Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GOCC_T_CELL_RECEPTOR_COMPLEX |
| Enrichment Score (ES) | 0.73217326 |
| Normalized Enrichment Score (NES) | 1.9000155 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0062181023 |
| FWER p-Value | 0.041 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 522 | 2.042 | 0.3362 | Yes |
| 2 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 933 | 1.494 | 0.5814 | Yes |
| 3 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 1746 | 1.007 | 0.7322 | Yes |
| 4 | ZAP70 | zeta chain of T cell receptor associated protein kinase 70 [Source:HGNC Symbol;Acc:HGNC:12858] | 5420 | 0.167 | 0.6614 | No |
| 5 | CD6 | CD6 molecule [Source:HGNC Symbol;Acc:HGNC:1691] | 6084 | 0.078 | 0.6569 | No |
| 6 | CD247 | CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677] | 8457 | 0.000 | 0.5927 | No |
| 7 | TRAV29DV5 | T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12127] | 8704 | 0.000 | 0.5861 | No |
| 8 | TRAV12-3 | T cell receptor alpha variable 12-3 [Source:HGNC Symbol;Acc:HGNC:12107] | 8995 | 0.000 | 0.5782 | No |
| 9 | TRAV12-2 | T cell receptor alpha variable 12-2 [Source:HGNC Symbol;Acc:HGNC:12106] | 8996 | 0.000 | 0.5782 | No |
| 10 | TRAV12-1 | T cell receptor alpha variable 12-1 [Source:HGNC Symbol;Acc:HGNC:12105] | 8997 | 0.000 | 0.5782 | No |
| 11 | TRAV38-1 | T cell receptor alpha variable 38-1 [Source:HGNC Symbol;Acc:HGNC:12137] | 9073 | 0.000 | 0.5762 | No |
| 12 | TRAV13-2 | T cell receptor alpha variable 13-2 [Source:HGNC Symbol;Acc:HGNC:12109] | 9435 | 0.000 | 0.5664 | No |
| 13 | TRAV13-1 | T cell receptor alpha variable 13-1 [Source:HGNC Symbol;Acc:HGNC:12108] | 9436 | 0.000 | 0.5664 | No |
| 14 | TRAV41 | T cell receptor alpha variable 41 [Source:HGNC Symbol;Acc:HGNC:12142] | 9679 | 0.000 | 0.5599 | No |
| 15 | TRAV40 | T cell receptor alpha variable 40 [Source:HGNC Symbol;Acc:HGNC:12141] | 9680 | 0.000 | 0.5599 | No |
| 16 | TRAV39 | T cell receptor alpha variable 39 [Source:HGNC Symbol;Acc:HGNC:12139] | 9683 | 0.000 | 0.5598 | No |
| 17 | TRAV30 | T cell receptor alpha variable 30 [Source:HGNC Symbol;Acc:HGNC:12129] | 9690 | 0.000 | 0.5597 | No |
| 18 | TRAV35 | T cell receptor alpha variable 35 [Source:HGNC Symbol;Acc:HGNC:12134] | 9693 | 0.000 | 0.5596 | No |
| 19 | TRAV34 | T cell receptor alpha variable 34 [Source:HGNC Symbol;Acc:HGNC:12133] | 9694 | 0.000 | 0.5596 | No |
| 20 | TRAV27 | T cell receptor alpha variable 27 [Source:HGNC Symbol;Acc:HGNC:12125] | 9701 | 0.000 | 0.5595 | No |
| 21 | TRBV25-1 | T cell receptor beta variable 25-1 [Source:HGNC Symbol;Acc:HGNC:12205] | 10345 | 0.000 | 0.5421 | No |
| 22 | TRBV24-1 | T cell receptor beta variable 24-1 [Source:HGNC Symbol;Acc:HGNC:12203] | 10648 | 0.000 | 0.5339 | No |
| 23 | TRBV23-1 | T cell receptor beta variable 23-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12201] | 10918 | 0.000 | 0.5266 | No |
| 24 | TRBV20-1 | T cell receptor beta variable 20-1 [Source:HGNC Symbol;Acc:HGNC:12196] | 11880 | 0.000 | 0.5006 | No |
