Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | MODULE_121 |
| Enrichment Score (ES) | 0.61750704 |
| Normalized Enrichment Score (NES) | 1.5642937 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.16010173 |
| FWER p-Value | 0.765 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.925 | 0.0461 | Yes |
| 2 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 2 | 4.920 | 0.0922 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 5 | 4.859 | 0.1377 | Yes |
| 4 | VEGFC | vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682] | 11 | 4.811 | 0.1826 | Yes |
| 5 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 20 | 4.680 | 0.2262 | Yes |
| 6 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 34 | 4.388 | 0.2670 | Yes |
| 7 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 51 | 4.081 | 0.3048 | Yes |
| 8 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 94 | 3.654 | 0.3379 | Yes |
| 9 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 155 | 3.255 | 0.3668 | Yes |
| 10 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 172 | 3.156 | 0.3959 | Yes |
| 11 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 177 | 3.142 | 0.4252 | Yes |
| 12 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 276 | 2.675 | 0.4476 | Yes |
| 13 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 540 | 2.025 | 0.4595 | Yes |
| 14 | TSPAN3 | tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752] | 544 | 2.022 | 0.4783 | Yes |
| 15 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 630 | 1.872 | 0.4936 | Yes |
| 16 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 665 | 1.804 | 0.5096 | Yes |
| 17 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 972 | 1.450 | 0.5149 | Yes |
| 18 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 1028 | 1.414 | 0.5266 | Yes |
| 19 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 1102 | 1.360 | 0.5374 | Yes |
| 20 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 1138 | 1.335 | 0.5490 | Yes |
| 21 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1162 | 1.317 | 0.5607 | Yes |
| 22 | HBEGF | heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] | 1193 | 1.295 | 0.5720 | Yes |
| 23 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1257 | 1.250 | 0.5820 | Yes |
| 24 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 1404 | 1.146 | 0.5888 | Yes |
| 25 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1415 | 1.142 | 0.5992 | Yes |
| 26 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 1571 | 1.078 | 0.6051 | Yes |
| 27 | MXD1 | MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] | 1595 | 1.071 | 0.6145 | Yes |
| 28 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 1903 | 0.944 | 0.6151 | Yes |
| 29 | ZEB1 | zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642] | 2110 | 0.853 | 0.6175 | Yes |
| 30 | PSPHP1 | phosphoserine phosphatase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9578] | 2679 | 0.667 | 0.6084 | No |
| 31 | EPHB4 | EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395] | 3729 | 0.435 | 0.5841 | No |
| 32 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 3911 | 0.405 | 0.5830 | No |
| 33 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 4064 | 0.379 | 0.5825 | No |
| 34 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 4195 | 0.357 | 0.5823 | No |
| 35 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 4296 | 0.340 | 0.5828 | No |
| 36 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 4313 | 0.337 | 0.5855 | No |
| 37 | MST1R | macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381] | 4355 | 0.330 | 0.5875 | No |
| 38 | FGA | fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661] | 4877 | 0.251 | 0.5758 | No |
| 39 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 4880 | 0.250 | 0.5780 | No |
| 40 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4960 | 0.237 | 0.5781 | No |
| 41 | FGB | fibrinogen beta chain [Source:HGNC Symbol;Acc:HGNC:3662] | 5156 | 0.208 | 0.5748 | No |
| 42 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 5503 | 0.153 | 0.5669 | No |
| 43 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6745 | 0.000 | 0.5333 | No |
| 44 | AREG | amphiregulin [Source:HGNC Symbol;Acc:HGNC:651] | 7658 | 0.000 | 0.5087 | No |
| 45 | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 7876 | 0.000 | 0.5028 | No |
| 46 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9175 | 0.000 | 0.4677 | No |
| 47 | GRPR | gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609] | 10313 | 0.000 | 0.4370 | No |
| 48 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11243 | 0.000 | 0.4119 | No |
| 49 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12687 | 0.000 | 0.3729 | No |
| 50 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12703 | 0.000 | 0.3725 | No |
| 51 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12704 | 0.000 | 0.3725 | No |
