Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GOCC_PRERIBOSOME |
| Enrichment Score (ES) | 0.7985249 |
| Normalized Enrichment Score (NES) | 1.9572351 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0019630312 |
| FWER p-Value | 0.009 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 353 | 2.469 | 0.0234 | Yes |
| 2 | RIOK3 | RIO kinase 3 [Source:HGNC Symbol;Acc:HGNC:11451] | 375 | 2.425 | 0.0552 | Yes |
| 3 | RIOK2 | RIO kinase 2 [Source:HGNC Symbol;Acc:HGNC:18999] | 391 | 2.385 | 0.0867 | Yes |
| 4 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 401 | 2.357 | 0.1179 | Yes |
| 5 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 529 | 2.034 | 0.1416 | Yes |
| 6 | TSR1 | TSR1 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542] | 556 | 1.990 | 0.1675 | Yes |
| 7 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 559 | 1.986 | 0.1940 | Yes |
| 8 | UTP25 | UTP25 small subunit processor component [Source:HGNC Symbol;Acc:HGNC:28440] | 564 | 1.980 | 0.2203 | Yes |
| 9 | UTP23 | UTP23 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:28224] | 612 | 1.899 | 0.2444 | Yes |
| 10 | NOP58 | NOP58 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:29926] | 662 | 1.807 | 0.2672 | Yes |
| 11 | MDN1 | midasin AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:18302] | 699 | 1.766 | 0.2898 | Yes |
| 12 | NOL10 | nucleolar protein 10 [Source:HGNC Symbol;Acc:HGNC:25862] | 746 | 1.691 | 0.3112 | Yes |
| 13 | FTSJ3 | FtsJ RNA 2'-O-methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:17136] | 789 | 1.639 | 0.3319 | Yes |
| 14 | EIF6 | eukaryotic translation initiation factor 6 [Source:HGNC Symbol;Acc:HGNC:6159] | 834 | 1.586 | 0.3519 | Yes |
| 15 | WDR46 | WD repeat domain 46 [Source:HGNC Symbol;Acc:HGNC:13923] | 842 | 1.576 | 0.3727 | Yes |
| 16 | UTP4 | UTP4 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:1983] | 898 | 1.528 | 0.3917 | Yes |
| 17 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 900 | 1.527 | 0.4120 | Yes |
| 18 | EBNA1BP2 | EBNA1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15531] | 927 | 1.498 | 0.4313 | Yes |
| 19 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 950 | 1.477 | 0.4505 | Yes |
| 20 | BMS1 | BMS1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:23505] | 1155 | 1.323 | 0.4626 | Yes |
| 21 | FP565260.1 | periodic tryptophan protein 2 homolog [Source:NCBI gene (formerly Entrezgene);Acc:102724159] | 1161 | 1.317 | 0.4801 | Yes |
| 22 | HEATR1 | HEAT repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25517] | 1204 | 1.284 | 0.4961 | Yes |
| 23 | LTV1 | LTV1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:21173] | 1248 | 1.256 | 0.5117 | Yes |
| 24 | RRS1 | ribosome biogenesis regulator 1 homolog [Source:HGNC Symbol;Acc:HGNC:17083] | 1383 | 1.163 | 0.5236 | Yes |
| 25 | NOL6 | nucleolar protein 6 [Source:HGNC Symbol;Acc:HGNC:19910] | 1440 | 1.133 | 0.5372 | Yes |
| 26 | PDCD11 | programmed cell death 11 [Source:HGNC Symbol;Acc:HGNC:13408] | 1445 | 1.128 | 0.5522 | Yes |
| 27 | WDR12 | WD repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:14098] | 1453 | 1.125 | 0.5670 | Yes |
| 28 | SNU13 | small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819] | 1501 | 1.104 | 0.5805 | Yes |
| 29 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 1516 | 1.100 | 0.5948 | Yes |
| 30 | WDR37 | WD repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:31406] | 1646 | 1.049 | 0.6053 | Yes |
| 31 | SRFBP1 | serum response factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26333] | 1717 | 1.017 | 0.6170 | Yes |
| 32 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 1736 | 1.010 | 0.6300 | Yes |
| 33 | PWP2 | PWP2 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:9711] | 1792 | 0.991 | 0.6418 | Yes |
| 34 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 1838 | 0.969 | 0.6535 | Yes |
| 35 | NOP14 | NOP14 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:16821] | 2036 | 0.886 | 0.6600 | Yes |
| 36 | MAK16 | MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703] | 2136 | 0.840 | 0.6685 | Yes |
| 37 | EMG1 | EMG1 N1-specific pseudouridine methyltransferase [Source:HGNC Symbol;Acc:HGNC:16912] | 2145 | 0.837 | 0.6795 | Yes |
| 38 | FBLL1 | fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35458] | 2289 | 0.789 | 0.6862 | Yes |
| 39 | KRI1 | KRI1 homolog [Source:HGNC Symbol;Acc:HGNC:25769] | 2292 | 0.789 | 0.6967 | Yes |
