Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.8597519 |
| Normalized Enrichment Score (NES) | -1.6957622 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0016162181 |
| FWER p-Value | 0.018 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 5637 | 0.136 | -0.1507 | No |
| 2 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | -0.1634 | No |
| 3 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 22127 | 0.000 | -0.5951 | No |
| 4 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30480 | -0.375 | -0.8166 | No |
| 5 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 31026 | -0.458 | -0.8264 | No |
| 6 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 31715 | -0.565 | -0.8389 | No |
| 7 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 32260 | -0.666 | -0.8465 | No |
| 8 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32479 | -0.717 | -0.8447 | No |
| 9 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32680 | -0.764 | -0.8419 | No |
| 10 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 33264 | -0.912 | -0.8479 | No |
| 11 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.8480 | Yes |
| 12 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.8475 | Yes |
| 13 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 34120 | -1.149 | -0.8355 | Yes |
| 14 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34716 | -1.383 | -0.8367 | Yes |
| 15 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 34823 | -1.429 | -0.8243 | Yes |
| 16 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34852 | -1.446 | -0.8096 | Yes |
| 17 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 34892 | -1.469 | -0.7950 | Yes |
| 18 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34998 | -1.516 | -0.7816 | Yes |
| 19 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 35016 | -1.527 | -0.7657 | Yes |
| 20 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.7501 | Yes |
| 21 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35127 | -1.583 | -0.7352 | Yes |
| 22 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35128 | -1.584 | -0.7183 | Yes |
| 23 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35435 | -1.752 | -0.7078 | Yes |
| 24 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35561 | -1.824 | -0.6917 | Yes |
| 25 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.6735 | Yes |
| 26 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35643 | -1.882 | -0.6538 | Yes |
| 27 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35653 | -1.889 | -0.6338 | Yes |
| 28 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 35657 | -1.892 | -0.6137 | Yes |
| 29 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.5959 | Yes |
| 30 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35993 | -2.147 | -0.5785 | Yes |
| 31 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35994 | -2.147 | -0.5555 | Yes |
| 32 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.5326 | Yes |
| 33 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36026 | -2.171 | -0.5101 | Yes |
| 34 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36068 | -2.206 | -0.4877 | Yes |
| 35 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.4646 | Yes |
| 36 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36153 | -2.285 | -0.4415 | Yes |
| 37 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36164 | -2.301 | -0.4172 | Yes |
| 38 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.3931 | Yes |
| 39 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36274 | -2.405 | -0.3696 | Yes |
| 40 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.3456 | Yes |
| 41 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36397 | -2.543 | -0.3185 | Yes |
| 42 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 36479 | -2.649 | -0.2924 | Yes |
| 43 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36551 | -2.763 | -0.2647 | Yes |
| 44 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.2360 | Yes |
| 45 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36636 | -2.885 | -0.2054 | Yes |
| 46 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36644 | -2.890 | -0.1747 | Yes |
| 47 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.1440 | Yes |
| 48 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36808 | -3.196 | -0.1133 | Yes |
| 49 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36816 | -3.214 | -0.0792 | Yes |
| 50 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36995 | -3.849 | -0.0428 | Yes |
| 51 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37054 | -4.241 | 0.0010 | Yes |
