Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | MIR4290 |
| Enrichment Score (ES) | 0.59604424 |
| Normalized Enrichment Score (NES) | 1.443632 |
| Nominal p-value | 0.010256411 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.997 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MAP1B | microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] | 65 | 3.959 | 0.0788 | Yes |
| 2 | TRIB1 | tribbles pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:16891] | 68 | 3.896 | 0.1580 | Yes |
| 3 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 153 | 3.258 | 0.2220 | Yes |
| 4 | PTPN5 | protein tyrosine phosphatase non-receptor type 5 [Source:HGNC Symbol;Acc:HGNC:9657] | 205 | 3.022 | 0.2822 | Yes |
| 5 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 378 | 2.414 | 0.3266 | Yes |
| 6 | SESN2 | sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] | 693 | 1.772 | 0.3542 | Yes |
| 7 | ANKRD52 | ankyrin repeat domain 52 [Source:HGNC Symbol;Acc:HGNC:26614] | 916 | 1.508 | 0.3789 | Yes |
| 8 | CLCF1 | cardiotrophin like cytokine factor 1 [Source:HGNC Symbol;Acc:HGNC:17412] | 1025 | 1.415 | 0.4048 | Yes |
| 9 | MAT2A | methionine adenosyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:6904] | 1124 | 1.344 | 0.4295 | Yes |
| 10 | MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1 like [Source:HGNC Symbol;Acc:HGNC:19840] | 1168 | 1.313 | 0.4551 | Yes |
| 11 | TSPAN5 | tetraspanin 5 [Source:HGNC Symbol;Acc:HGNC:17753] | 1170 | 1.310 | 0.4817 | Yes |
| 12 | WIPF2 | WAS/WASL interacting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:30923] | 1419 | 1.141 | 0.4982 | Yes |
| 13 | MTAP | methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413] | 1790 | 0.991 | 0.5084 | Yes |
| 14 | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:682] | 1897 | 0.945 | 0.5247 | Yes |
| 15 | SMG5 | SMG5 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:24644] | 1959 | 0.914 | 0.5417 | Yes |
| 16 | PPP1R9B | protein phosphatase 1 regulatory subunit 9B [Source:HGNC Symbol;Acc:HGNC:9298] | 1989 | 0.904 | 0.5593 | Yes |
| 17 | ERLIN2 | ER lipid raft associated 2 [Source:HGNC Symbol;Acc:HGNC:1356] | 2161 | 0.832 | 0.5716 | Yes |
| 18 | ZNF276 | zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330] | 2295 | 0.788 | 0.5841 | Yes |
| 19 | NRBP1 | nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993] | 2415 | 0.747 | 0.5960 | Yes |
| 20 | NUP188 | nucleoporin 188 [Source:HGNC Symbol;Acc:HGNC:17859] | 3690 | 0.444 | 0.5707 | No |
| 21 | CAPZA1 | capping actin protein of muscle Z-line subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:1488] | 4317 | 0.336 | 0.5606 | No |
| 22 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 4780 | 0.266 | 0.5535 | No |
| 23 | KDM4A | lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978] | 5436 | 0.164 | 0.5392 | No |
| 24 | SNX8 | sorting nexin 8 [Source:HGNC Symbol;Acc:HGNC:14972] | 5545 | 0.148 | 0.5393 | No |
| 25 | RPEL1 | ribulose-5-phosphate-3-epimerase like 1 [Source:HGNC Symbol;Acc:HGNC:45241] | 6231 | 0.060 | 0.5220 | No |
| 26 | CCNT1 | cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599] | 6298 | 0.052 | 0.5213 | No |
| 27 | RPE | ribulose-5-phosphate-3-epimerase [Source:HGNC Symbol;Acc:HGNC:10293] | 6484 | 0.031 | 0.5169 | No |
| 28 | PRPH2 | peripherin 2 [Source:HGNC Symbol;Acc:HGNC:9942] | 8761 | 0.000 | 0.4554 | No |
| 29 | CASP14 | caspase 14 [Source:HGNC Symbol;Acc:HGNC:1502] | 9494 | 0.000 | 0.4357 | No |
| 30 | ZNF185 | zinc finger protein 185 with LIM domain [Source:HGNC Symbol;Acc:HGNC:12976] | 9940 | 0.000 | 0.4236 | No |
| 31 | AWAT1 | acyl-CoA wax alcohol acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23252] | 10136 | 0.000 | 0.4184 | No |
| 32 | ADAM11 | ADAM metallopeptidase domain 11 [Source:HGNC Symbol;Acc:HGNC:189] | 10232 | 0.000 | 0.4158 | No |
| 33 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10305 | 0.000 | 0.4139 | No |