| 40 | BOP1 | BOP1 ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:15519] | 2302 | 0.786 | 0.7069 | Yes |
| 41 | TBL3 | transducin beta like 3 [Source:HGNC Symbol;Acc:HGNC:11587] | 2357 | 0.767 | 0.7157 | Yes |
| 42 | FCF1 | FCF1 rRNA-processing protein [Source:HGNC Symbol;Acc:HGNC:20220] | 2499 | 0.725 | 0.7215 | Yes |
| 43 | RPF1 | ribosome production factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:30350] | 2622 | 0.688 | 0.7274 | Yes |
| 44 | FBL | fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599] | 2662 | 0.676 | 0.7354 | Yes |
| 45 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 2685 | 0.666 | 0.7437 | Yes |
| 46 | UTP6 | UTP6 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:18279] | 2777 | 0.645 | 0.7499 | Yes |
| 47 | WDR3 | WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12755] | 2929 | 0.605 | 0.7539 | Yes |
| 48 | RRP7A | ribosomal RNA processing 7 homolog A [Source:HGNC Symbol;Acc:HGNC:24286] | 3021 | 0.584 | 0.7592 | Yes |
| 49 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 3036 | 0.581 | 0.7666 | Yes |
| 50 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 3162 | 0.553 | 0.7706 | Yes |
| 51 | UTP18 | UTP18 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24274] | 3276 | 0.527 | 0.7746 | Yes |
| 52 | RIOK1 | RIO kinase 1 [Source:HGNC Symbol;Acc:HGNC:18656] | 3285 | 0.526 | 0.7814 | Yes |
| 53 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 3328 | 0.516 | 0.7871 | Yes |
| 54 | KRR1 | KRR1 small subunit processome component homolog [Source:HGNC Symbol;Acc:HGNC:5176] | 3422 | 0.496 | 0.7912 | Yes |
| 55 | RSL1D1 | ribosomal L1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24534] | 3478 | 0.484 | 0.7962 | Yes |
| 56 | XRCC5 | X-ray repair cross complementing 5 [Source:HGNC Symbol;Acc:HGNC:12833] | 3619 | 0.456 | 0.7985 | Yes |
| 57 | RRP36 | ribosomal RNA processing 36 [Source:HGNC Symbol;Acc:HGNC:21374] | 4156 | 0.364 | 0.7889 | No |
| 58 | DCAF13 | DDB1 and CUL4 associated factor 13 [Source:HGNC Symbol;Acc:HGNC:24535] | 4240 | 0.348 | 0.7913 | No |
| 59 | WDR36 | WD repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:30696] | 4486 | 0.310 | 0.7888 | No |
| 60 | NGDN | neuroguidin [Source:HGNC Symbol;Acc:HGNC:20271] | 4796 | 0.265 | 0.7840 | No |
| 61 | RRP1 | ribosomal RNA processing 1 [Source:HGNC Symbol;Acc:HGNC:18785] | 5449 | 0.162 | 0.7686 | No |
| 62 | FAM207A | family with sequence similarity 207 member A [Source:HGNC Symbol;Acc:HGNC:15811] | 5504 | 0.153 | 0.7691 | No |
| 63 | UTP11 | UTP11 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24329] | 5713 | 0.126 | 0.7652 | No |
| 64 | RRP1B | ribosomal RNA processing 1B [Source:HGNC Symbol;Acc:HGNC:23818] | 5816 | 0.112 | 0.7639 | No |
| 65 | NOC2L | NOC2 like nucleolar associated transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:24517] | 27528 | -0.010 | 0.1775 | No |
| 66 | NOP9 | NOP9 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:19826] | 27536 | -0.011 | 0.1775 | No |
| 67 | RRP7BP | ribosomal RNA processing 7 homolog B, pseudogene [Source:HGNC Symbol;Acc:HGNC:30454] | 27739 | -0.038 | 0.1725 | No |
| 68 | UTP14C | UTP14C small subunit processome component [Source:HGNC Symbol;Acc:HGNC:20321] | 28143 | -0.086 | 0.1628 | No |
| 69 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 28224 | -0.098 | 0.1619 | No |
| 70 | UTP14A | UTP14A small subunit processome component [Source:HGNC Symbol;Acc:HGNC:10665] | 28512 | -0.131 | 0.1559 | No |
| 71 | UTP3 | UTP3 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24477] | 30173 | -0.333 | 0.1155 | No |
| 72 | NSA2 | NSA2 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:30728] | 30498 | -0.378 | 0.1118 | No |
| 73 | RPS7 | ribosomal protein S7 [Source:HGNC Symbol;Acc:HGNC:10440] | 31069 | -0.462 | 0.1026 | No |
| 74 | NOB1 | NIN1 (RPN12) binding protein 1 homolog [Source:HGNC Symbol;Acc:HGNC:29540] | 31138 | -0.472 | 0.1070 | No |
| 75 | ZNF622 | zinc finger protein 622 [Source:HGNC Symbol;Acc:HGNC:30958] | 31953 | -0.604 | 0.0931 | No |
| 76 | IMP3 | IMP U3 small nucleolar ribonucleoprotein 3 [Source:HGNC Symbol;Acc:HGNC:14497] | 33328 | -0.931 | 0.0684 | No |
| 77 | FBXW9 | F-box and WD repeat domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28136] | 33384 | -0.945 | 0.0795 | No |
| 78 | PRKDC | protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413] | 35043 | -1.541 | 0.0553 | No |
