Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GGGNNTTTCC_NFKB_Q6_01 |
| Enrichment Score (ES) | 0.49721125 |
| Normalized Enrichment Score (NES) | 1.3061994 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 1 | 4.920 | 0.0356 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.875 | 0.0709 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 24 | 4.568 | 0.1035 | Yes |
| 4 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 36 | 4.325 | 0.1346 | Yes |
| 5 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 43 | 4.212 | 0.1650 | Yes |
| 6 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 104 | 3.593 | 0.1894 | Yes |
| 7 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 107 | 3.570 | 0.2152 | Yes |
| 8 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 142 | 3.303 | 0.2382 | Yes |
| 9 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 195 | 3.069 | 0.2591 | Yes |
| 10 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 341 | 2.489 | 0.2732 | Yes |
| 11 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 417 | 2.306 | 0.2879 | Yes |
| 12 | SH2B3 | SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605] | 446 | 2.233 | 0.3033 | Yes |
| 13 | FHL3 | four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704] | 456 | 2.207 | 0.3191 | Yes |
| 14 | RYBP | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | 539 | 2.026 | 0.3315 | Yes |
| 15 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 639 | 1.855 | 0.3423 | Yes |
| 16 | RAP2C | RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165] | 670 | 1.800 | 0.3545 | Yes |
| 17 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 686 | 1.780 | 0.3670 | Yes |
| 18 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 864 | 1.555 | 0.3735 | Yes |
| 19 | ORAI1 | ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] | 870 | 1.549 | 0.3846 | Yes |
| 20 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 893 | 1.532 | 0.3951 | Yes |
| 21 | BATF | basic leucine zipper ATF-like transcription factor [Source:HGNC Symbol;Acc:HGNC:958] | 1165 | 1.314 | 0.3973 | Yes |
| 22 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1257 | 1.250 | 0.4039 | Yes |
| 23 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 1294 | 1.218 | 0.4118 | Yes |
| 24 | CCDC80 | coiled-coil domain containing 80 [Source:HGNC Symbol;Acc:HGNC:30649] | 1346 | 1.179 | 0.4189 | Yes |
| 25 | ZFAND3 | zinc finger AN1-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18019] | 1347 | 1.179 | 0.4275 | Yes |
| 26 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 1452 | 1.125 | 0.4328 | Yes |
| 27 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1556 | 1.085 | 0.4379 | Yes |
| 28 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 1618 | 1.058 | 0.4439 | Yes |
| 29 | CPEB4 | cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747] | 1662 | 1.043 | 0.4503 | Yes |
| 30 | TPM3 | tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012] | 1695 | 1.024 | 0.4569 | Yes |
| 31 | IER5 | immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393] | 1700 | 1.023 | 0.4642 | Yes |
| 32 | UBE2M | ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491] | 1851 | 0.965 | 0.4671 | Yes |
| 33 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 1909 | 0.940 | 0.4724 | Yes |
| 34 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 1983 | 0.906 | 0.4770 | Yes |
| 35 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 1994 | 0.902 | 0.4833 | Yes |
| 36 | GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804] | 2096 | 0.858 | 0.4868 | Yes |
| 37 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 2261 | 0.798 | 0.4881 | Yes |
| 38 | N4BP1 | NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850] | 2450 | 0.737 | 0.4884 | Yes |
| 39 | G3BP1 | G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292] | 2489 | 0.728 | 0.4926 | Yes |
| 40 | KY | kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576] | 2644 | 0.681 | 0.4934 | Yes |
| 41 | WNT10A | Wnt family member 10A [Source:HGNC Symbol;Acc:HGNC:13829] | 2733 | 0.654 | 0.4957 | Yes |
| 42 | CXCR5 | C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060] | 2847 | 0.625 | 0.4972 | Yes |
| 43 | RBMS1 | RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907] | 3775 | 0.429 | 0.4752 | No |
| 44 | UPF2 | UPF2 regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854] | 4550 | 0.301 | 0.4565 | No |
| 45 | BMP2K | BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041] | 4745 | 0.273 | 0.4532 | No |
| 46 | RSPRY1 | ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420] | 4866 | 0.252 | 0.4518 | No |
