Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | MODULE_345 |
| Enrichment Score (ES) | 0.65221393 |
| Normalized Enrichment Score (NES) | 1.7110934 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07580836 |
| FWER p-Value | 0.169 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 5 | 4.859 | 0.0430 | Yes |
| 2 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 21 | 4.639 | 0.0838 | Yes |
| 3 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 33 | 4.396 | 0.1225 | Yes |
| 4 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 53 | 4.050 | 0.1579 | Yes |
| 5 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 74 | 3.816 | 0.1913 | Yes |
| 6 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 77 | 3.799 | 0.2249 | Yes |
| 7 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 86 | 3.723 | 0.2578 | Yes |
| 8 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 133 | 3.364 | 0.2864 | Yes |
| 9 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 143 | 3.299 | 0.3154 | Yes |
| 10 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 206 | 3.020 | 0.3406 | Yes |
| 11 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 220 | 2.934 | 0.3662 | Yes |
| 12 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 236 | 2.845 | 0.3911 | Yes |
| 13 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 246 | 2.791 | 0.4156 | Yes |
| 14 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 296 | 2.608 | 0.4375 | Yes |
| 15 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 353 | 2.469 | 0.4579 | Yes |
| 16 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 425 | 2.282 | 0.4762 | Yes |
| 17 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 438 | 2.255 | 0.4959 | Yes |
| 18 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 467 | 2.166 | 0.5144 | Yes |
| 19 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 533 | 2.033 | 0.5306 | Yes |
| 20 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 871 | 1.549 | 0.5353 | Yes |
| 21 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 873 | 1.548 | 0.5490 | Yes |
| 22 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 985 | 1.441 | 0.5588 | Yes |
| 23 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1257 | 1.250 | 0.5625 | Yes |
| 24 | BLNK | B cell linker [Source:HGNC Symbol;Acc:HGNC:14211] | 1286 | 1.224 | 0.5726 | Yes |
| 25 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 1308 | 1.207 | 0.5828 | Yes |
| 26 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 1314 | 1.202 | 0.5933 | Yes |
| 27 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1349 | 1.178 | 0.6029 | Yes |
| 28 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 1406 | 1.146 | 0.6115 | Yes |
| 29 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 1423 | 1.140 | 0.6212 | Yes |
| 30 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 1446 | 1.128 | 0.6306 | Yes |
| 31 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 1486 | 1.111 | 0.6394 | Yes |
| 32 | ZNF436 | zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] | 1727 | 1.013 | 0.6419 | Yes |
| 33 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1993 | 0.902 | 0.6428 | Yes |
| 34 | UNC13B | unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] | 2158 | 0.833 | 0.6457 | Yes |
| 35 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 2607 | 0.693 | 0.6398 | Yes |
| 36 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 2641 | 0.682 | 0.6449 | Yes |
| 37 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2792 | 0.640 | 0.6465 | Yes |
| 38 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 2954 | 0.600 | 0.6475 | Yes |
| 39 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 3194 | 0.547 | 0.6459 | Yes |
| 40 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 3294 | 0.524 | 0.6479 | Yes |
| 41 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 3306 | 0.522 | 0.6522 | Yes |
| 42 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 3753 | 0.433 | 0.6440 | No |
| 43 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 4313 | 0.337 | 0.6319 | No |
| 44 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 4423 | 0.319 | 0.6317 | No |
| 45 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 4649 | 0.288 | 0.6282 | No |
| 46 | SPIB | Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242] | 5258 | 0.193 | 0.6135 | No |
| 47 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 5893 | 0.100 | 0.5972 | No |
| 48 | UNKL | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] | 6010 | 0.086 | 0.5949 | No |
| 49 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 6039 | 0.084 | 0.5948 | No |
| 50 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6767 | 0.000 | 0.5752 | No |
| 51 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 7522 | 0.000 | 0.5548 | No |
| 52 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9387 | 0.000 | 0.5043 | No |
| 53 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9978 | 0.000 | 0.4884 | No |
| 54 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 10167 | 0.000 | 0.4833 | No |
| 55 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 10234 | 0.000 | 0.4815 | No |
| 56 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 10239 | 0.000 | 0.4814 | No |
| 57 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10378 | 0.000 | 0.4777 | No |
| 58 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10850 | 0.000 | 0.4649 | No |
| 59 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 11351 | 0.000 | 0.4514 | No |
| 60 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12478 | 0.000 | 0.4209 | No |
| 61 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12671 | 0.000 | 0.4158 | No |
| 62 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12675 | 0.000 | 0.4157 | No |
