Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_FATTY_ACID_CATABOLIC_PROCESS |
| Enrichment Score (ES) | -0.7478146 |
| Normalized Enrichment Score (NES) | -1.5992427 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07479829 |
| FWER p-Value | 0.717 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HAO1 | hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809] | 362 | 2.443 | 0.0117 | No |
| 2 | SESN2 | sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] | 693 | 1.772 | 0.0183 | No |
| 3 | MECR | mitochondrial trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:19691] | 1071 | 1.384 | 0.0203 | No |
| 4 | AIG1 | androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:21607] | 1623 | 1.056 | 0.0147 | No |
| 5 | CPT1B | carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329] | 2669 | 0.672 | -0.0076 | No |
| 6 | MMAA | metabolism of cobalamin associated A [Source:HGNC Symbol;Acc:HGNC:18871] | 3137 | 0.560 | -0.0154 | No |
| 7 | PPARD | peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235] | 4436 | 0.317 | -0.0477 | No |
| 8 | ALDH3A2 | aldehyde dehydrogenase 3 family member A2 [Source:HGNC Symbol;Acc:HGNC:403] | 4477 | 0.313 | -0.0460 | No |
| 9 | ABHD2 | abhydrolase domain containing 2, acylglycerol lipase [Source:HGNC Symbol;Acc:HGNC:18717] | 4678 | 0.284 | -0.0489 | No |
| 10 | PCK1 | phosphoenolpyruvate carboxykinase 1 [Source:HGNC Symbol;Acc:HGNC:8724] | 4769 | 0.269 | -0.0490 | No |
| 11 | ABHD1 | abhydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17553] | 4965 | 0.237 | -0.0522 | No |
| 12 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 5197 | 0.201 | -0.0566 | No |
| 13 | AKT1 | AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391] | 5951 | 0.093 | -0.0762 | No |
| 14 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 6064 | 0.081 | -0.0785 | No |
| 15 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 6378 | 0.042 | -0.0866 | No |
| 16 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 8300 | 0.000 | -0.1385 | No |
| 17 | ADIPOQ | adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:HGNC:13633] | 8407 | 0.000 | -0.1414 | No |
| 18 | NUDT7 | nudix hydrolase 7 [Source:HGNC Symbol;Acc:HGNC:8054] | 8517 | 0.000 | -0.1443 | No |
| 19 | GLYATL2 | glycine-N-acyltransferase like 2 [Source:HGNC Symbol;Acc:HGNC:24178] | 10630 | 0.000 | -0.2015 | No |
| 20 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 11191 | 0.000 | -0.2166 | No |
| 21 | DECR1 | 2,4-dienoyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:2753] | 12441 | 0.000 | -0.2504 | No |
| 22 | ACOXL | acyl-CoA oxidase like [Source:HGNC Symbol;Acc:HGNC:25621] | 12544 | 0.000 | -0.2531 | No |
| 23 | ACOX2 | acyl-CoA oxidase 2 [Source:HGNC Symbol;Acc:HGNC:120] | 12549 | 0.000 | -0.2532 | No |
| 24 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12557 | 0.000 | -0.2534 | No |
| 25 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15883 | 0.000 | -0.3433 | No |
| 26 | PLIN5 | perilipin 5 [Source:HGNC Symbol;Acc:HGNC:33196] | 15918 | 0.000 | -0.3442 | No |
| 27 | TWIST1 | twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428] | 17282 | 0.000 | -0.3811 | No |
| 28 | ADTRP | androgen dependent TFPI regulating protein [Source:HGNC Symbol;Acc:HGNC:21214] | 18470 | 0.000 | -0.4132 | No |
| 29 | LEP | leptin [Source:HGNC Symbol;Acc:HGNC:6553] | 18525 | 0.000 | -0.4146 | No |
| 30 | IRS1 | insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125] | 21803 | 0.000 | -0.5033 | No |
| 31 | IRS2 | insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126] | 21806 | 0.000 | -0.5033 | No |
| 32 | PPARA | peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232] | 24102 | 0.000 | -0.5654 | No |
| 33 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 24895 | 0.000 | -0.5868 | No |
| 34 | FABP1 | fatty acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3555] | 26856 | 0.000 | -0.6398 | No |
