Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | SANA_TNF_SIGNALING_UP |
| Enrichment Score (ES) | 0.78786856 |
| Normalized Enrichment Score (NES) | 1.969468 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.7942153E-4 |
| FWER p-Value | 0.002 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 21 | 4.639 | 0.0455 | Yes |
| 2 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 29 | 4.507 | 0.0901 | Yes |
| 3 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 101 | 3.606 | 0.1240 | Yes |
| 4 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 104 | 3.593 | 0.1597 | Yes |
| 5 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 107 | 3.570 | 0.1951 | Yes |
| 6 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 111 | 3.533 | 0.2301 | Yes |
| 7 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 126 | 3.418 | 0.2637 | Yes |
| 8 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 133 | 3.364 | 0.2970 | Yes |
| 9 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 143 | 3.299 | 0.3295 | Yes |
| 10 | SERPINE1 | serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583] | 149 | 3.274 | 0.3619 | Yes |
| 11 | LIPG | lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623] | 199 | 3.040 | 0.3908 | Yes |
| 12 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 231 | 2.880 | 0.4185 | Yes |
| 13 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 236 | 2.845 | 0.4467 | Yes |
| 14 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 241 | 2.828 | 0.4747 | Yes |
| 15 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 246 | 2.791 | 0.5023 | Yes |
| 16 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 264 | 2.714 | 0.5288 | Yes |
| 17 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 288 | 2.633 | 0.5543 | Yes |
| 18 | PLA1A | phospholipase A1 member A [Source:HGNC Symbol;Acc:HGNC:17661] | 314 | 2.561 | 0.5791 | Yes |
| 19 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 317 | 2.547 | 0.6044 | Yes |
| 20 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 414 | 2.311 | 0.6247 | Yes |
| 21 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 491 | 2.110 | 0.6436 | Yes |
| 22 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 533 | 2.033 | 0.6627 | Yes |
| 23 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 551 | 2.002 | 0.6822 | Yes |
| 24 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 557 | 1.990 | 0.7018 | Yes |
| 25 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 720 | 1.721 | 0.7145 | Yes |
| 26 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 776 | 1.649 | 0.7294 | Yes |
| 27 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 1086 | 1.374 | 0.7347 | Yes |
| 28 | DNAJA1 | DnaJ heat shock protein family (Hsp40) member A1 [Source:HGNC Symbol;Acc:HGNC:5229] | 1217 | 1.275 | 0.7439 | Yes |
| 29 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 1404 | 1.146 | 0.7502 | Yes |
| 30 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 1446 | 1.128 | 0.7603 | Yes |
| 31 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1493 | 1.107 | 0.7701 | Yes |
| 32 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 1571 | 1.078 | 0.7787 | Yes |
| 33 | FTH1 | ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976] | 1622 | 1.056 | 0.7879 | Yes |
| 34 | RABL3 | RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072] | 2064 | 0.873 | 0.7846 | No |
| 35 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925] | 2494 | 0.726 | 0.7802 | No |
| 36 | HLA-B | major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932] | 2797 | 0.639 | 0.7784 | No |
| 37 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 2817 | 0.632 | 0.7842 | No |
| 38 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 2954 | 0.600 | 0.7865 | No |
| 39 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 3194 | 0.547 | 0.7855 | No |
| 40 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 3753 | 0.433 | 0.7747 | No |
| 41 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 4525 | 0.304 | 0.7569 | No |
| 42 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 5307 | 0.185 | 0.7376 | No |
| 43 | HLA-E | major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962] | 5753 | 0.122 | 0.7268 | No |
| 44 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 5838 | 0.108 | 0.7256 | No |
| 45 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 5898 | 0.100 | 0.7250 | No |
| 46 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 6174 | 0.068 | 0.7182 | No |
| 47 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 6273 | 0.055 | 0.7161 | No |
| 48 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6747 | 0.000 | 0.7033 | No |
| 49 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6780 | 0.000 | 0.7025 | No |
| 50 | PDGFRL | platelet derived growth factor receptor like [Source:HGNC Symbol;Acc:HGNC:8805] | 7883 | 0.000 | 0.6727 | No |
| 51 | APOL1 | apolipoprotein L1 [Source:HGNC Symbol;Acc:HGNC:618] | 10376 | 0.000 | 0.6054 | No |
| 52 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10378 | 0.000 | 0.6053 | No |
| 53 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 11022 | 0.000 | 0.5880 | No |
| 54 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11363 | 0.000 | 0.5788 | No |
| 55 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11470 | 0.000 | 0.5759 | No |
| 56 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12704 | 0.000 | 0.5426 | No |
| 57 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 13024 | 0.000 | 0.5340 | No |
| 58 | IL32 | interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] | 14024 | 0.000 | 0.5070 | No |
| 59 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 14076 | 0.000 | 0.5056 | No |
| 60 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18269 | 0.000 | 0.3923 | No |
| 61 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18909 | 0.000 | 0.3751 | No |
| 62 | CTHRC1 | collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831] | 18934 | 0.000 | 0.3744 | No |
| 63 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 19091 | 0.000 | 0.3702 | No |
| 64 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19425 | 0.000 | 0.3612 | No |
| 65 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19429 | 0.000 | 0.3611 | No |
| 66 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22918 | 0.000 | 0.2669 | No |
| 67 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22920 | 0.000 | 0.2668 | No |
| 68 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22927 | 0.000 | 0.2667 | No |
| 69 | ANO9 | anoctamin 9 [Source:HGNC Symbol;Acc:HGNC:20679] | 25075 | 0.000 | 0.2087 | No |
| 70 | SSPN | sarcospan [Source:HGNC Symbol;Acc:HGNC:11322] | 27098 | 0.000 | 0.1540 | No |
| 71 | DRAM1 | DNA damage regulated autophagy modulator 1 [Source:HGNC Symbol;Acc:HGNC:25645] | 27648 | -0.027 | 0.1395 | No |
| 72 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 27760 | -0.040 | 0.1369 | No |
| 73 | ATP13A3 | ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113] | 28705 | -0.151 | 0.1129 | No |
| 74 | RAC3 | Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803] | 28955 | -0.186 | 0.1080 | No |
| 75 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 30184 | -0.335 | 0.0781 | No |
| 76 | SPAG9 | sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524] | 30446 | -0.371 | 0.0748 | No |
| 77 | C1QTNF1 | C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324] | 31409 | -0.514 | 0.0539 | No |
| 78 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 32512 | -0.724 | 0.0313 | No |
| 79 | NCEH1 | neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260] | 34630 | -1.341 | -0.0126 | No |
| 80 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 35161 | -1.604 | -0.0110 | No |
| 81 | BPGM | bisphosphoglycerate mutase [Source:HGNC Symbol;Acc:HGNC:1093] | 35273 | -1.662 | 0.0025 | No |
| 82 | OXR1 | oxidation resistance 1 [Source:HGNC Symbol;Acc:HGNC:15822] | 35991 | -2.146 | 0.0045 | No |
| 83 | SMAD3 | SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769] | 36388 | -2.534 | 0.0190 | No |
