Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | LEE_EARLY_T_LYMPHOCYTE_UP |
| Enrichment Score (ES) | -0.78373027 |
| Normalized Enrichment Score (NES) | -1.6671197 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.004774957 |
| FWER p-Value | 0.069 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RAPGEF5 | Rap guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:16862] | 744 | 1.692 | -0.0086 | No |
| 2 | AEBP1 | AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303] | 786 | 1.641 | 0.0014 | No |
| 3 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 1746 | 1.007 | -0.0176 | No |
| 4 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1757 | 1.003 | -0.0111 | No |
| 5 | SLC1A4 | solute carrier family 1 member 4 [Source:HGNC Symbol;Acc:HGNC:10942] | 1768 | 0.998 | -0.0046 | No |
| 6 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 1852 | 0.965 | -0.0002 | No |
| 7 | GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129] | 2335 | 0.776 | -0.0080 | No |
| 8 | PALLD | palladin, cytoskeletal associated protein [Source:HGNC Symbol;Acc:HGNC:17068] | 2879 | 0.619 | -0.0185 | No |
| 9 | LETM1 | leucine zipper and EF-hand containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6556] | 3912 | 0.405 | -0.0436 | No |
| 10 | GNA15 | G protein subunit alpha 15 [Source:HGNC Symbol;Acc:HGNC:4383] | 4059 | 0.380 | -0.0450 | No |
| 11 | NLGN4X | neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287] | 4471 | 0.314 | -0.0540 | No |
| 12 | FAIM | Fas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:18703] | 5337 | 0.180 | -0.0761 | No |
| 13 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 5637 | 0.136 | -0.0833 | No |
| 14 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 5978 | 0.090 | -0.0919 | No |
| 15 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | -0.0956 | No |
| 16 | MIR646HG | MIR646 host gene [Source:HGNC Symbol;Acc:HGNC:27659] | 8389 | 0.000 | -0.1565 | No |
| 17 | HHIP | hedgehog interacting protein [Source:HGNC Symbol;Acc:HGNC:14866] | 8462 | 0.000 | -0.1585 | No |
| 18 | TNFRSF21 | TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469] | 9565 | 0.000 | -0.1883 | No |
| 19 | PON1 | paraoxonase 1 [Source:HGNC Symbol;Acc:HGNC:9204] | 11099 | 0.000 | -0.2297 | No |
| 20 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12760 | 0.000 | -0.2746 | No |
| 21 | SCRN1 | secernin 1 [Source:HGNC Symbol;Acc:HGNC:22192] | 14277 | 0.000 | -0.3156 | No |
| 22 | MZB1 | marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125] | 14862 | 0.000 | -0.3314 | No |
| 23 | TMSB15A | thymosin beta 15a [Source:HGNC Symbol;Acc:HGNC:30744] | 17196 | 0.000 | -0.3945 | No |
| 24 | PALM2AKAP2 | PALM2 and AKAP2 fusion [Source:HGNC Symbol;Acc:HGNC:33529] | 17954 | 0.000 | -0.4149 | No |
| 25 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 19157 | 0.000 | -0.4474 | No |
| 26 | ARPP21 | cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968] | 20924 | 0.000 | -0.4952 | No |
| 27 | TSHR | thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373] | 22084 | 0.000 | -0.5265 | No |
| 28 | FAM72C | family with sequence similarity 72 member C [Source:HGNC Symbol;Acc:HGNC:30602] | 22365 | 0.000 | -0.5341 | No |
| 29 | CD1E | CD1e molecule [Source:HGNC Symbol;Acc:HGNC:1638] | 22972 | 0.000 | -0.5505 | No |
| 30 | CD1B | CD1b molecule [Source:HGNC Symbol;Acc:HGNC:1635] | 22975 | 0.000 | -0.5505 | No |
| 31 | CD1A | CD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634] | 22976 | 0.000 | -0.5505 | No |
| 32 | CD99 | CD99 molecule (Xg blood group) [Source:HGNC Symbol;Acc:HGNC:7082] | 23113 | 0.000 | -0.5542 | No |
| 33 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 23764 | 0.000 | -0.5718 | No |
| 34 | CRNDE | colorectal neoplasia differentially expressed [Source:HGNC Symbol;Acc:HGNC:37078] | 28012 | -0.069 | -0.6862 | No |
| 35 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 29922 | -0.301 | -0.7357 | No |
| 36 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 30362 | -0.359 | -0.7452 | No |
| 37 | LDLRAD4 | low density lipoprotein receptor class A domain containing 4 [Source:HGNC Symbol;Acc:HGNC:1224] | 30726 | -0.411 | -0.7522 | No |
| 38 | GSE1 | Gse1 coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:28979] | 30763 | -0.418 | -0.7503 | No |
| 39 | RCAN1 | regulator of calcineurin 1 [Source:HGNC Symbol;Acc:HGNC:3040] | 31016 | -0.457 | -0.7540 | No |
| 40 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.7696 | No |
| 41 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 32260 | -0.666 | -0.7792 | Yes |
| 42 | CENPW | centromere protein W [Source:HGNC Symbol;Acc:HGNC:21488] | 32288 | -0.674 | -0.7753 | Yes |
| 43 | DNTT | DNA nucleotidylexotransferase [Source:HGNC Symbol;Acc:HGNC:2983] | 32447 | -0.711 | -0.7748 | Yes |
| 44 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32450 | -0.711 | -0.7700 | Yes |
| 45 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32522 | -0.726 | -0.7670 | Yes |
| 46 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 32563 | -0.736 | -0.7631 | Yes |
| 47 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32901 | -0.817 | -0.7666 | Yes |
| 48 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 33288 | -0.920 | -0.7708 | Yes |
| 49 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33395 | -0.948 | -0.7672 | Yes |
