Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | REACTOME_DEFENSINS |
| Enrichment Score (ES) | 0.87719244 |
| Normalized Enrichment Score (NES) | 2.0302002 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 271 | 2.687 | 0.4336 | Yes |
| 2 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 776 | 1.649 | 0.6906 | Yes |
| 3 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 1290 | 1.222 | 0.8772 | Yes |
| 4 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7547 | 0.000 | 0.7083 | No |
| 5 | DEFB4B | defensin beta 4B [Source:HGNC Symbol;Acc:HGNC:30193] | 7548 | 0.000 | 0.7083 | No |
| 6 | ART1 | ADP-ribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:723] | 7816 | 0.000 | 0.7011 | No |
| 7 | DEFB129 | defensin beta 129 [Source:HGNC Symbol;Acc:HGNC:16218] | 7847 | 0.000 | 0.7003 | No |
| 8 | DEFB128 | defensin beta 128 [Source:HGNC Symbol;Acc:HGNC:18106] | 7848 | 0.000 | 0.7003 | No |
| 9 | DEFB127 | defensin beta 127 [Source:HGNC Symbol;Acc:HGNC:16206] | 7849 | 0.000 | 0.7003 | No |
| 10 | DEFB126 | defensin beta 126 [Source:HGNC Symbol;Acc:HGNC:15900] | 7850 | 0.000 | 0.7003 | No |
| 11 | DEFB125 | defensin beta 125 [Source:HGNC Symbol;Acc:HGNC:18105] | 7851 | 0.000 | 0.7003 | No |
| 12 | DEFB123 | defensin beta 123 [Source:HGNC Symbol;Acc:HGNC:18103] | 7852 | 0.000 | 0.7003 | No |
| 13 | DEFB121 | defensin beta 121 [Source:HGNC Symbol;Acc:HGNC:18101] | 7854 | 0.000 | 0.7002 | No |
| 14 | DEFB136 | defensin beta 136 [Source:HGNC Symbol;Acc:HGNC:34433] | 7859 | 0.000 | 0.7001 | No |
| 15 | DEFB135 | defensin beta 135 [Source:HGNC Symbol;Acc:HGNC:32400] | 7860 | 0.000 | 0.7001 | No |
| 16 | DEFB134 | defensin beta 134 [Source:HGNC Symbol;Acc:HGNC:32399] | 7861 | 0.000 | 0.7001 | No |
| 17 | DEFB133 | defensin beta 133 [Source:HGNC Symbol;Acc:HGNC:31331] | 7862 | 0.000 | 0.7001 | No |
| 18 | DEFB132 | defensin beta 132 [Source:HGNC Symbol;Acc:HGNC:33806] | 7863 | 0.000 | 0.7001 | No |
| 19 | DEFB119 | defensin beta 119 [Source:HGNC Symbol;Acc:HGNC:18099] | 8050 | 0.000 | 0.6951 | No |
| 20 | DEFB118 | defensin beta 118 [Source:HGNC Symbol;Acc:HGNC:16196] | 8051 | 0.000 | 0.6951 | No |
| 21 | DEFB116 | defensin beta 116 [Source:HGNC Symbol;Acc:HGNC:18097] | 8054 | 0.000 | 0.6951 | No |
| 22 | DEFB115 | defensin beta 115 [Source:HGNC Symbol;Acc:HGNC:18096] | 8057 | 0.000 | 0.6950 | No |
| 23 | DEFB114 | defensin beta 114 [Source:HGNC Symbol;Acc:HGNC:18095] | 8059 | 0.000 | 0.6950 | No |
| 24 | DEFB113 | defensin beta 113 [Source:HGNC Symbol;Acc:HGNC:18094] | 8060 | 0.000 | 0.6950 | No |
| 25 | DEFB112 | defensin beta 112 [Source:HGNC Symbol;Acc:HGNC:18093] | 8061 | 0.000 | 0.6950 | No |
