Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | MODULE_158 |
| Enrichment Score (ES) | -0.81489617 |
| Normalized Enrichment Score (NES) | -1.5902605 |
| Nominal p-value | 0.0013495276 |
| FDR q-value | 0.0066184113 |
| FWER p-Value | 0.144 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | S100A11 | S100 calcium binding protein A11 [Source:HGNC Symbol;Acc:HGNC:10488] | 411 | 2.327 | 0.0189 | No |
| 2 | TENT4A | terminal nucleotidyltransferase 4A [Source:HGNC Symbol;Acc:HGNC:16705] | 707 | 1.749 | 0.0335 | No |
| 3 | SSBP1 | single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317] | 5253 | 0.193 | -0.0866 | No |
| 4 | ORC1 | origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487] | 5294 | 0.186 | -0.0853 | No |
| 5 | TERT | telomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730] | 6009 | 0.086 | -0.1035 | No |
| 6 | NAP1L1 | nucleosome assembly protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:7637] | 29354 | -0.233 | -0.7306 | No |
| 7 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32479 | -0.717 | -0.8056 | Yes |
| 8 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32680 | -0.764 | -0.8012 | Yes |
| 9 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 33160 | -0.882 | -0.8027 | Yes |
| 10 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 33164 | -0.884 | -0.7914 | Yes |
| 11 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33638 | -1.014 | -0.7911 | Yes |
| 12 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33831 | -1.063 | -0.7825 | Yes |
| 13 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.7753 | Yes |
| 14 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34224 | -1.190 | -0.7630 | Yes |
| 15 | DDX11 | DEAD/H-box helicase 11 [Source:HGNC Symbol;Acc:HGNC:2736] | 34688 | -1.368 | -0.7578 | Yes |
| 16 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34716 | -1.383 | -0.7407 | Yes |
| 17 | POLD2 | DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176] | 34769 | -1.405 | -0.7239 | Yes |
| 18 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34852 | -1.446 | -0.7075 | Yes |
| 19 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 35234 | -1.641 | -0.6966 | Yes |
| 20 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 35321 | -1.686 | -0.6771 | Yes |
| 21 | CHAF1A | chromatin assembly factor 1 subunit A [Source:HGNC Symbol;Acc:HGNC:1910] | 35426 | -1.748 | -0.6574 | Yes |
| 22 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35533 | -1.810 | -0.6369 | Yes |
| 23 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.6153 | Yes |
| 24 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35643 | -1.882 | -0.5914 | Yes |
| 25 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 35686 | -1.917 | -0.5678 | Yes |
| 26 | RNASEH2A | ribonuclease H2 subunit A [Source:HGNC Symbol;Acc:HGNC:18518] | 35715 | -1.936 | -0.5436 | Yes |
| 27 | BLM | BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:1058] | 35779 | -1.982 | -0.5197 | Yes |
| 28 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35922 | -2.100 | -0.4964 | Yes |
| 29 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35994 | -2.147 | -0.4706 | Yes |
| 30 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.4429 | Yes |
| 31 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35999 | -2.149 | -0.4152 | Yes |
| 32 | POLA1 | DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173] | 36270 | -2.402 | -0.3915 | Yes |
| 33 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 36291 | -2.418 | -0.3609 | Yes |
| 34 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36417 | -2.569 | -0.3311 | Yes |
| 35 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36434 | -2.597 | -0.2980 | Yes |
| 36 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36453 | -2.630 | -0.2645 | Yes |
| 37 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36539 | -2.738 | -0.2315 | Yes |
| 38 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36551 | -2.763 | -0.1961 | Yes |
| 39 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.1613 | Yes |
| 40 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36769 | -3.134 | -0.1234 | Yes |
| 41 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36816 | -3.214 | -0.0831 | Yes |
| 42 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36860 | -3.318 | -0.0415 | Yes |
| 43 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36962 | -3.693 | 0.0035 | Yes |