| 52 | VIP | vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693] | 13386 | 0.000 | 0.3541 | No |
| 53 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13989 | 0.000 | 0.3378 | No |
| 54 | IL15RA | interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978] | 14345 | 0.000 | 0.3282 | No |
| 55 | TACSTD2 | tumor associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:HGNC:11530] | 14656 | 0.000 | 0.3198 | No |
| 56 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15868 | 0.000 | 0.2871 | No |
| 57 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15869 | 0.000 | 0.2871 | No |
| 58 | FGG | fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694] | 16761 | 0.000 | 0.2630 | No |
| 59 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16989 | 0.000 | 0.2568 | No |
| 60 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17115 | 0.000 | 0.2535 | No |
| 61 | IL3 | interleukin 3 [Source:HGNC Symbol;Acc:HGNC:6011] | 17751 | 0.000 | 0.2363 | No |
| 62 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18989 | 0.000 | 0.2029 | No |
| 63 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19438 | 0.000 | 0.1907 | No |
| 64 | PTN | pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] | 20088 | 0.000 | 0.1732 | No |
| 65 | EDNRA | endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] | 21901 | 0.000 | 0.1242 | No |
| 66 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22265 | 0.000 | 0.1144 | No |
| 67 | SLAMF1 | signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903] | 22986 | 0.000 | 0.0949 | No |
| 68 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 23102 | 0.000 | 0.0918 | No |
| 69 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 23103 | 0.000 | 0.0918 | No |
| 70 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24539 | 0.000 | 0.0530 | No |
| 71 | FGF4 | fibroblast growth factor 4 [Source:HGNC Symbol;Acc:HGNC:3682] | 25419 | 0.000 | 0.0293 | No |
| 72 | REG1B | regenerating family member 1 beta [Source:HGNC Symbol;Acc:HGNC:9952] | 26389 | 0.000 | 0.0031 | No |
| 73 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27091 | 0.000 | -0.0159 | No |
| 74 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 28245 | -0.101 | -0.0461 | No |
| 75 | VIPR1 | vasoactive intestinal peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:12694] | 28520 | -0.131 | -0.0523 | No |
| 76 | TGFB3 | transforming growth factor beta 3 [Source:HGNC Symbol;Acc:HGNC:11769] | 29614 | -0.267 | -0.0793 | No |
| 77 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 29635 | -0.270 | -0.0773 | No |
| 78 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 30086 | -0.322 | -0.0865 | No |
| 79 | CCN1 | cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654] | 30109 | -0.325 | -0.0840 | No |
| 80 | GRN | granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601] | 31454 | -0.521 | -0.1155 | No |
| 81 | CRIP1 | cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360] | 31631 | -0.553 | -0.1150 | No |
| 82 | BCAR1 | BCAR1 scaffold protein, Cas family member [Source:HGNC Symbol;Acc:HGNC:971] | 32103 | -0.631 | -0.1219 | No |
| 83 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 32838 | -0.801 | -0.1342 | No |
| 84 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 32952 | -0.829 | -0.1295 | No |
| 85 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 33019 | -0.846 | -0.1233 | No |
| 86 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 34037 | -1.127 | -0.1403 | No |
| 87 | CSRP2 | cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470] | 34487 | -1.288 | -0.1403 | No |
| 88 | SFN | stratifin [Source:HGNC Symbol;Acc:HGNC:10773] | 34812 | -1.424 | -0.1358 | No |
| 89 | RUNX3 | RUNX family transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473] | 34908 | -1.474 | -0.1245 | No |
| 90 | INSIG1 | insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] | 34974 | -1.500 | -0.1122 | No |
| 91 | LRP1 | LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692] | 35000 | -1.518 | -0.0987 | No |
| 92 | GAS6 | growth arrest specific 6 [Source:HGNC Symbol;Acc:HGNC:4168] | 35248 | -1.649 | -0.0899 | No |
| 93 | CREG1 | cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351] | 35340 | -1.696 | -0.0765 | No |
| 94 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 35364 | -1.711 | -0.0611 | No |
| 95 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 35761 | -1.973 | -0.0533 | No |
| 96 | MAPRE2 | microtubule associated protein RP/EB family member 2 [Source:HGNC Symbol;Acc:HGNC:6891] | 35824 | -2.016 | -0.0361 | No |
| 97 | EPS8 | epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420] | 36227 | -2.349 | -0.0249 | No |
| 98 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36356 | -2.490 | -0.0051 | No |
| 99 | ZFP36L2 | ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108] | 36486 | -2.658 | 0.0163 | No |