| 26 | DEFB110 | defensin beta 110 [Source:HGNC Symbol;Acc:HGNC:18091] | 8063 | 0.000 | 0.6950 | No |
| 27 | DEFA1B | defensin alpha 1B [Source:HGNC Symbol;Acc:HGNC:33596] | 9108 | 0.000 | 0.6668 | No |
| 28 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15869 | 0.000 | 0.4843 | No |
| 29 | DEFB130A | defensin beta 130A [Source:HGNC Symbol;Acc:HGNC:18107] | 22017 | 0.000 | 0.3183 | No |
| 30 | DEFB130B | defensin beta 130B [Source:HGNC Symbol;Acc:HGNC:39814] | 22019 | 0.000 | 0.3183 | No |
| 31 | DEFB131A | defensin beta 131A [Source:HGNC Symbol;Acc:HGNC:18108] | 22020 | 0.000 | 0.3183 | No |
| 32 | DEFB103A | defensin beta 103A [Source:HGNC Symbol;Acc:HGNC:15967] | 22968 | 0.000 | 0.2927 | No |
| 33 | DEFB103B | defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702] | 22970 | 0.000 | 0.2927 | No |
| 34 | DEFB104B | defensin beta 104B [Source:HGNC Symbol;Acc:HGNC:26165] | 22987 | 0.000 | 0.2923 | No |
| 35 | DEFB104A | defensin beta 104A [Source:HGNC Symbol;Acc:HGNC:18115] | 22989 | 0.000 | 0.2922 | No |
| 36 | DEFB105A | defensin beta 105A [Source:HGNC Symbol;Acc:HGNC:18087] | 23000 | 0.000 | 0.2920 | No |
| 37 | DEFB105B | defensin beta 105B [Source:HGNC Symbol;Acc:HGNC:29930] | 23001 | 0.000 | 0.2920 | No |
| 38 | CCR6 | C-C motif chemokine receptor 6 [Source:HGNC Symbol;Acc:HGNC:1607] | 23015 | 0.000 | 0.2916 | No |
| 39 | DEFB106B | defensin beta 106B [Source:HGNC Symbol;Acc:HGNC:28879] | 23024 | 0.000 | 0.2914 | No |
| 40 | DEFB106A | defensin beta 106A [Source:HGNC Symbol;Acc:HGNC:18088] | 23030 | 0.000 | 0.2913 | No |
| 41 | DEFB107A | defensin beta 107A [Source:HGNC Symbol;Acc:HGNC:18086] | 23050 | 0.000 | 0.2907 | No |
| 42 | DEFB107B | defensin beta 107B [Source:HGNC Symbol;Acc:HGNC:31918] | 23052 | 0.000 | 0.2907 | No |
| 43 | DEFB108B | defensin beta 108B [Source:HGNC Symbol;Acc:HGNC:29966] | 23080 | 0.000 | 0.2900 | No |
| 44 | DEFB1 | defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766] | 23490 | 0.000 | 0.2789 | No |
| 45 | DEFA6 | defensin alpha 6 [Source:HGNC Symbol;Acc:HGNC:2765] | 23540 | 0.000 | 0.2776 | No |
| 46 | DEFA4 | defensin alpha 4 [Source:HGNC Symbol;Acc:HGNC:2763] | 23545 | 0.000 | 0.2775 | No |
| 47 | DEFA5 | defensin alpha 5 [Source:HGNC Symbol;Acc:HGNC:2764] | 23547 | 0.000 | 0.2775 | No |
| 48 | DEFA3 | defensin alpha 3 [Source:HGNC Symbol;Acc:HGNC:2762] | 23550 | 0.000 | 0.2774 | No |
| 49 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23552 | 0.000 | 0.2774 | No |
| 50 | PRSS3 | serine protease 3 [Source:HGNC Symbol;Acc:HGNC:9486] | 25363 | 0.000 | 0.2285 | No |
| 51 | DEFB124 | defensin beta 124 [Source:HGNC Symbol;Acc:HGNC:18104] | 31530 | -0.536 | 0.1501 | No |
