Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_MALE_MEIOTIC_NUCLEAR_DIVISION |
| Enrichment Score (ES) | -0.83583283 |
| Normalized Enrichment Score (NES) | -1.6180936 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.060272023 |
| FWER p-Value | 0.479 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SYCP2 | synaptonemal complex protein 2 [Source:HGNC Symbol;Acc:HGNC:11490] | 4687 | 0.282 | -0.1190 | No |
| 2 | HSF2BP | heat shock transcription factor 2 binding protein [Source:HGNC Symbol;Acc:HGNC:5226] | 5100 | 0.216 | -0.1244 | No |
| 3 | UBR2 | ubiquitin protein ligase E3 component n-recognin 2 [Source:HGNC Symbol;Acc:HGNC:21289] | 6605 | 0.013 | -0.1646 | No |
| 4 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7918 | 0.000 | -0.2001 | No |
| 5 | ASZ1 | ankyrin repeat, SAM and basic leucine zipper domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1350] | 8231 | 0.000 | -0.2085 | No |
| 6 | CATSPERZ | catsper channel auxiliary subunit zeta [Source:HGNC Symbol;Acc:HGNC:19231] | 8668 | 0.000 | -0.2203 | No |
| 7 | TDRD9 | tudor domain containing 9 [Source:HGNC Symbol;Acc:HGNC:20122] | 9419 | 0.000 | -0.2405 | No |
| 8 | MOV10L1 | Mov10 like RISC complex RNA helicase 1 [Source:HGNC Symbol;Acc:HGNC:7201] | 9485 | 0.000 | -0.2423 | No |
| 9 | BTBD18 | BTB domain containing 18 [Source:HGNC Symbol;Acc:HGNC:37214] | 9488 | 0.000 | -0.2423 | No |
| 10 | DNMT3L | DNA methyltransferase 3 like [Source:HGNC Symbol;Acc:HGNC:2980] | 10967 | 0.000 | -0.2822 | No |
| 11 | MEIOC | meiosis specific with coiled-coil domain [Source:HGNC Symbol;Acc:HGNC:26670] | 11055 | 0.000 | -0.2846 | No |
| 12 | MEIKIN | meiotic kinetochore factor [Source:HGNC Symbol;Acc:HGNC:51253] | 13068 | 0.000 | -0.3389 | No |
| 13 | REC8 | REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879] | 13896 | 0.000 | -0.3612 | No |
| 14 | TEX11 | testis expressed 11 [Source:HGNC Symbol;Acc:HGNC:11733] | 15398 | 0.000 | -0.4017 | No |
| 15 | TEX15 | testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738] | 15400 | 0.000 | -0.4017 | No |
| 16 | TEX19 | testis expressed 19 [Source:HGNC Symbol;Acc:HGNC:33802] | 15403 | 0.000 | -0.4018 | No |
| 17 | TDRD12 | tudor domain containing 12 [Source:HGNC Symbol;Acc:HGNC:25044] | 16588 | 0.000 | -0.4338 | No |
| 18 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16961 | 0.000 | -0.4438 | No |
| 19 | SPO11 | SPO11 initiator of meiotic double stranded breaks [Source:HGNC Symbol;Acc:HGNC:11250] | 19432 | 0.000 | -0.5105 | No |
| 20 | MAEL | maelstrom spermatogenic transposon silencer [Source:HGNC Symbol;Acc:HGNC:25929] | 27168 | 0.000 | -0.7193 | No |
| 21 | UBB | ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] | 27590 | -0.019 | -0.7301 | No |
| 22 | SYCP3 | synaptonemal complex protein 3 [Source:HGNC Symbol;Acc:HGNC:18130] | 27729 | -0.037 | -0.7329 | No |
| 23 | CYP26B1 | cytochrome P450 family 26 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:20581] | 28085 | -0.078 | -0.7404 | No |
| 24 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 28769 | -0.159 | -0.7546 | No |
| 25 | SPDYA | speedy/RINGO cell cycle regulator family member A [Source:HGNC Symbol;Acc:HGNC:30613] | 29425 | -0.241 | -0.7659 | No |
| 26 | TEX14 | testis expressed 14, intercellular bridge forming factor [Source:HGNC Symbol;Acc:HGNC:11737] | 29756 | -0.283 | -0.7673 | No |
| 27 | DDX4 | DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700] | 30337 | -0.355 | -0.7735 | No |
| 28 | TDRKH | tudor and KH domain containing [Source:HGNC Symbol;Acc:HGNC:11713] | 31611 | -0.551 | -0.7932 | No |
| 29 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 33190 | -0.890 | -0.8122 | Yes |
| 30 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 33264 | -0.912 | -0.7899 | Yes |
| 31 | MEIOB | meiosis specific with OB-fold [Source:HGNC Symbol;Acc:HGNC:28569] | 33279 | -0.917 | -0.7660 | Yes |
| 32 | TAF1L | TATA-box binding protein associated factor 1 like [Source:HGNC Symbol;Acc:HGNC:18056] | 33823 | -1.061 | -0.7524 | Yes |
| 33 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 33866 | -1.073 | -0.7251 | Yes |
| 34 | KIF18A | kinesin family member 18A [Source:HGNC Symbol;Acc:HGNC:29441] | 35217 | -1.634 | -0.7181 | Yes |
| 35 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 35234 | -1.641 | -0.6749 | Yes |
| 36 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 35350 | -1.702 | -0.6329 | Yes |
| 37 | M1AP | meiosis 1 associated protein [Source:HGNC Symbol;Acc:HGNC:25183] | 35368 | -1.714 | -0.5878 | Yes |
| 38 | MYBL1 | MYB proto-oncogene like 1 [Source:HGNC Symbol;Acc:HGNC:7547] | 35743 | -1.958 | -0.5459 | Yes |
| 39 | MLH3 | mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128] | 35913 | -2.094 | -0.4948 | Yes |
| 40 | FIGNL1 | fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286] | 35979 | -2.135 | -0.4399 | Yes |
| 41 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 36081 | -2.221 | -0.3836 | Yes |
| 42 | ING2 | inhibitor of growth family member 2 [Source:HGNC Symbol;Acc:HGNC:6063] | 36116 | -2.257 | -0.3246 | Yes |
| 43 | ATM | ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795] | 36325 | -2.450 | -0.2651 | Yes |
| 44 | AGO4 | argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424] | 36452 | -2.629 | -0.1987 | Yes |
| 45 | SHCBP1L | SHC binding and spindle associated 1 like [Source:HGNC Symbol;Acc:HGNC:16788] | 36983 | -3.784 | -0.1125 | Yes |
| 46 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 37069 | -4.345 | 0.0006 | Yes |