| 35 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 27657 | -0.028 | -0.6611 | No |
| 36 | ACADVL | acyl-CoA dehydrogenase very long chain [Source:HGNC Symbol;Acc:HGNC:92] | 27750 | -0.039 | -0.6633 | No |
| 37 | MFSD2A | major facilitator superfamily domain containing 2A [Source:HGNC Symbol;Acc:HGNC:25897] | 27759 | -0.040 | -0.6632 | No |
| 38 | AKT2 | AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392] | 27894 | -0.059 | -0.6663 | No |
| 39 | GCDH | glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189] | 28090 | -0.079 | -0.6708 | No |
| 40 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 28788 | -0.161 | -0.6883 | No |
| 41 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 29187 | -0.211 | -0.6972 | No |
| 42 | ETFA | electron transfer flavoprotein subunit alpha [Source:HGNC Symbol;Acc:HGNC:3481] | 29499 | -0.252 | -0.7034 | No |
| 43 | PECR | peroxisomal trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:18281] | 29800 | -0.288 | -0.7089 | No |
| 44 | BDH2 | 3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389] | 29827 | -0.291 | -0.7071 | No |
| 45 | ABHD3 | abhydrolase domain containing 3, phospholipase [Source:HGNC Symbol;Acc:HGNC:18718] | 29871 | -0.295 | -0.7057 | No |
| 46 | ETFB | electron transfer flavoprotein subunit beta [Source:HGNC Symbol;Acc:HGNC:3482] | 30296 | -0.350 | -0.7140 | No |
| 47 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 30765 | -0.419 | -0.7230 | No |
| 48 | AMACR | alpha-methylacyl-CoA racemase [Source:HGNC Symbol;Acc:HGNC:451] | 30839 | -0.429 | -0.7212 | No |
| 49 | ECHDC2 | enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408] | 30997 | -0.453 | -0.7215 | No |
| 50 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 31699 | -0.564 | -0.7355 | No |
| 51 | ECHDC1 | ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489] | 32156 | -0.643 | -0.7422 | Yes |
| 52 | SLC27A4 | solute carrier family 27 member 4 [Source:HGNC Symbol;Acc:HGNC:10998] | 32206 | -0.654 | -0.7377 | Yes |
| 53 | ECI1 | enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703] | 32463 | -0.715 | -0.7384 | Yes |
| 54 | HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801] | 32465 | -0.715 | -0.7321 | Yes |
| 55 | CPT1C | carnitine palmitoyltransferase 1C [Source:HGNC Symbol;Acc:HGNC:18540] | 32674 | -0.762 | -0.7310 | Yes |
| 56 | DECR2 | 2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754] | 32710 | -0.771 | -0.7252 | Yes |
| 57 | PEX7 | peroxisomal biogenesis factor 7 [Source:HGNC Symbol;Acc:HGNC:8860] | 32882 | -0.811 | -0.7227 | Yes |
| 58 | ILVBL | ilvB acetolactate synthase like [Source:HGNC Symbol;Acc:HGNC:6041] | 33177 | -0.888 | -0.7228 | Yes |
| 59 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 33254 | -0.909 | -0.7169 | Yes |
| 60 | LPIN3 | lipin 3 [Source:HGNC Symbol;Acc:HGNC:14451] | 33299 | -0.923 | -0.7100 | Yes |
| 61 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 33393 | -0.948 | -0.7042 | Yes |
| 62 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33400 | -0.949 | -0.6960 | Yes |
| 63 | ACACB | acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85] | 33410 | -0.951 | -0.6879 | Yes |
| 64 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 33522 | -0.979 | -0.6823 | Yes |
| 65 | TYSND1 | trypsin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28531] | 33741 | -1.042 | -0.6790 | Yes |
| 66 | IVD | isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186] | 33784 | -1.050 | -0.6709 | Yes |
| 67 | ACAD11 | acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211] | 34040 | -1.128 | -0.6679 | Yes |
| 68 | PHYH | phytanoyl-CoA 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:8940] | 34062 | -1.133 | -0.6585 | Yes |
| 69 | ACAD10 | acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597] | 34074 | -1.137 | -0.6488 | Yes |
| 70 | ETFDH | electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483] | 34085 | -1.141 | -0.6390 | Yes |
