Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_CDC20 |
| Enrichment Score (ES) | -0.8257458 |
| Normalized Enrichment Score (NES) | -1.64596 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0017924792 |
| FWER p-Value | 0.023 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | UBE2S | ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895] | 526 | 2.037 | 0.0073 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1757 | 1.003 | -0.0153 | No |
| 3 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 3354 | 0.511 | -0.0530 | No |
| 4 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 5637 | 0.136 | -0.1131 | No |
| 5 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | -0.1258 | No |
| 6 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26168 | 0.000 | -0.6667 | No |
| 7 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31674 | -0.559 | -0.8094 | No |
| 8 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.8051 | No |
| 9 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 32153 | -0.642 | -0.8095 | No |
| 10 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32450 | -0.711 | -0.8100 | No |
| 11 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32522 | -0.726 | -0.8042 | No |
| 12 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33320 | -0.929 | -0.8159 | Yes |
| 13 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33395 | -0.948 | -0.8079 | Yes |
| 14 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 33639 | -1.014 | -0.8037 | Yes |
| 15 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.7938 | Yes |
| 16 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33831 | -1.063 | -0.7868 | Yes |
| 17 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 33977 | -1.108 | -0.7790 | Yes |
| 18 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.7704 | Yes |
| 19 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7738 | Yes |
| 20 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34837 | -1.440 | -0.7598 | Yes |
| 21 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34877 | -1.459 | -0.7455 | Yes |
| 22 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.7338 | Yes |
| 23 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35085 | -1.562 | -0.7182 | Yes |
| 24 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35127 | -1.583 | -0.7026 | Yes |
| 25 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 35259 | -1.656 | -0.6886 | Yes |
| 26 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35320 | -1.686 | -0.6724 | Yes |
| 27 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35408 | -1.739 | -0.6564 | Yes |
| 28 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35419 | -1.743 | -0.6382 | Yes |
| 29 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35520 | -1.803 | -0.6218 | Yes |
| 30 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35551 | -1.818 | -0.6034 | Yes |
| 31 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35561 | -1.824 | -0.5844 | Yes |
| 32 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.5664 | Yes |
| 33 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35633 | -1.871 | -0.5468 | Yes |
| 34 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35656 | -1.892 | -0.5274 | Yes |
| 35 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35681 | -1.914 | -0.5078 | Yes |
| 36 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35698 | -1.925 | -0.4879 | Yes |
| 37 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.4692 | Yes |
| 38 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35789 | -1.990 | -0.4482 | Yes |
| 39 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.4310 | Yes |
| 40 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.4086 | Yes |
| 41 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36036 | -2.183 | -0.3861 | Yes |
| 42 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.3631 | Yes |
| 43 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.3410 | Yes |
| 44 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36153 | -2.285 | -0.3182 | Yes |
| 45 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36164 | -2.301 | -0.2942 | Yes |
| 46 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.2704 | Yes |
| 47 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36214 | -2.336 | -0.2462 | Yes |
| 48 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36276 | -2.406 | -0.2224 | Yes |
| 49 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.1984 | Yes |
| 50 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.1723 | Yes |
| 51 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36453 | -2.630 | -0.1460 | Yes |
| 52 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.1203 | Yes |
| 53 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.0904 | Yes |
| 54 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.0592 | Yes |
| 55 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36680 | -2.959 | -0.0280 | Yes |
| 56 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36962 | -3.693 | 0.0035 | Yes |