| 25 | TRAV23DV6 | T cell receptor alpha variable 23/delta variable 6 [Source:HGNC Symbol;Acc:HGNC:12120] | 11929 | 0.000 | 0.4993 | No |
| 26 | TRBJ2-6 | T cell receptor beta joining 2-6 [Source:HGNC Symbol;Acc:HGNC:12174] | 12524 | 0.000 | 0.4833 | No |
| 27 | TRBJ2-5 | T cell receptor beta joining 2-5 [Source:HGNC Symbol;Acc:HGNC:12173] | 12525 | 0.000 | 0.4833 | No |
| 28 | TRBJ2-7 | T cell receptor beta joining 2-7 [Source:HGNC Symbol;Acc:HGNC:12175] | 12527 | 0.000 | 0.4832 | No |
| 29 | TRBJ2-2 | T cell receptor beta joining 2-2 [Source:HGNC Symbol;Acc:HGNC:12169] | 12528 | 0.000 | 0.4832 | No |
| 30 | TRBJ2-1 | T cell receptor beta joining 2-1 [Source:HGNC Symbol;Acc:HGNC:12168] | 12530 | 0.000 | 0.4832 | No |
| 31 | TRBJ2-4 | T cell receptor beta joining 2-4 [Source:HGNC Symbol;Acc:HGNC:12172] | 12531 | 0.000 | 0.4832 | No |
| 32 | TRBJ2-3 | T cell receptor beta joining 2-3 [Source:HGNC Symbol;Acc:HGNC:12171] | 12532 | 0.000 | 0.4832 | No |
| 33 | TRAV1-1 | T cell receptor alpha variable 1-1 [Source:HGNC Symbol;Acc:HGNC:12101] | 13333 | 0.000 | 0.4616 | No |
| 34 | TRAV1-2 | T cell receptor alpha variable 1-2 [Source:HGNC Symbol;Acc:HGNC:12102] | 13334 | 0.000 | 0.4616 | No |
| 35 | TRAV8-4 | T cell receptor alpha variable 8-4 [Source:HGNC Symbol;Acc:HGNC:12149] | 13783 | 0.000 | 0.4494 | No |
| 36 | TRAV8-6 | T cell receptor alpha variable 8-6 [Source:HGNC Symbol;Acc:HGNC:12151] | 13785 | 0.000 | 0.4494 | No |
| 37 | TRAV8-1 | T cell receptor alpha variable 8-1 [Source:HGNC Symbol;Acc:HGNC:12146] | 13788 | 0.000 | 0.4494 | No |
| 38 | TRAV8-2 | T cell receptor alpha variable 8-2 [Source:HGNC Symbol;Acc:HGNC:12147] | 13789 | 0.000 | 0.4494 | No |
| 39 | TRAV8-3 | T cell receptor alpha variable 8-3 [Source:HGNC Symbol;Acc:HGNC:12148] | 13790 | 0.000 | 0.4494 | No |
| 40 | TRAV9-1 | T cell receptor alpha variable 9-1 [Source:HGNC Symbol;Acc:HGNC:12153] | 14178 | 0.000 | 0.4389 | No |
| 41 | TRAV9-2 | T cell receptor alpha variable 9-2 [Source:HGNC Symbol;Acc:HGNC:12154] | 14179 | 0.000 | 0.4389 | No |
| 42 | TRAV26-1 | T cell receptor alpha variable 26-1 [Source:HGNC Symbol;Acc:HGNC:12123] | 15334 | 0.000 | 0.4077 | No |
| 43 | TRAV26-2 | T cell receptor alpha variable 26-2 [Source:HGNC Symbol;Acc:HGNC:12124] | 15335 | 0.000 | 0.4077 | No |
| 44 | TRDD1 | T cell receptor delta diversity 1 [Source:HGNC Symbol;Acc:HGNC:12254] | 15681 | 0.000 | 0.3984 | No |
| 45 | TRDJ1 | T cell receptor delta joining 1 [Source:HGNC Symbol;Acc:HGNC:12257] | 15745 | 0.000 | 0.3966 | No |
| 46 | TRDV2 | T cell receptor delta variable 2 [Source:HGNC Symbol;Acc:HGNC:12263] | 15785 | 0.000 | 0.3956 | No |
| 47 | TRDV3 | T cell receptor delta variable 3 [Source:HGNC Symbol;Acc:HGNC:12264] | 15788 | 0.000 | 0.3955 | No |
| 48 | TRDV1 | T cell receptor delta variable 1 [Source:HGNC Symbol;Acc:HGNC:12262] | 15791 | 0.000 | 0.3955 | No |
| 49 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15869 | 0.000 | 0.3934 | No |
