Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | PR_02 |
| Enrichment Score (ES) | 0.4682293 |
| Normalized Enrichment Score (NES) | 1.2375286 |
| Nominal p-value | 0.048780486 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 34 | 4.388 | 0.0376 | Yes |
| 2 | CALCRL | calcitonin receptor like receptor [Source:HGNC Symbol;Acc:HGNC:16709] | 58 | 4.032 | 0.0724 | Yes |
| 3 | MAP1B | microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] | 65 | 3.959 | 0.1070 | Yes |
| 4 | ID3 | inhibitor of DNA binding 3, HLH protein [Source:HGNC Symbol;Acc:HGNC:5362] | 66 | 3.938 | 0.1416 | Yes |
| 5 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 105 | 3.585 | 0.1721 | Yes |
| 6 | SEMA4C | semaphorin 4C [Source:HGNC Symbol;Acc:HGNC:10731] | 132 | 3.365 | 0.2009 | Yes |
| 7 | SMOX | spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862] | 173 | 3.151 | 0.2275 | Yes |
| 8 | SKIL | SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897] | 200 | 3.039 | 0.2535 | Yes |
| 9 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 227 | 2.891 | 0.2782 | Yes |
| 10 | DST | dystonin [Source:HGNC Symbol;Acc:HGNC:1090] | 260 | 2.728 | 0.3013 | Yes |
| 11 | CD36 | CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663] | 374 | 2.425 | 0.3195 | Yes |
| 12 | PIGV | phosphatidylinositol glycan anchor biosynthesis class V [Source:HGNC Symbol;Acc:HGNC:26031] | 387 | 2.390 | 0.3402 | Yes |
| 13 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 416 | 2.309 | 0.3597 | Yes |
| 14 | DOCK4 | dedicator of cytokinesis 4 [Source:HGNC Symbol;Acc:HGNC:19192] | 439 | 2.251 | 0.3789 | Yes |
| 15 | PXN | paxillin [Source:HGNC Symbol;Acc:HGNC:9718] | 441 | 2.249 | 0.3986 | Yes |
| 16 | RGS3 | regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999] | 484 | 2.138 | 0.4163 | Yes |
| 17 | NCDN | neurochondrin [Source:HGNC Symbol;Acc:HGNC:17597] | 764 | 1.665 | 0.4234 | Yes |
| 18 | PHC2 | polyhomeotic homolog 2 [Source:HGNC Symbol;Acc:HGNC:3183] | 868 | 1.550 | 0.4342 | Yes |
| 19 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1162 | 1.317 | 0.4378 | Yes |
| 20 | SYNCRIP | synaptotagmin binding cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:HGNC:16918] | 1485 | 1.111 | 0.4389 | Yes |
| 21 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 1532 | 1.093 | 0.4472 | Yes |
| 22 | CPEB4 | cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747] | 1662 | 1.043 | 0.4529 | Yes |
| 23 | GRB2 | growth factor receptor bound protein 2 [Source:HGNC Symbol;Acc:HGNC:4566] | 2378 | 0.761 | 0.4402 | Yes |
| 24 | DUSP10 | dual specificity phosphatase 10 [Source:HGNC Symbol;Acc:HGNC:3065] | 2397 | 0.753 | 0.4464 | Yes |
| 25 | RBM3 | RNA binding motif protein 3 [Source:HGNC Symbol;Acc:HGNC:9900] | 2435 | 0.741 | 0.4519 | Yes |
| 26 | CCDC126 | coiled-coil domain containing 126 [Source:HGNC Symbol;Acc:HGNC:22398] | 2507 | 0.721 | 0.4563 | Yes |
| 27 | NLK | nemo like kinase [Source:HGNC Symbol;Acc:HGNC:29858] | 2566 | 0.703 | 0.4609 | Yes |
| 28 | XPNPEP3 | X-prolyl aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:28052] | 2629 | 0.686 | 0.4652 | Yes |