| 63 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12704 | 0.000 | 0.4149 | No |
| 64 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12740 | 0.000 | 0.4140 | No |
| 65 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13301 | 0.000 | 0.3988 | No |
| 66 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 14055 | 0.000 | 0.3784 | No |
| 67 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14802 | 0.000 | 0.3583 | No |
| 68 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15750 | 0.000 | 0.3326 | No |
| 69 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15868 | 0.000 | 0.3295 | No |
| 70 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16284 | 0.000 | 0.3183 | No |
| 71 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16314 | 0.000 | 0.3175 | No |
| 72 | MST1L | macrophage stimulating 1 like [Source:HGNC Symbol;Acc:HGNC:7390] | 16353 | 0.000 | 0.3164 | No |
| 73 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16594 | 0.000 | 0.3099 | No |
| 74 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16605 | 0.000 | 0.3097 | No |
| 75 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17213 | 0.000 | 0.2933 | No |
| 76 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17819 | 0.000 | 0.2769 | No |
| 77 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18400 | 0.000 | 0.2612 | No |
| 78 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18419 | 0.000 | 0.2607 | No |
| 79 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18447 | 0.000 | 0.2600 | No |
| 80 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18847 | 0.000 | 0.2492 | No |
| 81 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18889 | 0.000 | 0.2481 | No |
| 82 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19427 | 0.000 | 0.2336 | No |
| 83 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20599 | 0.000 | 0.2019 | No |
| 84 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20793 | 0.000 | 0.1967 | No |
| 85 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22438 | 0.000 | 0.1522 | No |
| 86 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22920 | 0.000 | 0.1392 | No |
| 87 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 22980 | 0.000 | 0.1376 | No |
| 88 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 22997 | 0.000 | 0.1371 | No |
| 89 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 23008 | 0.000 | 0.1369 | No |
| 90 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 23434 | 0.000 | 0.1254 | No |
| 91 | UCP1 | uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517] | 23466 | 0.000 | 0.1245 | No |
| 92 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23552 | 0.000 | 0.1222 | No |
| 93 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 24388 | 0.000 | 0.0996 | No |
| 94 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 25069 | 0.000 | 0.0812 | No |
| 95 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 25077 | 0.000 | 0.0811 | No |
| 96 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 25556 | 0.000 | 0.0681 | No |
| 97 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25557 | 0.000 | 0.0681 | No |
| 98 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25824 | 0.000 | 0.0609 | No |
| 99 | SLC22A23 | solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106] | 26740 | 0.000 | 0.0362 | No |
| 100 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 27760 | -0.040 | 0.0090 | No |
| 101 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 27844 | -0.051 | 0.0072 | No |
| 102 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 28360 | -0.114 | -0.0057 | No |
| 103 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 28742 | -0.155 | -0.0147 | No |
| 104 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 28981 | -0.188 | -0.0195 | No |
| 105 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 29630 | -0.270 | -0.0346 | No |
| 106 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 29686 | -0.276 | -0.0336 | No |
| 107 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 30032 | -0.316 | -0.0402 | No |
| 108 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 30103 | -0.324 | -0.0392 | No |
| 109 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 30442 | -0.370 | -0.0450 | No |
| 110 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 30814 | -0.425 | -0.0513 | No |
| 111 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 30823 | -0.426 | -0.0477 | No |
| 112 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 30925 | -0.440 | -0.0465 | No |
| 113 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 31534 | -0.537 | -0.0582 | No |
| 114 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 31827 | -0.581 | -0.0610 | No |
| 115 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 32280 | -0.671 | -0.0672 | No |
| 116 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 32829 | -0.800 | -0.0750 | No |
| 117 | RUBCNL | rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420] | 34345 | -1.232 | -0.1050 | No |
| 118 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 34633 | -1.342 | -0.1009 | No |
| 119 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 34714 | -1.382 | -0.0908 | No |
| 120 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 34931 | -1.484 | -0.0834 | No |
| 121 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 35690 | -1.920 | -0.0869 | No |
| 122 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 35984 | -2.141 | -0.0758 | No |
| 123 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36138 | -2.271 | -0.0598 | No |
| 124 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 36469 | -2.640 | -0.0453 | No |
| 125 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36871 | -3.359 | -0.0263 | No |
| 126 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36945 | -3.630 | 0.0039 | No |