| 50 | TRBV11-1 | T cell receptor beta variable 11-1 [Source:HGNC Symbol;Acc:HGNC:12180] | 16381 | 0.000 | 0.3796 | No |
| 51 | TRBV11-2 | T cell receptor beta variable 11-2 [Source:HGNC Symbol;Acc:HGNC:12181] | 16382 | 0.000 | 0.3796 | No |
| 52 | TRGC2 | T cell receptor gamma constant 2 [Source:HGNC Symbol;Acc:HGNC:12276] | 16398 | 0.000 | 0.3792 | No |
| 53 | TRBV10-1 | T cell receptor beta variable 10-1(gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12177] | 16748 | 0.000 | 0.3697 | No |
| 54 | TRBV10-2 | T cell receptor beta variable 10-2 [Source:HGNC Symbol;Acc:HGNC:12178] | 16749 | 0.000 | 0.3697 | No |
| 55 | TRAV36DV7 | T cell receptor alpha variable 36/delta variable 7 [Source:HGNC Symbol;Acc:HGNC:12135] | 16893 | 0.000 | 0.3659 | No |
| 56 | TRGJ2 | T cell receptor gamma joining 2 [Source:HGNC Symbol;Acc:HGNC:12278] | 17198 | 0.000 | 0.3576 | No |
| 57 | TRGV3 | T cell receptor gamma variable 3 [Source:HGNC Symbol;Acc:HGNC:12288] | 17220 | 0.000 | 0.3571 | No |
| 58 | TRGV4 | T cell receptor gamma variable 4 [Source:HGNC Symbol;Acc:HGNC:12289] | 17221 | 0.000 | 0.3571 | No |
| 59 | TRGV1 | T cell receptor gamma variable 1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12284] | 17222 | 0.000 | 0.3571 | No |
| 60 | TRGV2 | T cell receptor gamma variable 2 [Source:HGNC Symbol;Acc:HGNC:12287] | 17223 | 0.000 | 0.3571 | No |
| 61 | TRGV9 | T cell receptor gamma variable 9 [Source:HGNC Symbol;Acc:HGNC:12295] | 17224 | 0.000 | 0.3571 | No |
| 62 | TRGV8 | T cell receptor gamma variable 8 [Source:HGNC Symbol;Acc:HGNC:12294] | 17227 | 0.000 | 0.3570 | No |
| 63 | TRGV5 | T cell receptor gamma variable 5 [Source:HGNC Symbol;Acc:HGNC:12290] | 17228 | 0.000 | 0.3570 | No |
| 64 | TRBV6-4 | T cell receptor beta variable 6-4 [Source:HGNC Symbol;Acc:HGNC:12229] | 18100 | 0.000 | 0.3335 | No |
| 65 | TRBV6-1 | T cell receptor beta variable 6-1 [Source:HGNC Symbol;Acc:HGNC:12226] | 18101 | 0.000 | 0.3335 | No |
| 66 | TRBV6-7 | T cell receptor beta variable 6-7 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12232] | 18102 | 0.000 | 0.3335 | No |
| 67 | TRBV6-8 | T cell receptor beta variable 6-8 [Source:HGNC Symbol;Acc:HGNC:12233] | 18103 | 0.000 | 0.3335 | No |
| 68 | TRBV6-5 | T cell receptor beta variable 6-5 [Source:HGNC Symbol;Acc:HGNC:12230] | 18105 | 0.000 | 0.3334 | No |
| 69 | TRBV6-6 | T cell receptor beta variable 6-6 [Source:HGNC Symbol;Acc:HGNC:12231] | 18106 | 0.000 | 0.3334 | No |
| 70 | TRBV5-1 | T cell receptor beta variable 5-1 [Source:HGNC Symbol;Acc:HGNC:12218] | 18324 | 0.000 | 0.3276 | No |
| 71 | TRBV5-4 | T cell receptor beta variable 5-4 [Source:HGNC Symbol;Acc:HGNC:12221] | 18325 | 0.000 | 0.3276 | No |
| 72 | TRBV5-5 | T cell receptor beta variable 5-5 [Source:HGNC Symbol;Acc:HGNC:12222] | 18326 | 0.000 | 0.3276 | No |
| 73 | TRBV5-3 | T cell receptor beta variable 5-3 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12220] | 18328 | 0.000 | 0.3275 | No |