| 29 | OPN3 | opsin 3 [Source:HGNC Symbol;Acc:HGNC:14007] | 2783 | 0.642 | 0.4667 | Yes |
| 30 | LOX | lysyl oxidase [Source:HGNC Symbol;Acc:HGNC:6664] | 2961 | 0.599 | 0.4672 | Yes |
| 31 | CA5B | carbonic anhydrase 5B [Source:HGNC Symbol;Acc:HGNC:1378] | 3138 | 0.560 | 0.4674 | Yes |
| 32 | ACBD3 | acyl-CoA binding domain containing 3 [Source:HGNC Symbol;Acc:HGNC:15453] | 3278 | 0.527 | 0.4682 | Yes |
| 33 | FGF17 | fibroblast growth factor 17 [Source:HGNC Symbol;Acc:HGNC:3673] | 3492 | 0.483 | 0.4667 | No |
| 34 | RAB30 | RAB30, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9770] | 3747 | 0.433 | 0.4636 | No |
| 35 | LARP4 | La ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:24320] | 3864 | 0.413 | 0.4641 | No |
| 36 | DSTN | destrin, actin depolymerizing factor [Source:HGNC Symbol;Acc:HGNC:15750] | 4310 | 0.337 | 0.4550 | No |
| 37 | AKAP3 | A-kinase anchoring protein 3 [Source:HGNC Symbol;Acc:HGNC:373] | 4394 | 0.324 | 0.4556 | No |
| 38 | EPG5 | ectopic P-granules autophagy protein 5 homolog [Source:HGNC Symbol;Acc:HGNC:29331] | 4572 | 0.298 | 0.4535 | No |
| 39 | MPZ | myelin protein zero [Source:HGNC Symbol;Acc:HGNC:7225] | 4691 | 0.282 | 0.4528 | No |
| 40 | VCPKMT | valosin containing protein lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:20352] | 4702 | 0.280 | 0.4549 | No |
| 41 | KCNK10 | potassium two pore domain channel subfamily K member 10 [Source:HGNC Symbol;Acc:HGNC:6273] | 4875 | 0.251 | 0.4525 | No |
| 42 | DOLPP1 | dolichyldiphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:29565] | 5011 | 0.229 | 0.4508 | No |
| 43 | RAB1B | RAB1B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18370] | 5805 | 0.113 | 0.4304 | No |
| 44 | MYH4 | myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574] | 6172 | 0.068 | 0.4211 | No |
| 45 | TECTA | tectorin alpha [Source:HGNC Symbol;Acc:HGNC:11720] | 6483 | 0.031 | 0.4130 | No |
| 46 | STK35 | serine/threonine kinase 35 [Source:HGNC Symbol;Acc:HGNC:16254] | 6512 | 0.027 | 0.4124 | No |
| 47 | EPHA7 | EPH receptor A7 [Source:HGNC Symbol;Acc:HGNC:3390] | 7797 | 0.000 | 0.3777 | No |
| 48 | C9orf131 | chromosome 9 open reading frame 131 [Source:HGNC Symbol;Acc:HGNC:31418] | 7900 | 0.000 | 0.3749 | No |
| 49 | WT1-AS | WT1 antisense RNA [Source:HGNC Symbol;Acc:HGNC:18135] | 8490 | 0.000 | 0.3590 | No |
| 50 | PROX1 | prospero homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9459] | 8725 | 0.000 | 0.3527 | No |
| 51 | JPH1 | junctophilin 1 [Source:HGNC Symbol;Acc:HGNC:14201] | 8835 | 0.000 | 0.3497 | No |
| 52 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8939 | 0.000 | 0.3469 | No |
| 53 | KCNH5 | potassium voltage-gated channel subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:6254] | 10075 | 0.000 | 0.3162 | No |
| 54 | KCNJ1 | potassium inwardly rectifying channel subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:6255] | 10137 | 0.000 | 0.3146 | No |
| 55 | ELF5 | E74 like ETS transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3320] | 10280 | 0.000 | 0.3107 | No |
