Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_CCNA2 |
| Enrichment Score (ES) | -0.8523716 |
| Normalized Enrichment Score (NES) | -1.7411648 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.289026E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1757 | 1.003 | -0.0390 | No |
| 2 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | -0.1566 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26168 | 0.000 | -0.6977 | No |
| 4 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29642 | -0.271 | -0.7892 | No |
| 5 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 30362 | -0.359 | -0.8056 | No |
| 6 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31674 | -0.559 | -0.8363 | No |
| 7 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.8332 | No |
| 8 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32450 | -0.711 | -0.8464 | Yes |
| 9 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32479 | -0.717 | -0.8411 | Yes |
| 10 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32680 | -0.764 | -0.8400 | Yes |
| 11 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32901 | -0.817 | -0.8391 | Yes |
| 12 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33320 | -0.929 | -0.8425 | Yes |
| 13 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33395 | -0.948 | -0.8365 | Yes |
| 14 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 33639 | -1.014 | -0.8345 | Yes |
| 15 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 33654 | -1.019 | -0.8263 | Yes |
| 16 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.8181 | Yes |
| 17 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33831 | -1.063 | -0.8134 | Yes |
| 18 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 33977 | -1.108 | -0.8079 | Yes |
| 19 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.8018 | Yes |
| 20 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34716 | -1.383 | -0.8065 | Yes |
| 21 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7965 | Yes |
| 22 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34837 | -1.440 | -0.7856 | Yes |
| 23 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34852 | -1.446 | -0.7737 | Yes |
| 24 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34877 | -1.459 | -0.7621 | Yes |
| 25 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 34892 | -1.469 | -0.7500 | Yes |
| 26 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.7412 | Yes |
| 27 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35085 | -1.562 | -0.7290 | Yes |
| 28 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35127 | -1.583 | -0.7167 | Yes |
| 29 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 35314 | -1.681 | -0.7075 | Yes |
| 30 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35320 | -1.686 | -0.6934 | Yes |
| 31 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35401 | -1.734 | -0.6809 | Yes |
| 32 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35408 | -1.739 | -0.6664 | Yes |
| 33 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35419 | -1.743 | -0.6520 | Yes |
| 34 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35494 | -1.788 | -0.6389 | Yes |
| 35 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35520 | -1.803 | -0.6243 | Yes |
| 36 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35551 | -1.818 | -0.6098 | Yes |
| 37 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.5960 | Yes |
| 38 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35633 | -1.871 | -0.5804 | Yes |
| 39 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35653 | -1.889 | -0.5649 | Yes |
| 40 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35656 | -1.892 | -0.5490 | Yes |
| 41 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35681 | -1.914 | -0.5335 | Yes |
| 42 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35698 | -1.925 | -0.5177 | Yes |
| 43 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.5033 | Yes |
| 44 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35789 | -1.990 | -0.4865 | Yes |
| 45 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35922 | -2.100 | -0.4723 | Yes |
| 46 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35994 | -2.147 | -0.4561 | Yes |
| 47 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.4379 | Yes |
| 48 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.4201 | Yes |
| 49 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36036 | -2.183 | -0.4023 | Yes |
| 50 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.3839 | Yes |
| 51 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36082 | -2.223 | -0.3662 | Yes |
| 52 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36104 | -2.244 | -0.3479 | Yes |
| 53 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36153 | -2.285 | -0.3299 | Yes |
| 54 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.3113 | Yes |
| 55 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36214 | -2.336 | -0.2921 | Yes |
| 56 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36276 | -2.406 | -0.2735 | Yes |
| 57 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36323 | -2.449 | -0.2540 | Yes |
| 58 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.2340 | Yes |
| 59 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.2133 | Yes |
| 60 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36453 | -2.630 | -0.1927 | Yes |
| 61 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.1730 | Yes |
| 62 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36636 | -2.885 | -0.1489 | Yes |
| 63 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.1250 | Yes |
| 64 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.1001 | Yes |
| 65 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36680 | -2.959 | -0.0752 | Yes |
| 66 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36808 | -3.196 | -0.0516 | Yes |
| 67 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36860 | -3.318 | -0.0250 | Yes |
| 68 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36962 | -3.693 | 0.0035 | Yes |
