Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_RRM2 |
| Enrichment Score (ES) | -0.88188624 |
| Normalized Enrichment Score (NES) | -1.6699767 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0017201254 |
| FWER p-Value | 0.012 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | -0.1646 | No |
| 2 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26168 | 0.000 | -0.7053 | No |
| 3 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.8478 | No |
| 4 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32757 | -0.782 | -0.8647 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33395 | -0.948 | -0.8690 | Yes |
| 6 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.8625 | Yes |
| 7 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33831 | -1.063 | -0.8523 | Yes |
| 8 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 33977 | -1.108 | -0.8412 | Yes |
| 9 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.8292 | Yes |
| 10 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 34275 | -1.208 | -0.8172 | Yes |
| 11 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34716 | -1.383 | -0.8103 | Yes |
| 12 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7930 | Yes |
| 13 | SMC1A | structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111] | 34805 | -1.420 | -0.7741 | Yes |
| 14 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34837 | -1.440 | -0.7553 | Yes |
| 15 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34877 | -1.459 | -0.7366 | Yes |
| 16 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35320 | -1.686 | -0.7256 | Yes |
| 17 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35520 | -1.803 | -0.7064 | Yes |
| 18 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35551 | -1.818 | -0.6825 | Yes |
| 19 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.6592 | Yes |
| 20 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35633 | -1.871 | -0.6339 | Yes |
| 21 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35656 | -1.892 | -0.6088 | Yes |
| 22 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35681 | -1.914 | -0.5834 | Yes |
| 23 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35698 | -1.925 | -0.5577 | Yes |
| 24 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.5330 | Yes |
| 25 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35789 | -1.990 | -0.5060 | Yes |
| 26 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.4823 | Yes |
| 27 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36036 | -2.183 | -0.4537 | Yes |
| 28 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.4241 | Yes |
| 29 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.3953 | Yes |
| 30 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36153 | -2.285 | -0.3656 | Yes |
| 31 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.3351 | Yes |
| 32 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.3057 | Yes |
| 33 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.2719 | Yes |
| 34 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36453 | -2.630 | -0.2378 | Yes |
| 35 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.2034 | Yes |
| 36 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.1645 | Yes |
| 37 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.1244 | Yes |
| 38 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36680 | -2.959 | -0.0843 | Yes |
| 39 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36860 | -3.318 | -0.0440 | Yes |
| 40 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36962 | -3.693 | 0.0035 | Yes |
