | 1.895 | 0.8030 | Yes |
| 29 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 657 | 1.811 | 0.8186 | Yes |
| 30 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 755 | 1.679 | 0.8315 | Yes |
| 31 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 981 | 1.443 | 0.8387 | Yes |
| 32 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 1115 | 1.352 | 0.8476 | Yes |
| 33 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 1340 | 1.184 | 0.8525 | Yes |
| 34 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 1446 | 1.128 | 0.8601 | Yes |
| 35 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 1571 | 1.078 | 0.8667 | Yes |
| 36 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 1723 | 1.015 | 0.8720 | Yes |
| 37 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1789 | 0.992 | 0.8794 | Yes |
| 38 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 2593 | 0.696 | 0.8641 | No |
| 39 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 2641 | 0.682 | 0.8691 | No |
| 40 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 3194 | 0.547 | 0.8593 | No |
| 41 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 3306 | 0.522 | 0.8611 | No |
| 42 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 3705 | 0.440 | 0.8544 | No |
| 43 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 4423 | 0.319 | 0.8380 | No |
| 44 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4730 | 0.275 | 0.8322 | No |
| 45 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 4837 | 0.257 | 0.8317 | No |
| 46 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 4881 | 0.250 | 0.8329 | No |
| 47 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 5017 | 0.228 | 0.8313 | No |
| 48 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 5249 | 0.194 | 0.8269 | No |
| 49 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 6481 | 0.031 | 0.7939 | No |
| 50 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 7564 | 0.000 | 0.7647 | No |
| 51 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 8091 | 0.000 | 0.7505 | No |
| 52 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9525 | 0.000 | 0.7117 | No |
| 53 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 10194 | 0.000 | 0.6937 | No |
| 54 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10519 | 0.000 | 0.6849 | No |
| 55 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10801 | 0.000 | 0.6773 | No |
| 56 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12416 | 0.000 | 0.6337 | No |
| 57 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12712 | 0.000 | 0.6257 | No |
| 58 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12715 | 0.000 | 0.6257 | No |
| 59 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13301 | 0.000 | 0.6099 | No |
| 60 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15932 | 0.000 | 0.5388 | No |
| 61 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17183 | 0.000 | 0.5050 | No |
| 62 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17802 | 0.000 | 0.4883 | No |
| 63 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 18944 | 0.000 | 0.4574 | No |
| 64 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19429 | 0.000 | 0.4444 | No |
| 65 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19814 | 0.000 | 0.4340 | No |
| 66 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 20084 | 0.000 | 0.4267 | No |
| 67 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 20100 | 0.000 | 0.4263 | No |
| 68 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 20646 | 0.000 | 0.4116 | No |
| 69 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 20659 | 0.000 | 0.4113 | No |
| 70 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 20839 | 0.000 | 0.4064 | No |
| 71 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 22080 | 0.000 | 0.3729 | No |
| 72 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 22093 | 0.000 | 0.3726 | No |
| 73 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 22682 | 0.000 | 0.3567 | No |
| 74 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22918 | 0.000 | 0.3503 | No |
| 75 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22927 | 0.000 | 0.3501 | No |
| 76 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 23289 | 0.000 | 0.3404 | No |
| 77 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 23898 | 0.000 | 0.3239 | No |
| 78 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 23978 | 0.000 | 0.3218 | No |
| 79 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24539 | 0.000 | 0.3067 | No |
| 80 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 24794 | 0.000 | 0.2998 | No |
| 81 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 25932 | 0.000 | 0.2691 | No |
| 82 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 26055 | 0.000 | 0.2658 | No |
| 83 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27252 | 0.000 | 0.2334 | No |
| 84 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 28991 | -0.189 | 0.1882 | No |
| 85 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 29152 | -0.207 | 0.1858 | No |
| 86 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 29554 | -0.260 | 0.1774 | No |
| 87 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 29711 | -0.279 | 0.1757 | No |
| 88 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 29765 | -0.284 | 0.1769 | No |
| 89 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 29910 | -0.300 | 0.1758 | No |
| 90 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 31554 | -0.541 | 0.1364 | No |
| 91 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 32089 | -0.630 | 0.1277 | No |
| 92 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 32837 | -0.801 | 0.1149 | No |
