Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.93309367 |
| Normalized Enrichment Score (NES) | 2.331827 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 1 | 4.920 | 0.0269 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 3 | 4.907 | 0.0538 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 24 | 4.568 | 0.0783 | Yes |
| 4 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 27 | 4.528 | 0.1031 | Yes |
| 5 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 33 | 4.396 | 0.1270 | Yes |
| 6 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 40 | 4.264 | 0.1502 | Yes |
| 7 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 43 | 4.212 | 0.1733 | Yes |
| 8 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 49 | 4.124 | 0.1957 | Yes |
| 9 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 57 | 4.042 | 0.2177 | Yes |
| 10 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 62 | 3.994 | 0.2395 | Yes |
| 11 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 102 | 3.599 | 0.2581 | Yes |
| 12 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 104 | 3.593 | 0.2778 | Yes |
| 13 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 107 | 3.570 | 0.2973 | Yes |
| 14 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 109 | 3.552 | 0.3168 | Yes |
| 15 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 110 | 3.541 | 0.3362 | Yes |
| 16 | RHOC | ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669] | 117 | 3.451 | 0.3549 | Yes |
| 17 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 122 | 3.444 | 0.3737 | Yes |
| 18 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 148 | 3.287 | 0.3910 | Yes |
| 19 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 150 | 3.268 | 0.4089 | Yes |
| 20 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 158 | 3.239 | 0.4265 | Yes |
| 21 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 161 | 3.226 | 0.4441 | Yes |
| 22 | CLEC4D | C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554] | 163 | 3.214 | 0.4617 | Yes |
| 23 | PNP | purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892] | 164 | 3.213 | 0.4793 | Yes |
| 24 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 176 | 3.143 | 0.4962 | Yes |
| 25 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 183 | 3.113 | 0.5131 | Yes |
| 26 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 188 | 3.087 | 0.5299 | Yes |
| 27 | GK | glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289] | 196 | 3.059 | 0.5465 | Yes |
| 28 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 197 | 3.054 | 0.5633 | Yes |
| 29 | STK10 | serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] | 203 | 3.029 | 0.5797 | Yes |
| 30 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 206 | 3.020 | 0.5962 | Yes |
| 31 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 210 | 2.969 | 0.6124 | Yes |
| 32 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 215 | 2.947 | 0.6285 | Yes |
| 33 | CFLAR | CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876] | 251 | 2.762 | 0.6426 | Yes |
| 34 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 289 | 2.631 | 0.6561 | Yes |
| 35 | LCP2 | lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529] | 325 | 2.530 | 0.6690 | Yes |
| 36 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 349 | 2.475 | 0.6819 | Yes |
| 37 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 364 | 2.441 | 0.6949 | Yes |
| 38 | MYO10 | myosin X [Source:HGNC Symbol;Acc:HGNC:7593] | 372 | 2.426 | 0.7080 | Yes |
| 39 | IFRD1 | interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] | 388 | 2.388 | 0.7207 | Yes |
| 40 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 416 | 2.309 | 0.7326 | Yes |
| 41 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 469 | 2.163 | 0.7431 | Yes |
| 42 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 476 | 2.149 | 0.7547 | Yes |
| 43 | IRGM | immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597] | 477 | 2.148 | 0.7665 | Yes |
| 44 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 480 | 2.145 | 0.7782 | Yes |
| 45 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 496 | 2.102 | 0.7893 | Yes |
| 46 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 522 | 2.042 | 0.7998 | Yes |
| 47 | HCLS1 | hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:HGNC:4844] | 538 | 2.027 | 0.8105 | Yes |
| 48 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 587 | 1.948 | 0.8199 | Yes |
| 49 | SLC20A1 | solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946] | 626 | 1.878 | 0.8292 | Yes |
| 50 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 630 | 1.872 | 0.8393 | Yes |
| 51 | ETF1 | eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:HGNC:3477] | 647 | 1.836 | 0.8490 | Yes |
| 52 | RNF11 | ring finger protein 11 [Source:HGNC Symbol;Acc:HGNC:10056] | 658 | 1.811 | 0.8586 | Yes |
| 53 | DEGS1 | delta 4-desaturase, sphingolipid 1 [Source:HGNC Symbol;Acc:HGNC:13709] | 717 | 1.730 | 0.8665 | Yes |
| 54 | SLC2A1 | solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005] | 779 | 1.646 | 0.8739 | Yes |
| 55 | CLN3 | CLN3 lysosomal/endosomal transmembrane protein, battenin [Source:HGNC Symbol;Acc:HGNC:2074] | 796 | 1.635 | 0.8824 | Yes |
| 56 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 871 | 1.549 | 0.8889 | Yes |
| 57 | EIF1 | eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249] | 975 | 1.447 | 0.8941 | Yes |
| 58 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 1164 | 1.314 | 0.8962 | Yes |
| 59 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 1171 | 1.309 | 0.9032 | Yes |
| 60 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 1185 | 1.302 | 0.9100 | Yes |
| 61 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 1294 | 1.218 | 0.9137 | Yes |
| 62 | MAP2K1 | mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840] | 1367 | 1.167 | 0.9182 | Yes |
| 63 | WSB1 | WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221] | 1464 | 1.120 | 0.9217 | Yes |
| 64 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1493 | 1.107 | 0.9270 | Yes |
| 65 | JUND | JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206] | 1577 | 1.077 | 0.9307 | Yes |
| 66 | TOP1 | DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986] | 1697 | 1.024 | 0.9331 | Yes |
| 67 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 1975 | 0.908 | 0.9306 | No |
| 68 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 3511 | 0.478 | 0.8917 | No |
| 69 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 5062 | 0.221 | 0.8511 | No |
| 70 | RCN1 | reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934] | 5271 | 0.190 | 0.8465 | No |
| 71 | FCGR2B | Fc fragment of IgG receptor IIb [Source:HGNC Symbol;Acc:HGNC:3618] | 5919 | 0.097 | 0.8295 | No |
| 72 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 6162 | 0.070 | 0.8234 | No |
| 73 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6776 | 0.000 | 0.8068 | No |
| 74 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9175 | 0.000 | 0.7420 | No |
| 75 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 9607 | 0.000 | 0.7304 | No |
| 76 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11736 | 0.000 | 0.6728 | No |
| 77 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 12854 | 0.000 | 0.6427 | No |
| 78 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13650 | 0.000 | 0.6212 | No |
| 79 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26791 | 0.000 | 0.2661 | No |
| 80 | KPNA3 | karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396] | 28214 | -0.096 | 0.2282 | No |
| 81 | PRKCD | protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399] | 29532 | -0.257 | 0.1940 | No |
| 82 | MAPKAPK2 | MAPK activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887] | 29640 | -0.271 | 0.1926 | No |
| 83 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 29770 | -0.284 | 0.1907 | No |
| 84 | PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase type 1 beta [Source:HGNC Symbol;Acc:HGNC:8995] | 30170 | -0.333 | 0.1817 | No |
| 85 | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987] | 33430 | -0.956 | 0.0989 | No |