| 50 | KNL1 | kinetochore scaffold 1 [Source:HGNC Symbol;Acc:HGNC:24054] | 33455 | -0.960 | -0.7623 | Yes |
| 51 | DIAPH3 | diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480] | 34006 | -1.116 | -0.7696 | Yes |
| 52 | RUFY3 | RUN and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30285] | 34228 | -1.190 | -0.7674 | Yes |
| 53 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7730 | Yes |
| 54 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 34834 | -1.438 | -0.7644 | Yes |
| 55 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 34907 | -1.473 | -0.7563 | Yes |
| 56 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.7496 | Yes |
| 57 | CEP128 | centrosomal protein 128 [Source:HGNC Symbol;Acc:HGNC:20359] | 35092 | -1.565 | -0.7401 | Yes |
| 58 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 35282 | -1.667 | -0.7339 | Yes |
| 59 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 35314 | -1.681 | -0.7233 | Yes |
| 60 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35320 | -1.686 | -0.7119 | Yes |
| 61 | LRR1 | leucine rich repeat protein 1 [Source:HGNC Symbol;Acc:HGNC:19742] | 35333 | -1.691 | -0.7008 | Yes |
| 62 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35401 | -1.734 | -0.6908 | Yes |
| 63 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35494 | -1.788 | -0.6811 | Yes |
| 64 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35520 | -1.803 | -0.6695 | Yes |
| 65 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35551 | -1.818 | -0.6580 | Yes |
| 66 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35561 | -1.824 | -0.6458 | Yes |
| 67 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35605 | -1.855 | -0.6344 | Yes |
| 68 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 35607 | -1.856 | -0.6218 | Yes |
| 69 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35614 | -1.860 | -0.6093 | Yes |
| 70 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.5969 | Yes |
| 71 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35633 | -1.871 | -0.5843 | Yes |
| 72 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35656 | -1.892 | -0.5720 | Yes |
| 73 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 35664 | -1.896 | -0.5593 | Yes |
| 74 | MPP1 | membrane palmitoylated protein 1 [Source:HGNC Symbol;Acc:HGNC:7219] | 35669 | -1.903 | -0.5465 | Yes |
| 75 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35681 | -1.914 | -0.5338 | Yes |
| 76 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.5231 | Yes |
| 77 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35789 | -1.990 | -0.5096 | Yes |
| 78 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 35841 | -2.029 | -0.4972 | Yes |
| 79 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 35901 | -2.086 | -0.4846 | Yes |
| 80 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 35970 | -2.128 | -0.4719 | Yes |
| 81 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.4584 | Yes |
| 82 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | 36022 | -2.169 | -0.4438 | Yes |
| 83 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36026 | -2.171 | -0.4291 | Yes |
| 84 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36035 | -2.183 | -0.4145 | Yes |
| 85 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36036 | -2.183 | -0.3997 | Yes |
| 86 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.3849 | Yes |
| 87 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 36076 | -2.214 | -0.3707 | Yes |
| 88 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36082 | -2.223 | -0.3558 | Yes |
| 89 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.3410 | Yes |
| 90 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36124 | -2.261 | -0.3262 | Yes |
| 91 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36160 | -2.294 | -0.3116 | Yes |
| 92 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36214 | -2.336 | -0.2971 | Yes |
| 93 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36261 | -2.395 | -0.2821 | Yes |
| 94 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.2678 | Yes |
| 95 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.2513 | Yes |
| 96 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36397 | -2.543 | -0.2341 | Yes |
| 97 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 36433 | -2.595 | -0.2174 | Yes |
| 98 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 36576 | -2.796 | -0.2022 | Yes |
| 99 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.1840 | Yes |
| 100 | CXXC5 | CXXC finger protein 5 [Source:HGNC Symbol;Acc:HGNC:26943] | 36665 | -2.935 | -0.1650 | Yes |
| 101 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.1452 | Yes |
| 102 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.1251 | Yes |
| 103 | E2F7 | E2F transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:23820] | 36800 | -3.180 | -0.1068 | Yes |
| 104 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36808 | -3.196 | -0.0853 | Yes |
| 105 | E2F2 | E2F transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3114] | 36862 | -3.322 | -0.0641 | Yes |
| 106 | TFDP2 | transcription factor Dp-2 [Source:HGNC Symbol;Acc:HGNC:11751] | 36874 | -3.364 | -0.0415 | Yes |
| 107 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36877 | -3.375 | -0.0186 | Yes |
| 108 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36930 | -3.582 | 0.0043 | Yes |
