Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.89188546 |
| Normalized Enrichment Score (NES) | 2.0314658 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.925 | 0.0684 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 1 | 4.920 | 0.1368 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 2 | 4.920 | 0.2052 | Yes |
| 4 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 3 | 4.907 | 0.2733 | Yes |
| 5 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.875 | 0.3411 | Yes |
| 6 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 5 | 4.859 | 0.4086 | Yes |
| 7 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 16 | 4.731 | 0.4740 | Yes |
| 8 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 24 | 4.568 | 0.5373 | Yes |
| 9 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 40 | 4.264 | 0.5962 | Yes |
| 10 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 83 | 3.740 | 0.6470 | Yes |
| 11 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 172 | 3.156 | 0.6885 | Yes |
| 12 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 177 | 3.142 | 0.7320 | Yes |
| 13 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 338 | 2.498 | 0.7624 | Yes |
| 14 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 378 | 2.414 | 0.7949 | Yes |
| 15 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 591 | 1.934 | 0.8160 | Yes |
| 16 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 1086 | 1.374 | 0.8218 | Yes |
| 17 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1257 | 1.250 | 0.8346 | Yes |
| 18 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 1290 | 1.222 | 0.8507 | Yes |
| 19 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1349 | 1.178 | 0.8655 | Yes |
| 20 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 1404 | 1.146 | 0.8800 | Yes |
| 21 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 1571 | 1.078 | 0.8905 | Yes |
| 22 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 1985 | 0.905 | 0.8919 | Yes |
| 23 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 2674 | 0.669 | 0.8826 | No |
| 24 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 2947 | 0.602 | 0.8836 | No |
| 25 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 3511 | 0.478 | 0.8751 | No |
| 26 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 3981 | 0.393 | 0.8679 | No |
| 27 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4960 | 0.237 | 0.8448 | No |
| 28 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6766 | 0.000 | 0.7960 | No |
| 29 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6777 | 0.000 | 0.7958 | No |
| 30 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6780 | 0.000 | 0.7957 | No |
| 31 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13989 | 0.000 | 0.6011 | No |
| 32 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14918 | 0.000 | 0.5761 | No |
| 33 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14919 | 0.000 | 0.5761 | No |
| 34 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 16004 | 0.000 | 0.5468 | No |
| 35 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 16005 | 0.000 | 0.5468 | No |
| 36 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18269 | 0.000 | 0.4857 | No |
| 37 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19429 | 0.000 | 0.4545 | No |
| 38 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19438 | 0.000 | 0.4542 | No |
| 39 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22927 | 0.000 | 0.3601 | No |
| 40 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 23097 | 0.000 | 0.3555 | No |
| 41 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 24528 | 0.000 | 0.3169 | No |
| 42 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 26061 | 0.000 | 0.2756 | No |
| 43 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 26968 | 0.000 | 0.2511 | No |
| 44 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 27544 | -0.012 | 0.2358 | No |
| 45 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 30959 | -0.447 | 0.1498 | No |
| 46 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 34041 | -1.128 | 0.0823 | No |