| 56 | NEDD4 | NEDD4 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7727] | 10759 | 0.000 | 0.2978 | No |
| 57 | RTL3 | retrotransposon Gag like 3 [Source:HGNC Symbol;Acc:HGNC:22997] | 10768 | 0.000 | 0.2976 | No |
| 58 | KCTD4 | potassium channel tetramerization domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23227] | 12181 | 0.000 | 0.2594 | No |
| 59 | PDZD9 | PDZ domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28740] | 12197 | 0.000 | 0.2590 | No |
| 60 | LGI1 | leucine rich glioma inactivated 1 [Source:HGNC Symbol;Acc:HGNC:6572] | 12258 | 0.000 | 0.2573 | No |
| 61 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 12854 | 0.000 | 0.2412 | No |
| 62 | ADAMTSL1 | ADAMTS like 1 [Source:HGNC Symbol;Acc:HGNC:14632] | 12858 | 0.000 | 0.2412 | No |
| 63 | ZP3 | zona pellucida glycoprotein 3 [Source:HGNC Symbol;Acc:HGNC:13189] | 14940 | 0.000 | 0.1848 | No |
| 64 | SH2D1A | SH2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:10820] | 16019 | 0.000 | 0.1557 | No |
| 65 | BDNF | brain derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:1033] | 16311 | 0.000 | 0.1478 | No |
| 66 | TIMD4 | T cell immunoglobulin and mucin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25132] | 16345 | 0.000 | 0.1469 | No |
| 67 | DLX2 | distal-less homeobox 2 [Source:HGNC Symbol;Acc:HGNC:2915] | 16846 | 0.000 | 0.1334 | No |
| 68 | SEMA3A | semaphorin 3A [Source:HGNC Symbol;Acc:HGNC:10723] | 17882 | 0.000 | 0.1054 | No |
| 69 | OTX2 | orthodenticle homeobox 2 [Source:HGNC Symbol;Acc:HGNC:8522] | 19407 | 0.000 | 0.0641 | No |
| 70 | OTX1 | orthodenticle homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8521] | 19408 | 0.000 | 0.0641 | No |
| 71 | OTP | orthopedia homeobox [Source:HGNC Symbol;Acc:HGNC:8518] | 19766 | 0.000 | 0.0545 | No |
| 72 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 19937 | 0.000 | 0.0499 | No |
| 73 | KRTAP11-1 | keratin associated protein 11-1 [Source:HGNC Symbol;Acc:HGNC:18922] | 20124 | 0.000 | 0.0448 | No |
| 74 | KRT20 | keratin 20 [Source:HGNC Symbol;Acc:HGNC:20412] | 21936 | 0.000 | -0.0042 | No |
| 75 | CD52 | CD52 molecule [Source:HGNC Symbol;Acc:HGNC:1804] | 23021 | 0.000 | -0.0335 | No |
| 76 | CPB1 | carboxypeptidase B1 [Source:HGNC Symbol;Acc:HGNC:2299] | 23514 | 0.000 | -0.0468 | No |
| 77 | LAMA4 | laminin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484] | 23756 | 0.000 | -0.0533 | No |
| 78 | WNT8B | Wnt family member 8B [Source:HGNC Symbol;Acc:HGNC:12789] | 24109 | 0.000 | -0.0629 | No |
| 79 | NCKAP5 | NCK associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29847] | 24453 | 0.000 | -0.0721 | No |
| 80 | WNT4 | Wnt family member 4 [Source:HGNC Symbol;Acc:HGNC:12783] | 25127 | 0.000 | -0.0903 | No |
| 81 | SMPX | small muscle protein X-linked [Source:HGNC Symbol;Acc:HGNC:11122] | 25496 | 0.000 | -0.1003 | No |
| 82 | LRRTM3 | leucine rich repeat transmembrane neuronal 3 [Source:HGNC Symbol;Acc:HGNC:19410] | 25680 | 0.000 | -0.1053 | No |
