Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.8103062 |
| Normalized Enrichment Score (NES) | 1.9880165 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 12 | 4.785 | 0.0357 | Yes |
| 2 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 20 | 4.680 | 0.0708 | Yes |
| 3 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 22 | 4.617 | 0.1056 | Yes |
| 4 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 23 | 4.586 | 0.1401 | Yes |
| 5 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 29 | 4.507 | 0.1739 | Yes |
| 6 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 32 | 4.445 | 0.2074 | Yes |
| 7 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 50 | 4.094 | 0.2378 | Yes |
| 8 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 64 | 3.980 | 0.2674 | Yes |
| 9 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 96 | 3.630 | 0.2939 | Yes |
| 10 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 104 | 3.593 | 0.3208 | Yes |
| 11 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 107 | 3.570 | 0.3476 | Yes |
| 12 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 142 | 3.303 | 0.3716 | Yes |
| 13 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 148 | 3.287 | 0.3962 | Yes |
| 14 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 150 | 3.268 | 0.4208 | Yes |
| 15 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 156 | 3.244 | 0.4451 | Yes |
| 16 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 177 | 3.142 | 0.4683 | Yes |
| 17 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 183 | 3.113 | 0.4916 | Yes |
| 18 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 220 | 2.934 | 0.5127 | Yes |
| 19 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 223 | 2.927 | 0.5347 | Yes |
| 20 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 231 | 2.880 | 0.5562 | Yes |
| 21 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 241 | 2.828 | 0.5773 | Yes |
| 22 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 259 | 2.733 | 0.5974 | Yes |
| 23 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 265 | 2.713 | 0.6177 | Yes |
| 24 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 274 | 2.682 | 0.6377 | Yes |
| 25 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 305 | 2.585 | 0.6564 | Yes |
| 26 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 356 | 2.464 | 0.6736 | Yes |
| 27 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 417 | 2.306 | 0.6894 | Yes |
| 28 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 454 | 2.211 | 0.7050 | Yes |
| 29 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 491 | 2.110 | 0.7200 | Yes |
| 30 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 494 | 2.104 | 0.7358 | Yes |
| 31 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 621 | 1.888 | 0.7466 | Yes |
| 32 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 720 | 1.721 | 0.7569 | Yes |
| 33 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 776 | 1.649 | 0.7678 | Yes |
| 34 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 785 | 1.642 | 0.7800 | Yes |
| 35 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 966 | 1.461 | 0.7861 | Yes |
| 36 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 1028 | 1.414 | 0.7951 | Yes |
| 37 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 1287 | 1.223 | 0.7974 | Yes |
| 38 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 1404 | 1.146 | 0.8029 | Yes |
| 39 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 1571 | 1.078 | 0.8065 | Yes |
| 40 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 1723 | 1.015 | 0.8101 | Yes |
| 41 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1993 | 0.902 | 0.8096 | Yes |
| 42 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 2197 | 0.820 | 0.8103 | Yes |
| 43 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 3000 | 0.590 | 0.7931 | No |
| 44 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 3511 | 0.478 | 0.7829 | No |
| 45 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 4273 | 0.344 | 0.7649 | No |
| 46 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 4525 | 0.304 | 0.7604 | No |
| 47 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 4964 | 0.237 | 0.7504 | No |
| 48 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 5324 | 0.182 | 0.7421 | No |
| 49 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 6174 | 0.068 | 0.7196 | No |
| 50 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 7520 | 0.000 | 0.6833 | No |
| 51 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8939 | 0.000 | 0.6450 | No |
| 52 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 9070 | 0.000 | 0.6415 | No |
| 53 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10629 | 0.000 | 0.5994 | No |
| 54 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11470 | 0.000 | 0.5767 | No |
| 55 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11761 | 0.000 | 0.5688 | No |
| 56 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 14076 | 0.000 | 0.5063 | No |
| 57 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 18049 | 0.000 | 0.3990 | No |
| 58 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18269 | 0.000 | 0.3931 | No |
| 59 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18875 | 0.000 | 0.3768 | No |
| 60 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18989 | 0.000 | 0.3737 | No |
| 61 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19425 | 0.000 | 0.3619 | No |
| 62 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19438 | 0.000 | 0.3616 | No |
| 63 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 19823 | 0.000 | 0.3512 | No |
| 64 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 20005 | 0.000 | 0.3464 | No |
| 65 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 22120 | 0.000 | 0.2892 | No |
| 66 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 22152 | 0.000 | 0.2884 | No |
| 67 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22920 | 0.000 | 0.2677 | No |
| 68 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22927 | 0.000 | 0.2675 | No |
| 69 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26791 | 0.000 | 0.1632 | No |
| 70 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 30182 | -0.334 | 0.0741 | No |
| 71 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 31181 | -0.480 | 0.0507 | No |
| 72 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 32690 | -0.765 | 0.0158 | No |
| 73 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 32837 | -0.801 | 0.0178 | No |
| 74 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 34725 | -1.387 | -0.0227 | No |
| 75 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 36259 | -2.394 | -0.0461 | No |
| 76 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 36487 | -2.659 | -0.0322 | No |
| 77 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 36709 | -3.005 | -0.0155 | No |
| 78 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 36888 | -3.420 | 0.0055 | No |