| 47 | SLAMF8 | SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391] | 4957 | 0.238 | 0.4511 | No |
| 48 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4960 | 0.237 | 0.4527 | No |
| 49 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 5062 | 0.221 | 0.4516 | No |
| 50 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 5352 | 0.177 | 0.4451 | No |
| 51 | FOXS1 | forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735] | 5605 | 0.140 | 0.4393 | No |
| 52 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 5614 | 0.139 | 0.4401 | No |
| 53 | WRAP53 | WD repeat containing antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522] | 5895 | 0.100 | 0.4332 | No |
| 54 | SMPD3 | sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240] | 6143 | 0.072 | 0.4271 | No |
| 55 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 6174 | 0.068 | 0.4267 | No |
| 56 | TCEA2 | transcription elongation factor A2 [Source:HGNC Symbol;Acc:HGNC:11614] | 6609 | 0.013 | 0.4151 | No |
| 57 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8573 | 0.000 | 0.3620 | No |
| 58 | POU2F3 | POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:19864] | 8760 | 0.000 | 0.3569 | No |
| 59 | PRR34 | PRR34 long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:25606] | 9179 | 0.000 | 0.3456 | No |
| 60 | MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765] | 9432 | 0.000 | 0.3388 | No |
| 61 | TNFRSF9 | TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] | 10108 | 0.000 | 0.3205 | No |
| 62 | KCNS3 | potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] | 10218 | 0.000 | 0.3176 | No |
| 63 | IL1RAPL1 | interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996] | 10697 | 0.000 | 0.3047 | No |
| 64 | NRIP2 | nuclear receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23078] | 11102 | 0.000 | 0.2937 | No |
| 65 | NTRK3 | neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033] | 11220 | 0.000 | 0.2906 | No |
| 66 | CNTF | ciliary neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:2169] | 12583 | 0.000 | 0.2537 | No |
| 67 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12742 | 0.000 | 0.2494 | No |
| 68 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 13024 | 0.000 | 0.2418 | No |
| 69 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13736 | 0.000 | 0.2226 | No |
| 70 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14501 | 0.000 | 0.2019 | No |
| 71 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16357 | 0.000 | 0.1517 | No |
| 72 | IL2 | interleukin 2 [Source:HGNC Symbol;Acc:HGNC:6001] | 17749 | 0.000 | 0.1141 | No |
| 73 | LPO | lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] | 18681 | 0.000 | 0.0889 | No |
| 74 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19041 | 0.000 | 0.0792 | No |
| 75 | BNC2 | basonuclin 2 [Source:HGNC Symbol;Acc:HGNC:30988] | 19251 | 0.000 | 0.0735 | No |
| 76 | NR2F2 | nuclear receptor subfamily 2 group F member 2 [Source:HGNC Symbol;Acc:HGNC:7976] | 19540 | 0.000 | 0.0657 | No |
| 77 | ZNF532 | zinc finger protein 532 [Source:HGNC Symbol;Acc:HGNC:30940] | 21842 | 0.000 | 0.0035 | No |
| 78 | CD70 | CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937] | 23075 | 0.000 | -0.0299 | No |
| 79 | C1QL1 | complement C1q like 1 [Source:HGNC Symbol;Acc:HGNC:24182] | 23270 | 0.000 | -0.0351 | No |
| 80 | ENTHD1 | ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352] | 23428 | 0.000 | -0.0394 | No |
| 81 | LAMA1 | laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481] | 23755 | 0.000 | -0.0482 | No |
| 82 | NRGN | neurogranin [Source:HGNC Symbol;Acc:HGNC:8000] | 24176 | 0.000 | -0.0595 | No |
| 83 | FTHL17 | ferritin heavy chain like 17 [Source:HGNC Symbol;Acc:HGNC:3987] | 24426 | 0.000 | -0.0663 | No |
| 84 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 25417 | 0.000 | -0.0931 | No |
| 85 | SOX5 | SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201] | 26148 | 0.000 | -0.1128 | No |
| 86 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 27645 | -0.027 | -0.1531 | No |
| 87 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon [Source:HGNC Symbol;Acc:HGNC:9313] | 27736 | -0.037 | -0.1553 | No |
| 88 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 28018 | -0.069 | -0.1624 | No |
| 89 | SP6 | Sp6 transcription factor [Source:HGNC Symbol;Acc:HGNC:14530] | 28201 | -0.094 | -0.1666 | No |
| 90 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 28281 | -0.105 | -0.1680 | No |
| 91 | RASSF2 | Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883] | 28474 | -0.127 | -0.1723 | No |
| 92 | DCLK1 | doublecortin like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2700] | 28563 | -0.135 | -0.1737 | No |
