Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_CENPF |
| Enrichment Score (ES) | -0.81887835 |
| Normalized Enrichment Score (NES) | -1.6512703 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.00200408 |
| FWER p-Value | 0.021 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | UBE2S | ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895] | 526 | 2.037 | 0.0058 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1757 | 1.003 | -0.0176 | No |
| 3 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 5637 | 0.136 | -0.1210 | No |
| 4 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | -0.1337 | No |
| 5 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26168 | 0.000 | -0.6747 | No |
| 6 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29642 | -0.271 | -0.7658 | No |
| 7 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 31608 | -0.550 | -0.8135 | Yes |
| 8 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31674 | -0.559 | -0.8097 | Yes |
| 9 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.8059 | Yes |
| 10 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 31752 | -0.570 | -0.8006 | Yes |
| 11 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 32153 | -0.642 | -0.8051 | Yes |
| 12 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32479 | -0.717 | -0.8068 | Yes |
| 13 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32522 | -0.726 | -0.8008 | Yes |
| 14 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 32563 | -0.736 | -0.7947 | Yes |
| 15 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32680 | -0.764 | -0.7903 | Yes |
| 16 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33320 | -0.929 | -0.7985 | Yes |
| 17 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33395 | -0.948 | -0.7911 | Yes |
| 18 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 33654 | -1.019 | -0.7881 | Yes |
| 19 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.7785 | Yes |
| 20 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33831 | -1.063 | -0.7723 | Yes |
| 21 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 34075 | -1.137 | -0.7677 | Yes |
| 22 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.7574 | Yes |
| 23 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34716 | -1.383 | -0.7601 | Yes |
| 24 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 34764 | -1.403 | -0.7476 | Yes |
| 25 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7344 | Yes |
| 26 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34877 | -1.459 | -0.7224 | Yes |
| 27 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.7119 | Yes |
| 28 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35085 | -1.562 | -0.6975 | Yes |
| 29 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35127 | -1.583 | -0.6830 | Yes |
| 30 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35401 | -1.734 | -0.6734 | Yes |
| 31 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35408 | -1.739 | -0.6565 | Yes |
| 32 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35419 | -1.743 | -0.6396 | Yes |
| 33 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35494 | -1.788 | -0.6241 | Yes |
| 34 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35520 | -1.803 | -0.6070 | Yes |
| 35 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35551 | -1.818 | -0.5900 | Yes |
| 36 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.5737 | Yes |
| 37 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35633 | -1.871 | -0.5555 | Yes |
| 38 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35656 | -1.892 | -0.5375 | Yes |
| 39 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35698 | -1.925 | -0.5197 | Yes |
| 40 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.5025 | Yes |
| 41 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35789 | -1.990 | -0.4830 | Yes |
| 42 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 35895 | -2.079 | -0.4654 | Yes |
| 43 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35922 | -2.100 | -0.4455 | Yes |
| 44 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35994 | -2.147 | -0.4263 | Yes |
| 45 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.4052 | Yes |
| 46 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.3845 | Yes |
| 47 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.3637 | Yes |
| 48 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36065 | -2.205 | -0.3427 | Yes |
| 49 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36104 | -2.244 | -0.3217 | Yes |
| 50 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.3012 | Yes |
| 51 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36214 | -2.336 | -0.2789 | Yes |
| 52 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36261 | -2.395 | -0.2566 | Yes |
| 53 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.2348 | Yes |
| 54 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.2106 | Yes |
| 55 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36453 | -2.630 | -0.1864 | Yes |
| 56 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.1628 | Yes |
| 57 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36636 | -2.885 | -0.1347 | Yes |
| 58 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36648 | -2.896 | -0.1066 | Yes |
| 59 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.0783 | Yes |
| 60 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.0493 | Yes |
| 61 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36680 | -2.959 | -0.0203 | Yes |
| 62 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36808 | -3.196 | 0.0076 | Yes |
