Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GOBP_ACUTE_PHASE_RESPONSE |
| Enrichment Score (ES) | 0.8507989 |
| Normalized Enrichment Score (NES) | 1.9246694 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0037236952 |
| FWER p-Value | 0.019 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.925 | 0.1502 | Yes |
| 2 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 2 | 4.920 | 0.3003 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 3 | 4.907 | 0.4500 | Yes |
| 4 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 17 | 4.706 | 0.5932 | Yes |
| 5 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 40 | 4.264 | 0.7226 | Yes |
| 6 | ASS1 | argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758] | 419 | 2.300 | 0.7826 | Yes |
| 7 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 864 | 1.555 | 0.8180 | Yes |
| 8 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1150 | 1.327 | 0.8508 | Yes |
| 9 | SAA2 | serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514] | 3737 | 0.434 | 0.7942 | No |
| 10 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 4499 | 0.309 | 0.7831 | No |
| 11 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4730 | 0.275 | 0.7853 | No |
| 12 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 4880 | 0.250 | 0.7889 | No |
| 13 | HP | haptoglobin [Source:HGNC Symbol;Acc:HGNC:5141] | 4900 | 0.246 | 0.7959 | No |
| 14 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4960 | 0.237 | 0.8015 | No |
| 15 | SERPINF2 | serpin family F member 2 [Source:HGNC Symbol;Acc:HGNC:9075] | 5163 | 0.207 | 0.8024 | No |
| 16 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 5324 | 0.182 | 0.8036 | No |
| 17 | APCS | amyloid P component, serum [Source:HGNC Symbol;Acc:HGNC:584] | 7040 | 0.000 | 0.7573 | No |
| 18 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 8091 | 0.000 | 0.7290 | No |
| 19 | APOL2 | apolipoprotein L2 [Source:HGNC Symbol;Acc:HGNC:619] | 10379 | 0.000 | 0.6673 | No |
| 20 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12557 | 0.000 | 0.6085 | No |
| 21 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12676 | 0.000 | 0.6053 | No |
| 22 | IL22 | interleukin 22 [Source:HGNC Symbol;Acc:HGNC:14900] | 13964 | 0.000 | 0.5706 | No |
| 23 | MBL2 | mannose binding lectin 2 [Source:HGNC Symbol;Acc:HGNC:6922] | 15729 | 0.000 | 0.5229 | No |
| 24 | CRP | C-reactive protein [Source:HGNC Symbol;Acc:HGNC:2367] | 15981 | 0.000 | 0.5162 | No |
| 25 | F2 | coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535] | 16252 | 0.000 | 0.5089 | No |
| 26 | EPO | erythropoietin [Source:HGNC Symbol;Acc:HGNC:3415] | 16561 | 0.000 | 0.5006 | No |
| 27 | HFE | homeostatic iron regulator [Source:HGNC Symbol;Acc:HGNC:4886] | 17380 | 0.000 | 0.4785 | No |
| 28 | INS | insulin [Source:HGNC Symbol;Acc:HGNC:6081] | 17779 | 0.000 | 0.4677 | No |
| 29 | SERPINA1 | serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941] | 17812 | 0.000 | 0.4669 | No |
| 30 | LBP | lipopolysaccharide binding protein [Source:HGNC Symbol;Acc:HGNC:6517] | 18502 | 0.000 | 0.4483 | No |
| 31 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18636 | 0.000 | 0.4447 | No |
| 32 | ORM2 | orosomucoid 2 [Source:HGNC Symbol;Acc:HGNC:8499] | 18637 | 0.000 | 0.4447 | No |
| 33 | MRGPRX1 | MAS related GPR family member X1 [Source:HGNC Symbol;Acc:HGNC:17962] | 19452 | 0.000 | 0.4227 | No |
| 34 | PTGER3 | prostaglandin E receptor 3 [Source:HGNC Symbol;Acc:HGNC:9595] | 20086 | 0.000 | 0.4056 | No |
| 35 | TFR2 | transferrin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11762] | 20805 | 0.000 | 0.3862 | No |
| 36 | EDNRB | endothelin receptor type B [Source:HGNC Symbol;Acc:HGNC:3180] | 21902 | 0.000 | 0.3567 | No |
| 37 | AHSG | alpha 2-HS glycoprotein [Source:HGNC Symbol;Acc:HGNC:349] | 23183 | 0.000 | 0.3221 | No |
| 38 | SAA4 | serum amyloid A4, constitutive [Source:HGNC Symbol;Acc:HGNC:10516] | 24729 | 0.000 | 0.2804 | No |
| 39 | HAMP | hepcidin antimicrobial peptide [Source:HGNC Symbol;Acc:HGNC:15598] | 24904 | 0.000 | 0.2757 | No |
| 40 | REG3A | regenerating family member 3 alpha [Source:HGNC Symbol;Acc:HGNC:8601] | 26404 | 0.000 | 0.2352 | No |
| 41 | REG3G | regenerating family member 3 gamma [Source:HGNC Symbol;Acc:HGNC:29595] | 26408 | 0.000 | 0.2352 | No |
| 42 | UGT1A1 | UDP glucuronosyltransferase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:12530] | 26640 | 0.000 | 0.2289 | No |
| 43 | ITIH4 | inter-alpha-trypsin inhibitor heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:6169] | 26920 | 0.000 | 0.2214 | No |
| 44 | TNFRSF11A | TNF receptor superfamily member 11a [Source:HGNC Symbol;Acc:HGNC:11908] | 30148 | -0.331 | 0.1444 | No |
| 45 | F8 | coagulation factor VIII [Source:HGNC Symbol;Acc:HGNC:3546] | 31671 | -0.559 | 0.1203 | No |
| 46 | SIGIRR | single Ig and TIR domain containing [Source:HGNC Symbol;Acc:HGNC:30575] | 33028 | -0.850 | 0.1097 | No |
