Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_BUB1B |
| Enrichment Score (ES) | -0.8368555 |
| Normalized Enrichment Score (NES) | -1.6319633 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.002091587 |
| FWER p-Value | 0.034 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1401 | 1.148 | -0.0238 | No |
| 2 | MRPL39 | mitochondrial ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:14027] | 2870 | 0.620 | -0.0558 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26168 | 0.000 | -0.6847 | No |
| 4 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 28442 | -0.123 | -0.7446 | No |
| 5 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29642 | -0.271 | -0.7736 | No |
| 6 | CSE1L | chromosome segregation 1 like [Source:HGNC Symbol;Acc:HGNC:2431] | 30803 | -0.423 | -0.7998 | No |
| 7 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.8180 | No |
| 8 | NUP205 | nucleoporin 205 [Source:HGNC Symbol;Acc:HGNC:18658] | 31996 | -0.612 | -0.8175 | No |
| 9 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32450 | -0.711 | -0.8210 | No |
| 10 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32757 | -0.782 | -0.8197 | No |
| 11 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33395 | -0.948 | -0.8252 | Yes |
| 12 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.8201 | Yes |
| 13 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 33977 | -1.108 | -0.8148 | Yes |
| 14 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.8043 | Yes |
| 15 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 34275 | -1.208 | -0.7939 | Yes |
| 16 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34716 | -1.383 | -0.7889 | Yes |
| 17 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7735 | Yes |
| 18 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34837 | -1.440 | -0.7571 | Yes |
| 19 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34877 | -1.459 | -0.7403 | Yes |
| 20 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 34892 | -1.469 | -0.7227 | Yes |
| 21 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 35102 | -1.571 | -0.7091 | Yes |
| 22 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 35259 | -1.656 | -0.6930 | Yes |
| 23 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35268 | -1.661 | -0.6728 | Yes |
| 24 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35320 | -1.686 | -0.6536 | Yes |
| 25 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35401 | -1.734 | -0.6345 | Yes |
| 26 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35408 | -1.739 | -0.6133 | Yes |
| 27 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35614 | -1.860 | -0.5961 | Yes |
| 28 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.5735 | Yes |
| 29 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35633 | -1.871 | -0.5508 | Yes |
| 30 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 35664 | -1.896 | -0.5284 | Yes |
| 31 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35681 | -1.914 | -0.5053 | Yes |
| 32 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.4838 | Yes |
| 33 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35789 | -1.990 | -0.4595 | Yes |
| 34 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.4387 | Yes |
| 35 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.4126 | Yes |
| 36 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36036 | -2.183 | -0.3865 | Yes |
| 37 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.3598 | Yes |
| 38 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36082 | -2.223 | -0.3336 | Yes |
| 39 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.3067 | Yes |
| 40 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36153 | -2.285 | -0.2800 | Yes |
| 41 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.2526 | Yes |
| 42 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36276 | -2.406 | -0.2254 | Yes |
| 43 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36323 | -2.449 | -0.1966 | Yes |
| 44 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.1671 | Yes |
| 45 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36434 | -2.597 | -0.1371 | Yes |
| 46 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.1074 | Yes |
| 47 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.0713 | Yes |
| 48 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36722 | -3.033 | -0.0353 | Yes |
| 49 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36962 | -3.693 | 0.0035 | Yes |