| 34 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11789 | 0.000 | 0.3738 | No |
| 35 | LINC02881 | long intergenic non-protein coding RNA 2881 [Source:HGNC Symbol;Acc:HGNC:51236] | 13515 | 0.000 | 0.3272 | No |
| 36 | SORCS2 | sortilin related VPS10 domain containing receptor 2 [Source:HGNC Symbol;Acc:HGNC:16698] | 14856 | 0.000 | 0.2910 | No |
| 37 | RGS17 | regulator of G protein signaling 17 [Source:HGNC Symbol;Acc:HGNC:14088] | 16765 | 0.000 | 0.2395 | No |
| 38 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 17979 | 0.000 | 0.2067 | No |
| 39 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18910 | 0.000 | 0.1816 | No |
| 40 | KRT77 | keratin 77 [Source:HGNC Symbol;Acc:HGNC:20411] | 22010 | 0.000 | 0.0979 | No |
| 41 | CCDC9B | coiled-coil domain containing 9B [Source:HGNC Symbol;Acc:HGNC:33488] | 24285 | 0.000 | 0.0365 | No |
| 42 | FGF9 | fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687] | 25429 | 0.000 | 0.0056 | No |
| 43 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 26062 | 0.000 | -0.0115 | No |
| 44 | CSN1S1 | casein alpha s1 [Source:HGNC Symbol;Acc:HGNC:2445] | 26372 | 0.000 | -0.0198 | No |
| 45 | ELFN2 | extracellular leucine rich repeat and fibronectin type III domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29396] | 26422 | 0.000 | -0.0211 | No |
| 46 | NFASC | neurofascin [Source:HGNC Symbol;Acc:HGNC:29866] | 27321 | 0.000 | -0.0454 | No |
| 47 | TMEM192 | transmembrane protein 192 [Source:HGNC Symbol;Acc:HGNC:26775] | 27492 | -0.002 | -0.0499 | No |
| 48 | TM2D2 | TM2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24127] | 27652 | -0.028 | -0.0537 | No |
| 49 | AKIRIN2 | akirin 2 [Source:HGNC Symbol;Acc:HGNC:21407] | 27662 | -0.029 | -0.0533 | No |
| 50 | ZNF541 | zinc finger protein 541 [Source:HGNC Symbol;Acc:HGNC:25294] | 28584 | -0.138 | -0.0754 | No |
| 51 | TIMM23B | translocase of inner mitochondrial membrane 23 homolog B [Source:HGNC Symbol;Acc:HGNC:23581] | 28590 | -0.139 | -0.0727 | No |
| 52 | STK32C | serine/threonine kinase 32C [Source:HGNC Symbol;Acc:HGNC:21332] | 28724 | -0.153 | -0.0732 | No |
| 53 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 28799 | -0.163 | -0.0719 | No |
| 54 | ATP8A2 | ATPase phospholipid transporting 8A2 [Source:HGNC Symbol;Acc:HGNC:13533] | 28987 | -0.189 | -0.0731 | No |
| 55 | PYCR1 | pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:HGNC:9721] | 30384 | -0.362 | -0.1034 | No |
| 56 | TMEM265 | transmembrane protein 265 [Source:HGNC Symbol;Acc:HGNC:51241] | 30435 | -0.369 | -0.0973 | No |
| 57 | TNKS | tankyrase [Source:HGNC Symbol;Acc:HGNC:11941] | 30628 | -0.396 | -0.0944 | No |
| 58 | SART3 | spliceosome associated factor 3, U4/U6 recycling protein [Source:HGNC Symbol;Acc:HGNC:16860] | 30653 | -0.399 | -0.0869 | No |
| 59 | MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:6882] | 30695 | -0.406 | -0.0798 | No |
| 60 | ZFAND6 | zinc finger AN1-type containing 6 [Source:HGNC Symbol;Acc:HGNC:30164] | 31959 | -0.607 | -0.1016 | No |
| 61 | ENOX2 | ecto-NOX disulfide-thiol exchanger 2 [Source:HGNC Symbol;Acc:HGNC:2259] | 32081 | -0.629 | -0.0920 | No |
| 62 | SUN1 | Sad1 and UNC84 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18587] | 33843 | -1.066 | -0.1179 | No |
| 63 | ARHGEF17 | Rho guanine nucleotide exchange factor 17 [Source:HGNC Symbol;Acc:HGNC:21726] | 34163 | -1.165 | -0.1028 | No |
| 64 | GID4 | GID complex subunit 4 homolog [Source:HGNC Symbol;Acc:HGNC:28453] | 34460 | -1.277 | -0.0848 | No |
| 65 | DCTN4 | dynactin subunit 4 [Source:HGNC Symbol;Acc:HGNC:15518] | 34612 | -1.336 | -0.0617 | No |
| 66 | PRKDC | protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413] | 35043 | -1.541 | -0.0420 | No |
| 67 | CAMTA1 | calmodulin binding transcription activator 1 [Source:HGNC Symbol;Acc:HGNC:18806] | 35531 | -1.809 | -0.0183 | No |
| 68 | CTDSP2 | CTD small phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:17077] | 36686 | -2.970 | 0.0109 | No |