| 83 | FIGN | fidgetin, microtubule severing factor [Source:HGNC Symbol;Acc:HGNC:13285] | 26075 | 0.000 | -0.1159 | No |
| 84 | SOX5 | SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201] | 26148 | 0.000 | -0.1179 | No |
| 85 | MIR7-3HG | MIR7-3 host gene [Source:HGNC Symbol;Acc:HGNC:30049] | 26461 | 0.000 | -0.1263 | No |
| 86 | USP54 | ubiquitin specific peptidase 54 [Source:HGNC Symbol;Acc:HGNC:23513] | 27568 | -0.017 | -0.1561 | No |
| 87 | RWDD1 | RWD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20993] | 27578 | -0.018 | -0.1562 | No |
| 88 | ADNP | activity dependent neuroprotector homeobox [Source:HGNC Symbol;Acc:HGNC:15766] | 27641 | -0.026 | -0.1576 | No |
| 89 | EEF1B2 | eukaryotic translation elongation factor 1 beta 2 [Source:HGNC Symbol;Acc:HGNC:3208] | 28028 | -0.070 | -0.1674 | No |
| 90 | NIPBL | NIPBL cohesin loading factor [Source:HGNC Symbol;Acc:HGNC:28862] | 28284 | -0.105 | -0.1734 | No |
| 91 | AMY2A | amylase alpha 2A [Source:HGNC Symbol;Acc:HGNC:477] | 28356 | -0.113 | -0.1743 | No |
| 92 | FSTL5 | follistatin like 5 [Source:HGNC Symbol;Acc:HGNC:21386] | 28676 | -0.147 | -0.1817 | No |
| 93 | MPC2 | mitochondrial pyruvate carrier 2 [Source:HGNC Symbol;Acc:HGNC:24515] | 28721 | -0.152 | -0.1815 | No |
| 94 | TRIM63 | tripartite motif containing 63 [Source:HGNC Symbol;Acc:HGNC:16007] | 28776 | -0.159 | -0.1816 | No |
| 95 | EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 [Source:HGNC Symbol;Acc:HGNC:16687] | 28843 | -0.169 | -0.1819 | No |
| 96 | ST13 | ST13 Hsp70 interacting protein [Source:HGNC Symbol;Acc:HGNC:11343] | 29069 | -0.197 | -0.1863 | No |
| 97 | FBXO9 | F-box protein 9 [Source:HGNC Symbol;Acc:HGNC:13588] | 29798 | -0.288 | -0.2034 | No |
| 98 | LUC7L3 | LUC7 like 3 pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:24309] | 30016 | -0.315 | -0.2065 | No |
| 99 | ARHGAP6 | Rho GTPase activating protein 6 [Source:HGNC Symbol;Acc:HGNC:676] | 30291 | -0.349 | -0.2109 | No |
| 100 | SREK1 | splicing regulatory glutamic acid and lysine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:17882] | 30330 | -0.355 | -0.2088 | No |
| 101 | IKZF2 | IKAROS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13177] | 30624 | -0.395 | -0.2133 | No |
| 102 | UBE2B | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | 30747 | -0.415 | -0.2129 | No |
| 103 | SCNN1A | sodium channel epithelial 1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:10599] | 30901 | -0.437 | -0.2132 | No |
| 104 | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing [Source:HGNC Symbol;Acc:HGNC:29289] | 31129 | -0.470 | -0.2152 | No |
| 105 | ELMO1 | engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286] | 31237 | -0.490 | -0.2138 | No |
| 106 | ZNF395 | zinc finger protein 395 [Source:HGNC Symbol;Acc:HGNC:18737] | 32017 | -0.617 | -0.2295 | No |
| 107 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 32268 | -0.669 | -0.2304 | No |
| 108 | CD101 | CD101 molecule [Source:HGNC Symbol;Acc:HGNC:5949] | 32323 | -0.682 | -0.2258 | No |
| 109 | FRA10AC1 | FRA10A associated CGG repeat 1 [Source:HGNC Symbol;Acc:HGNC:1162] | 32387 | -0.695 | -0.2214 | No |
