Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | SRF_01 |
| Enrichment Score (ES) | 0.61218417 |
| Normalized Enrichment Score (NES) | 1.4061168 |
| Nominal p-value | 0.024630541 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.999 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 20 | 4.680 | 0.0853 | Yes |
| 2 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 125 | 3.424 | 0.1453 | Yes |
| 3 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797] | 160 | 3.237 | 0.2038 | Yes |
| 4 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 218 | 2.944 | 0.2563 | Yes |
| 5 | ACTN1 | actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163] | 398 | 2.362 | 0.2948 | Yes |
| 6 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 530 | 2.034 | 0.3285 | Yes |
| 7 | WDR1 | WD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754] | 531 | 2.034 | 0.3659 | Yes |
| 8 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 587 | 1.948 | 0.4001 | Yes |
| 9 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 639 | 1.855 | 0.4328 | Yes |
| 10 | ACTR3 | actin related protein 3 [Source:HGNC Symbol;Acc:HGNC:170] | 731 | 1.705 | 0.4616 | Yes |
| 11 | HOXB4 | homeobox B4 [Source:HGNC Symbol;Acc:HGNC:5115] | 843 | 1.575 | 0.4875 | Yes |
| 12 | CFL1 | cofilin 1 [Source:HGNC Symbol;Acc:HGNC:1874] | 889 | 1.537 | 0.5145 | Yes |
| 13 | MYL6 | myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587] | 943 | 1.485 | 0.5403 | Yes |
| 14 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 966 | 1.461 | 0.5665 | Yes |
| 15 | MYH11 | myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569] | 1274 | 1.234 | 0.5808 | Yes |
| 16 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 1723 | 1.015 | 0.5874 | Yes |
| 17 | ASB2 | ankyrin repeat and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:16012] | 1725 | 1.014 | 0.6059 | Yes |
| 18 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 2388 | 0.757 | 0.6019 | Yes |
| 19 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 2607 | 0.693 | 0.6088 | Yes |
| 20 | CNN2 | calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156] | 3215 | 0.540 | 0.6023 | Yes |
| 21 | SCOC | short coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:20335] | 3480 | 0.484 | 0.6041 | Yes |
| 22 | TGFB1I1 | transforming growth factor beta 1 induced transcript 1 [Source:HGNC Symbol;Acc:HGNC:11767] | 3588 | 0.464 | 0.6097 | Yes |
| 23 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3826 | 0.420 | 0.6110 | Yes |
| 24 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 [Source:HGNC Symbol;Acc:HGNC:7237] | 4042 | 0.382 | 0.6122 | Yes |
| 25 | ITGB1BP2 | integrin subunit beta 1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6154] | 5462 | 0.160 | 0.5768 | No |
| 26 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6285] | 6308 | 0.051 | 0.5549 | No |
| 27 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8456 | 0.000 | 0.4970 | No |
| 28 | CALD1 | caldesmon 1 [Source:HGNC Symbol;Acc:HGNC:1441] | 9083 | 0.000 | 0.4801 | No |
| 29 | NPAS4 | neuronal PAS domain protein 4 [Source:HGNC Symbol;Acc:HGNC:18983] | 10083 | 0.000 | 0.4531 | No |
| 30 | SUSD1 | sushi domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25413] | 10526 | 0.000 | 0.4412 | No |
| 31 | PRM1 | protamine 1 [Source:HGNC Symbol;Acc:HGNC:9447] | 11827 | 0.000 | 0.4061 | No |
| 32 | TNMD | tenomodulin [Source:HGNC Symbol;Acc:HGNC:17757] | 15100 | 0.000 | 0.3177 | No |
| 33 | CA3 | carbonic anhydrase 3 [Source:HGNC Symbol;Acc:HGNC:1374] | 15837 | 0.000 | 0.2979 | No |
| 34 | PHOX2B | paired like homeobox 2B [Source:HGNC Symbol;Acc:HGNC:9143] | 16401 | 0.000 | 0.2827 | No |
| 35 | GPR20 | G protein-coupled receptor 20 [Source:HGNC Symbol;Acc:HGNC:4475] | 17526 | 0.000 | 0.2523 | No |
| 36 | STX10 | syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428] | 17705 | 0.000 | 0.2475 | No |
| 37 | IGF2-AS | IGF2 antisense RNA [Source:HGNC Symbol;Acc:HGNC:14062] | 20822 | 0.000 | 0.1634 | No |
| 38 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22265 | 0.000 | 0.1244 | No |
| 39 | IL17B | interleukin 17B [Source:HGNC Symbol;Acc:HGNC:5982] | 27029 | 0.000 | -0.0041 | No |
| 40 | TPM1 | tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010] | 27535 | -0.011 | -0.0176 | No |
| 41 | PRUNE2 | prune homolog 2 with BCH domain [Source:HGNC Symbol;Acc:HGNC:25209] | 28948 | -0.185 | -0.0523 | No |
| 42 | TAZ | tafazzin [Source:HGNC Symbol;Acc:HGNC:11577] | 30326 | -0.355 | -0.0830 | No |
| 43 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 32837 | -0.801 | -0.1361 | No |
| 44 | SETD2 | SET domain containing 2, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:18420] | 33459 | -0.962 | -0.1352 | No |
| 45 | TNNC1 | troponin C1, slow skeletal and cardiac type [Source:HGNC Symbol;Acc:HGNC:11943] | 33948 | -1.096 | -0.1282 | No |
| 46 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 34421 | -1.257 | -0.1179 | No |
| 47 | PLCB3 | phospholipase C beta 3 [Source:HGNC Symbol;Acc:HGNC:9056] | 34607 | -1.334 | -0.0984 | No |
| 48 | MUS81 | MUS81 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:29814] | 35055 | -1.547 | -0.0821 | No |
| 49 | VCL | vinculin [Source:HGNC Symbol;Acc:HGNC:12665] | 35592 | -1.844 | -0.0628 | No |
| 50 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35766 | -1.976 | -0.0312 | No |
| 51 | DIXDC1 | DIX domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23695] | 36947 | -3.647 | 0.0039 | No |