| 71 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 34093 | -1.143 | -0.6292 | Yes |
| 72 | MCAT | malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622] | 34157 | -1.163 | -0.6207 | Yes |
| 73 | HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [Source:HGNC Symbol;Acc:HGNC:4803] | 34223 | -1.189 | -0.6120 | Yes |
| 74 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 34395 | -1.250 | -0.6056 | Yes |
| 75 | ECHS1 | enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151] | 34639 | -1.344 | -0.6003 | Yes |
| 76 | ACAT1 | acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93] | 34700 | -1.375 | -0.5899 | Yes |
| 77 | CPT2 | carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:2330] | 35034 | -1.535 | -0.5854 | Yes |
| 78 | FAAH | fatty acid amide hydrolase [Source:HGNC Symbol;Acc:HGNC:3553] | 35075 | -1.559 | -0.5728 | Yes |
| 79 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 35205 | -1.627 | -0.5620 | Yes |
| 80 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35242 | -1.647 | -0.5485 | Yes |
| 81 | ACAA2 | acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] | 35312 | -1.681 | -0.5355 | Yes |
| 82 | ACADL | acyl-CoA dehydrogenase long chain [Source:HGNC Symbol;Acc:HGNC:88] | 35421 | -1.744 | -0.5231 | Yes |
| 83 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 35473 | -1.778 | -0.5089 | Yes |
| 84 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35615 | -1.861 | -0.4963 | Yes |
| 85 | PCCA | propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653] | 35673 | -1.905 | -0.4811 | Yes |
| 86 | ABCD4 | ATP binding cassette subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:68] | 35801 | -2.000 | -0.4670 | Yes |
| 87 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 35837 | -2.026 | -0.4501 | Yes |
| 88 | ACBD5 | acyl-CoA binding domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23338] | 35892 | -2.077 | -0.4333 | Yes |
| 89 | MMUT | methylmalonyl-CoA mutase [Source:HGNC Symbol;Acc:HGNC:7526] | 35977 | -2.133 | -0.4169 | Yes |
| 90 | PLA2G15 | phospholipase A2 group XV [Source:HGNC Symbol;Acc:HGNC:17163] | 36184 | -2.315 | -0.4021 | Yes |
| 91 | HSD17B10 | hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800] | 36257 | -2.393 | -0.3830 | Yes |
| 92 | ACAT2 | acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] | 36271 | -2.402 | -0.3622 | Yes |
| 93 | MCEE | methylmalonyl-CoA epimerase [Source:HGNC Symbol;Acc:HGNC:16732] | 36272 | -2.403 | -0.3411 | Yes |
| 94 | ACADS | acyl-CoA dehydrogenase short chain [Source:HGNC Symbol;Acc:HGNC:90] | 36317 | -2.438 | -0.3209 | Yes |
| 95 | ACADM | acyl-CoA dehydrogenase medium chain [Source:HGNC Symbol;Acc:HGNC:89] | 36324 | -2.449 | -0.2995 | Yes |
| 96 | AUH | AU RNA binding methylglutaconyl-CoA hydratase [Source:HGNC Symbol;Acc:HGNC:890] | 36376 | -2.509 | -0.2788 | Yes |
| 97 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 36407 | -2.554 | -0.2572 | Yes |
| 98 | CPT1A | carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328] | 36525 | -2.722 | -0.2364 | Yes |
| 99 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36596 | -2.823 | -0.2135 | Yes |
| 100 | LPIN2 | lipin 2 [Source:HGNC Symbol;Acc:HGNC:14450] | 36598 | -2.824 | -0.1887 | Yes |
| 101 | CROT | carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366] | 36775 | -3.146 | -0.1658 | Yes |
| 102 | HADH | hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799] | 36927 | -3.577 | -0.1384 | Yes |
| 103 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 36952 | -3.659 | -0.1069 | Yes |
| 104 | ETFBKMT | electron transfer flavoprotein subunit beta lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:28739] | 36981 | -3.781 | -0.0744 | Yes |
| 105 | HACL1 | 2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856] | 37021 | -3.983 | -0.0405 | Yes |
| 106 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37086 | -4.814 | 0.0001 | Yes |