| 110 | TBL1XR1 | TBL1X receptor 1 [Source:HGNC Symbol;Acc:HGNC:29529] | 32412 | -0.702 | -0.2159 | No |
| 111 | KHDRBS1 | KH RNA binding domain containing, signal transduction associated 1 [Source:HGNC Symbol;Acc:HGNC:18116] | 32430 | -0.706 | -0.2102 | No |
| 112 | NDST2 | N-deacetylase and N-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:7681] | 32466 | -0.715 | -0.2049 | No |
| 113 | SDC1 | syndecan 1 [Source:HGNC Symbol;Acc:HGNC:10658] | 32707 | -0.771 | -0.2046 | No |
| 114 | ITGA6 | integrin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142] | 32986 | -0.838 | -0.2047 | No |
| 115 | RNF38 | ring finger protein 38 [Source:HGNC Symbol;Acc:HGNC:18052] | 33186 | -0.890 | -0.2023 | No |
| 116 | RANBP9 | RAN binding protein 9 [Source:HGNC Symbol;Acc:HGNC:13727] | 33315 | -0.928 | -0.1976 | No |
| 117 | NSD1 | nuclear receptor binding SET domain protein 1 [Source:HGNC Symbol;Acc:HGNC:14234] | 33325 | -0.930 | -0.1897 | No |
| 118 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 33440 | -0.958 | -0.1844 | No |
| 119 | ZNF654 | zinc finger protein 654 [Source:HGNC Symbol;Acc:HGNC:25612] | 33519 | -0.978 | -0.1779 | No |
| 120 | NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707] | 33652 | -1.018 | -0.1725 | No |
| 121 | ZMYND8 | zinc finger MYND-type containing 8 [Source:HGNC Symbol;Acc:HGNC:9397] | 33845 | -1.066 | -0.1683 | No |
| 122 | TNS2 | tensin 2 [Source:HGNC Symbol;Acc:HGNC:19737] | 33924 | -1.086 | -0.1609 | No |
| 123 | SLC7A8 | solute carrier family 7 member 8 [Source:HGNC Symbol;Acc:HGNC:11066] | 33995 | -1.115 | -0.1530 | No |
| 124 | KLHL5 | kelch like family member 5 [Source:HGNC Symbol;Acc:HGNC:6356] | 34570 | -1.320 | -0.1570 | No |
| 125 | UVRAG | UV radiation resistance associated [Source:HGNC Symbol;Acc:HGNC:12640] | 35094 | -1.566 | -0.1574 | No |
| 126 | ZNF277 | zinc finger protein 277 [Source:HGNC Symbol;Acc:HGNC:13070] | 35138 | -1.587 | -0.1446 | No |
| 127 | SPTBN1 | spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275] | 35515 | -1.800 | -0.1389 | No |
| 128 | ADCY6 | adenylate cyclase 6 [Source:HGNC Symbol;Acc:HGNC:237] | 35649 | -1.885 | -0.1260 | No |
| 129 | DLG3 | discs large MAGUK scaffold protein 3 [Source:HGNC Symbol;Acc:HGNC:2902] | 35667 | -1.902 | -0.1097 | No |
| 130 | RERE | arginine-glutamic acid dipeptide repeats [Source:HGNC Symbol;Acc:HGNC:9965] | 35742 | -1.956 | -0.0946 | No |
| 131 | ZFHX4 | zinc finger homeobox 4 [Source:HGNC Symbol;Acc:HGNC:30939] | 36308 | -2.432 | -0.0885 | No |
| 132 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 36333 | -2.463 | -0.0675 | No |
| 133 | HAUS4 | HAUS augmin like complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:20163] | 36694 | -2.986 | -0.0510 | No |
| 134 | PYGM | glycogen phosphorylase, muscle associated [Source:HGNC Symbol;Acc:HGNC:9726] | 36705 | -3.001 | -0.0249 | No |
| 135 | PACS1 | phosphofurin acidic cluster sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:30032] | 37028 | -4.021 | 0.0017 | No |
