Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_FATTY_ACID_BETA_OXIDATION |
| Enrichment Score (ES) | -0.7770261 |
| Normalized Enrichment Score (NES) | -1.6306669 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.066513404 |
| FWER p-Value | 0.348 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SESN2 | sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] | 693 | 1.772 | 0.0034 | No |
| 2 | MECR | mitochondrial trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:19691] | 1071 | 1.384 | 0.0106 | No |
| 3 | CPT1B | carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329] | 2669 | 0.672 | -0.0242 | No |
| 4 | PPARD | peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235] | 4436 | 0.317 | -0.0679 | No |
| 5 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 5197 | 0.201 | -0.0859 | No |
| 6 | AKT1 | AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391] | 5951 | 0.093 | -0.1051 | No |
| 7 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 6378 | 0.042 | -0.1161 | No |
| 8 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 8300 | 0.000 | -0.1680 | No |
| 9 | ADIPOQ | adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:HGNC:13633] | 8407 | 0.000 | -0.1708 | No |
| 10 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 11191 | 0.000 | -0.2460 | No |
| 11 | DECR1 | 2,4-dienoyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:2753] | 12441 | 0.000 | -0.2798 | No |
| 12 | ACOXL | acyl-CoA oxidase like [Source:HGNC Symbol;Acc:HGNC:25621] | 12544 | 0.000 | -0.2825 | No |
| 13 | ACOX2 | acyl-CoA oxidase 2 [Source:HGNC Symbol;Acc:HGNC:120] | 12549 | 0.000 | -0.2826 | No |
| 14 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12557 | 0.000 | -0.2828 | No |
| 15 | PLIN5 | perilipin 5 [Source:HGNC Symbol;Acc:HGNC:33196] | 15918 | 0.000 | -0.3736 | No |
| 16 | TWIST1 | twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428] | 17282 | 0.000 | -0.4104 | No |
| 17 | LEP | leptin [Source:HGNC Symbol;Acc:HGNC:6553] | 18525 | 0.000 | -0.4440 | No |
| 18 | IRS1 | insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125] | 21803 | 0.000 | -0.5325 | No |
| 19 | IRS2 | insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126] | 21806 | 0.000 | -0.5326 | No |
| 20 | PPARA | peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232] | 24102 | 0.000 | -0.5946 | No |
| 21 | FABP1 | fatty acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3555] | 26856 | 0.000 | -0.6689 | No |
| 22 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 27657 | -0.028 | -0.6902 | No |
| 23 | ACADVL | acyl-CoA dehydrogenase very long chain [Source:HGNC Symbol;Acc:HGNC:92] | 27750 | -0.039 | -0.6922 | No |
| 24 | MFSD2A | major facilitator superfamily domain containing 2A [Source:HGNC Symbol;Acc:HGNC:25897] | 27759 | -0.040 | -0.6919 | No |
| 25 | AKT2 | AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392] | 27894 | -0.059 | -0.6948 | No |
| 26 | GCDH | glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189] | 28090 | -0.079 | -0.6991 | No |
| 27 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 29187 | -0.211 | -0.7260 | No |
| 28 | ETFA | electron transfer flavoprotein subunit alpha [Source:HGNC Symbol;Acc:HGNC:3481] | 29499 | -0.252 | -0.7313 | No |
| 29 | BDH2 | 3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389] | 29827 | -0.291 | -0.7365 | No |
| 30 | ETFB | electron transfer flavoprotein subunit beta [Source:HGNC Symbol;Acc:HGNC:3482] | 30296 | -0.350 | -0.7447 | No |
| 31 | AMACR | alpha-methylacyl-CoA racemase [Source:HGNC Symbol;Acc:HGNC:451] | 30839 | -0.429 | -0.7540 | No |
| 32 | ECHDC2 | enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408] | 30997 | -0.453 | -0.7526 | No |
| 33 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 31699 | -0.564 | -0.7645 | No |
| 34 | ECHDC1 | ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489] | 32156 | -0.643 | -0.7688 | Yes |
| 35 | ECI1 | enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703] | 32463 | -0.715 | -0.7681 | Yes |
| 36 | HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801] | 32465 | -0.715 | -0.7592 | Yes |
