Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_SEROTONIN_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.85537297 |
| Normalized Enrichment Score (NES) | -1.6029029 |
| Nominal p-value | 0.0013192613 |
| FDR q-value | 0.07194452 |
| FWER p-Value | 0.674 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 5974 | 0.090 | -0.1418 | No |
| 2 | OR6T1 | olfactory receptor family 6 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:14848] | 14560 | 0.000 | -0.3735 | No |
| 3 | OR5T3 | olfactory receptor family 5 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:15297] | 15009 | 0.000 | -0.3856 | No |
| 4 | OR5T2 | olfactory receptor family 5 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:15296] | 15011 | 0.000 | -0.3856 | No |
| 5 | HTR4 | 5-hydroxytryptamine receptor 4 [Source:HGNC Symbol;Acc:HGNC:5299] | 15652 | 0.000 | -0.4029 | No |
| 6 | HTR6 | 5-hydroxytryptamine receptor 6 [Source:HGNC Symbol;Acc:HGNC:5301] | 15654 | 0.000 | -0.4029 | No |
| 7 | HTR7 | 5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302] | 15655 | 0.000 | -0.4029 | No |
| 8 | HTR1E | 5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291] | 15716 | 0.000 | -0.4045 | No |
| 9 | HTR1F | 5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292] | 15718 | 0.000 | -0.4046 | No |
| 10 | HTR1D | 5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289] | 15719 | 0.000 | -0.4046 | No |
| 11 | HTR1A | 5-hydroxytryptamine receptor 1A [Source:HGNC Symbol;Acc:HGNC:5286] | 15720 | 0.000 | -0.4046 | No |
| 12 | HTR2B | 5-hydroxytryptamine receptor 2B [Source:HGNC Symbol;Acc:HGNC:5294] | 15726 | 0.000 | -0.4047 | No |
| 13 | HTR2C | 5-hydroxytryptamine receptor 2C [Source:HGNC Symbol;Acc:HGNC:5295] | 15727 | 0.000 | -0.4047 | No |
| 14 | HTR3E | 5-hydroxytryptamine receptor 3E [Source:HGNC Symbol;Acc:HGNC:24005] | 15731 | 0.000 | -0.4048 | No |
| 15 | HTR3C | 5-hydroxytryptamine receptor 3C [Source:HGNC Symbol;Acc:HGNC:24003] | 15732 | 0.000 | -0.4048 | No |
| 16 | HTR3D | 5-hydroxytryptamine receptor 3D [Source:HGNC Symbol;Acc:HGNC:24004] | 15733 | 0.000 | -0.4048 | No |
| 17 | HTR3A | 5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297] | 15734 | 0.000 | -0.4048 | No |
| 18 | HTR3B | 5-hydroxytryptamine receptor 3B [Source:HGNC Symbol;Acc:HGNC:5298] | 15735 | 0.000 | -0.4048 | No |
| 19 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15746 | 0.000 | -0.4050 | No |
| 20 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17848 | 0.000 | -0.4617 | No |
| 21 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17850 | 0.000 | -0.4618 | No |
| 22 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18486 | 0.000 | -0.4789 | No |
| 23 | OR10J5 | olfactory receptor family 10 subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:14993] | 25767 | 0.000 | -0.6754 | No |
| 24 | OR10H1 | olfactory receptor family 10 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8172] | 25790 | 0.000 | -0.6760 | No |
| 25 | OR10H3 | olfactory receptor family 10 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:8174] | 25791 | 0.000 | -0.6760 | No |
| 26 | OR10H2 | olfactory receptor family 10 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:8173] | 25792 | 0.000 | -0.6760 | No |
| 27 | OR10H5 | olfactory receptor family 10 subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:15389] | 25793 | 0.000 | -0.6760 | No |
| 28 | OR10H4 | olfactory receptor family 10 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15388] | 25794 | 0.000 | -0.6760 | No |
| 29 | OR11H4 | olfactory receptor family 11 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15347] | 26013 | 0.000 | -0.6819 | No |
| 30 | OR11H7 | olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15350] | 26022 | 0.000 | -0.6821 | No |
| 31 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 26776 | 0.000 | -0.7024 | No |
| 32 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 26779 | 0.000 | -0.7025 | No |
| 33 | HRH2 | histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183] | 26781 | 0.000 | -0.7025 | No |
| 34 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 26784 | 0.000 | -0.7025 | No |
| 35 | OR10J6P | olfactory receptor family 10 subfamily J member 6 pseudogene [Source:HGNC Symbol;Acc:HGNC:14994] | 27074 | 0.000 | -0.7103 | No |
| 36 | HTR2A | 5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293] | 27999 | -0.068 | -0.7207 | Yes |
| 37 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 28245 | -0.101 | -0.7055 | Yes |
| 38 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 30682 | -0.404 | -0.6843 | Yes |
| 39 | HTR1B | 5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287] | 37020 | -3.981 | 0.0019 | Yes |
