Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.80094975 |
| Normalized Enrichment Score (NES) | -1.6940522 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.001616033 |
| FWER p-Value | 0.02 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1083 | 1.377 | -0.0189 | No |
| 2 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 1978 | 0.907 | -0.0362 | No |
| 3 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 2039 | 0.885 | -0.0312 | No |
| 4 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 2504 | 0.722 | -0.0383 | No |
| 5 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 3035 | 0.581 | -0.0482 | No |
| 6 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 3494 | 0.482 | -0.0570 | No |
| 7 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 5349 | 0.178 | -0.1058 | No |
| 8 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 5414 | 0.167 | -0.1062 | No |
| 9 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | -0.1251 | No |
| 10 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12760 | 0.000 | -0.3042 | No |
| 11 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 12854 | 0.000 | -0.3067 | No |
| 12 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16793 | 0.000 | -0.4131 | No |
| 13 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18447 | 0.000 | -0.4578 | No |
| 14 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 20299 | 0.000 | -0.5078 | No |
| 15 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27091 | 0.000 | -0.6914 | No |
| 16 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 28305 | -0.108 | -0.7233 | No |
| 17 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 28628 | -0.144 | -0.7309 | No |
| 18 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 28911 | -0.180 | -0.7372 | No |
| 19 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 29230 | -0.216 | -0.7442 | No |
| 20 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 29519 | -0.254 | -0.7501 | No |
| 21 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29642 | -0.271 | -0.7513 | No |
| 22 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 29922 | -0.301 | -0.7566 | No |
| 23 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 30168 | -0.333 | -0.7607 | No |
| 24 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 30362 | -0.359 | -0.7632 | No |
| 25 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30480 | -0.375 | -0.7635 | No |
| 26 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 30701 | -0.407 | -0.7664 | No |
| 27 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31617 | -0.551 | -0.7870 | No |
| 28 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 31715 | -0.565 | -0.7854 | No |
| 29 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 32260 | -0.666 | -0.7951 | No |
| 30 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32479 | -0.717 | -0.7955 | Yes |
| 31 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 32563 | -0.736 | -0.7922 | Yes |
| 32 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 32664 | -0.760 | -0.7892 | Yes |
| 33 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32757 | -0.782 | -0.7858 | Yes |
| 34 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 33164 | -0.884 | -0.7901 | Yes |
| 35 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33400 | -0.949 | -0.7893 | Yes |
| 36 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 33588 | -0.998 | -0.7869 | Yes |
| 37 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33638 | -1.014 | -0.7806 | Yes |
| 38 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 33639 | -1.014 | -0.7729 | Yes |
| 39 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.7661 | Yes |
| 40 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.7693 | Yes |
| 41 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34169 | -1.167 | -0.7620 | Yes |
| 42 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34224 | -1.190 | -0.7545 | Yes |
| 43 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 34253 | -1.199 | -0.7463 | Yes |
| 44 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 34317 | -1.222 | -0.7388 | Yes |
| 45 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 34364 | -1.240 | -0.7307 | Yes |
| 46 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 34501 | -1.292 | -0.7246 | Yes |
| 47 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34716 | -1.383 | -0.7200 | Yes |
| 48 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7113 | Yes |
| 49 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 35016 | -1.527 | -0.7059 | Yes |
| 50 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.6952 | Yes |
| 51 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35127 | -1.583 | -0.6853 | Yes |
| 52 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 35131 | -1.586 | -0.6734 | Yes |
| 53 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35408 | -1.739 | -0.6678 | Yes |
| 54 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35435 | -1.752 | -0.6553 | Yes |
| 55 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35520 | -1.803 | -0.6440 | Yes |
| 56 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35605 | -1.855 | -0.6323 | Yes |
| 57 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.6188 | Yes |
| 58 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35653 | -1.889 | -0.6053 | Yes |
| 59 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35698 | -1.925 | -0.5920 | Yes |
| 60 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.5794 | Yes |
| 61 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 35895 | -2.079 | -0.5666 | Yes |
| 62 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 35901 | -2.086 | -0.5510 | Yes |
| 63 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 35937 | -2.113 | -0.5361 | Yes |
| 64 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35994 | -2.147 | -0.5214 | Yes |
| 65 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.5052 | Yes |
| 66 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.4894 | Yes |
| 67 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36036 | -2.183 | -0.4736 | Yes |
| 68 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.4572 | Yes |
| 69 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36104 | -2.244 | -0.4420 | Yes |
| 70 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36160 | -2.294 | -0.4262 | Yes |
| 71 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36164 | -2.301 | -0.4089 | Yes |
| 72 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.3922 | Yes |
| 73 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36214 | -2.336 | -0.3752 | Yes |
| 74 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36274 | -2.405 | -0.3587 | Yes |
| 75 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.3422 | Yes |
| 76 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.3239 | Yes |
| 77 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36397 | -2.543 | -0.3048 | Yes |
| 78 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36522 | -2.718 | -0.2877 | Yes |
| 79 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 36594 | -2.820 | -0.2684 | Yes |
| 80 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.2476 | Yes |
| 81 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36636 | -2.885 | -0.2261 | Yes |
| 82 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36644 | -2.890 | -0.2045 | Yes |
| 83 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36645 | -2.892 | -0.1827 | Yes |
| 84 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.1613 | Yes |
| 85 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36690 | -2.980 | -0.1392 | Yes |
| 86 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36698 | -2.991 | -0.1169 | Yes |
| 87 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36808 | -3.196 | -0.0958 | Yes |
| 88 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36816 | -3.214 | -0.0717 | Yes |
| 89 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36860 | -3.318 | -0.0479 | Yes |
| 90 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36930 | -3.582 | -0.0228 | Yes |
| 91 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36936 | -3.599 | 0.0042 | Yes |