| 93 | SLC25A18 | solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988] | 29389 | -0.237 | -0.1943 | No |
| 94 | PLXNB1 | plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103] | 29552 | -0.259 | -0.1968 | No |
| 95 | ARID1A | AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110] | 29587 | -0.264 | -0.1958 | No |
| 96 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 29665 | -0.274 | -0.1959 | No |
| 97 | CDC27 | cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728] | 29928 | -0.302 | -0.2008 | No |
| 98 | TNKS1BP1 | tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081] | 30236 | -0.341 | -0.2066 | No |
| 99 | PSME3IP1 | proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856] | 30339 | -0.355 | -0.2068 | No |
| 100 | ENO3 | enolase 3 [Source:HGNC Symbol;Acc:HGNC:3354] | 31523 | -0.535 | -0.2349 | No |
| 101 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 31703 | -0.564 | -0.2357 | No |
| 102 | CREB1 | cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345] | 31913 | -0.595 | -0.2370 | No |
| 103 | MIDEAS | mitotic deacetylase associated SANT domain protein [Source:HGNC Symbol;Acc:HGNC:19853] | 32016 | -0.617 | -0.2353 | No |
| 104 | FUT7 | fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018] | 32117 | -0.635 | -0.2334 | No |
| 105 | UBE2H | ubiquitin conjugating enzyme E2 H [Source:HGNC Symbol;Acc:HGNC:12484] | 32477 | -0.717 | -0.2379 | No |
| 106 | HOXA4 | homeobox A4 [Source:HGNC Symbol;Acc:HGNC:5105] | 33658 | -1.021 | -0.2625 | No |
| 107 | RPS6KA4 | ribosomal protein S6 kinase A4 [Source:HGNC Symbol;Acc:HGNC:10433] | 33779 | -1.048 | -0.2581 | No |
| 108 | CCDC107 | coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465] | 33789 | -1.051 | -0.2507 | No |
| 109 | GEM | GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] | 33949 | -1.096 | -0.2471 | No |
| 110 | PKN1 | protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405] | 34013 | -1.119 | -0.2407 | No |
| 111 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 34055 | -1.132 | -0.2336 | No |
| 112 | CHD6 | chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057] | 34166 | -1.166 | -0.2281 | No |
| 113 | ALG6 | ALG6 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157] | 34199 | -1.178 | -0.2204 | No |
| 114 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 34253 | -1.199 | -0.2132 | No |
| 115 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 34306 | -1.219 | -0.2058 | No |
| 116 | CNTNAP1 | contactin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:8011] | 34520 | -1.302 | -0.2021 | No |
| 117 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 34633 | -1.342 | -0.1954 | No |
| 118 | STX4 | syntaxin 4 [Source:HGNC Symbol;Acc:HGNC:11439] | 34709 | -1.380 | -0.1874 | No |
| 119 | JAK3 | Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193] | 35027 | -1.533 | -0.1849 | No |
| 120 | PNKD | PNKD metallo-beta-lactamase domain containing [Source:HGNC Symbol;Acc:HGNC:9153] | 35058 | -1.550 | -0.1745 | No |
| 121 | KAT7 | lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016] | 35071 | -1.557 | -0.1635 | No |
| 122 | SLC44A1 | solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798] | 35189 | -1.619 | -0.1549 | No |
| 123 | SH3KBP1 | SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867] | 35260 | -1.656 | -0.1448 | No |
| 124 | CYLD | CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584] | 35378 | -1.719 | -0.1355 | No |
| 125 | SLC6A12 | solute carrier family 6 member 12 [Source:HGNC Symbol;Acc:HGNC:11045] | 35440 | -1.756 | -0.1244 | No |
| 126 | HIVEP1 | HIVEP zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4920] | 35734 | -1.948 | -0.1182 | No |
| 127 | TRIM47 | tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020] | 35849 | -2.042 | -0.1065 | No |
| 128 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 36203 | -2.331 | -0.0992 | No |
| 129 | TOM1L1 | target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983] | 36335 | -2.464 | -0.0849 | No |
| 130 | LIX1L | limb and CNS expressed 1 like [Source:HGNC Symbol;Acc:HGNC:28715] | 36375 | -2.508 | -0.0677 | No |
| 131 | CALCOCO1 | calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306] | 36422 | -2.575 | -0.0503 | No |
| 132 | S1PR2 | sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169] | 36565 | -2.775 | -0.0340 | No |
| 133 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36638 | -2.886 | -0.0151 | No |
| 134 | FAM117A | family with sequence similarity 117 member A [Source:HGNC Symbol;Acc:HGNC:24179] | 36976 | -3.760 | 0.0031 | No |