| 37 | CPT1C | carnitine palmitoyltransferase 1C [Source:HGNC Symbol;Acc:HGNC:18540] | 32674 | -0.762 | -0.7553 | Yes |
| 38 | DECR2 | 2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754] | 32710 | -0.771 | -0.7466 | Yes |
| 39 | PEX7 | peroxisomal biogenesis factor 7 [Source:HGNC Symbol;Acc:HGNC:8860] | 32882 | -0.811 | -0.7410 | Yes |
| 40 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 33254 | -0.909 | -0.7397 | Yes |
| 41 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 33393 | -0.948 | -0.7316 | Yes |
| 42 | ACACB | acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85] | 33410 | -0.951 | -0.7201 | Yes |
| 43 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 33522 | -0.979 | -0.7108 | Yes |
| 44 | TYSND1 | trypsin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28531] | 33741 | -1.042 | -0.7037 | Yes |
| 45 | IVD | isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186] | 33784 | -1.050 | -0.6917 | Yes |
| 46 | ACAD11 | acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211] | 34040 | -1.128 | -0.6845 | Yes |
| 47 | ACAD10 | acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597] | 34074 | -1.137 | -0.6712 | Yes |
| 48 | ETFDH | electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483] | 34085 | -1.141 | -0.6572 | Yes |
| 49 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 34093 | -1.143 | -0.6430 | Yes |
| 50 | MCAT | malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622] | 34157 | -1.163 | -0.6302 | Yes |
| 51 | HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [Source:HGNC Symbol;Acc:HGNC:4803] | 34223 | -1.189 | -0.6171 | Yes |
| 52 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 34395 | -1.250 | -0.6061 | Yes |
| 53 | ECHS1 | enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151] | 34639 | -1.344 | -0.5958 | Yes |
| 54 | ACAT1 | acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93] | 34700 | -1.375 | -0.5802 | Yes |
| 55 | CPT2 | carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:2330] | 35034 | -1.535 | -0.5700 | Yes |
| 56 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 35205 | -1.627 | -0.5543 | Yes |
| 57 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35242 | -1.647 | -0.5347 | Yes |
| 58 | ACAA2 | acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] | 35312 | -1.681 | -0.5155 | Yes |
| 59 | ACADL | acyl-CoA dehydrogenase long chain [Source:HGNC Symbol;Acc:HGNC:88] | 35421 | -1.744 | -0.4966 | Yes |
| 60 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 35473 | -1.778 | -0.4757 | Yes |
| 61 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35615 | -1.861 | -0.4563 | Yes |
| 62 | ABCD4 | ATP binding cassette subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:68] | 35801 | -2.000 | -0.4362 | Yes |
| 63 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 35837 | -2.026 | -0.4119 | Yes |
| 64 | HSD17B10 | hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800] | 36257 | -2.393 | -0.3932 | Yes |
| 65 | ACAT2 | acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] | 36271 | -2.402 | -0.3636 | Yes |
| 66 | ACADS | acyl-CoA dehydrogenase short chain [Source:HGNC Symbol;Acc:HGNC:90] | 36317 | -2.438 | -0.3343 | Yes |
| 67 | ACADM | acyl-CoA dehydrogenase medium chain [Source:HGNC Symbol;Acc:HGNC:89] | 36324 | -2.449 | -0.3038 | Yes |
| 68 | AUH | AU RNA binding methylglutaconyl-CoA hydratase [Source:HGNC Symbol;Acc:HGNC:890] | 36376 | -2.509 | -0.2738 | Yes |
| 69 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 36407 | -2.554 | -0.2427 | Yes |
| 70 | CPT1A | carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328] | 36525 | -2.722 | -0.2118 | Yes |
| 71 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36596 | -2.823 | -0.1784 | Yes |
| 72 | CROT | carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366] | 36775 | -3.146 | -0.1438 | Yes |
| 73 | HADH | hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799] | 36927 | -3.577 | -0.1032 | Yes |
| 74 | ETFBKMT | electron transfer flavoprotein subunit beta lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:28739] | 36981 | -3.781 | -0.0573 | Yes |
| 75 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37086 | -4.814 | 0.0001 | Yes |