| 74 | TRBV5-6 | T cell receptor beta variable 5-6 [Source:HGNC Symbol;Acc:HGNC:12223] | 18329 | 0.000 | 0.3275 | No |
| 75 | TRBV5-7 | T cell receptor beta variable 5-7 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12224] | 18330 | 0.000 | 0.3275 | No |
| 76 | TRBV7-3 | T cell receptor beta variable 7-3 [Source:HGNC Symbol;Acc:HGNC:12237] | 18429 | 0.000 | 0.3249 | No |
| 77 | TRBV7-1 | T cell receptor beta variable 7-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12235] | 18430 | 0.000 | 0.3249 | No |
| 78 | TRBV7-6 | T cell receptor beta variable 7-6 [Source:HGNC Symbol;Acc:HGNC:12240] | 18431 | 0.000 | 0.3249 | No |
| 79 | TRBV7-7 | T cell receptor beta variable 7-7 [Source:HGNC Symbol;Acc:HGNC:12241] | 18432 | 0.000 | 0.3249 | No |
| 80 | TRBV7-4 | T cell receptor beta variable 7-4 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12238] | 18433 | 0.000 | 0.3249 | No |
| 81 | TRBV3-1 | T cell receptor beta variable 3-1 [Source:HGNC Symbol;Acc:HGNC:12212] | 19115 | 0.000 | 0.3065 | No |
| 82 | TRBV4-1 | T cell receptor beta variable 4-1 [Source:HGNC Symbol;Acc:HGNC:12215] | 19356 | 0.000 | 0.3000 | No |
| 83 | TRBV4-2 | T cell receptor beta variable 4-2 [Source:HGNC Symbol;Acc:HGNC:12216] | 19358 | 0.000 | 0.2999 | No |
| 84 | TRAV14DV4 | T cell receptor alpha variable 14/delta variable 4 [Source:HGNC Symbol;Acc:HGNC:12110] | 20209 | 0.000 | 0.2769 | No |
| 85 | TRAC | T cell receptor alpha constant [Source:HGNC Symbol;Acc:HGNC:12029] | 21591 | 0.000 | 0.2396 | No |
| 86 | TRDC | T cell receptor delta constant [Source:HGNC Symbol;Acc:HGNC:12253] | 21625 | 0.000 | 0.2387 | No |
| 87 | TRBV29-1 | T cell receptor beta variable 29-1 [Source:HGNC Symbol;Acc:HGNC:12210] | 22541 | 0.000 | 0.2139 | No |
| 88 | TRBV30 | T cell receptor beta variable 30 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12214] | 22676 | 0.000 | 0.2103 | No |
| 89 | TRBV28 | T cell receptor beta variable 28 [Source:HGNC Symbol;Acc:HGNC:12209] | 22678 | 0.000 | 0.2103 | No |
| 90 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 22682 | 0.000 | 0.2102 | No |
| 91 | TRBV19 | T cell receptor beta variable 19 [Source:HGNC Symbol;Acc:HGNC:12194] | 22688 | 0.000 | 0.2101 | No |
| 92 | CD3G | CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675] | 23004 | 0.000 | 0.2016 | No |
| 93 | CD3E | CD3e molecule [Source:HGNC Symbol;Acc:HGNC:1674] | 23007 | 0.000 | 0.2015 | No |
| 94 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 23008 | 0.000 | 0.2015 | No |
| 95 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 23102 | 0.000 | 0.1990 | No |
| 96 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 23103 | 0.000 | 0.1990 | No |
| 97 | TRAV38-2DV8 | T cell receptor alpha variable 38-2/delta variable 8 [Source:HGNC Symbol;Acc:HGNC:12138] | 23890 | 0.000 | 0.1777 | No |
| 98 | SKAP1 | src kinase associated phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15605] | 24041 | 0.000 | 0.1737 | No |
| 99 | TRGV10 | T cell receptor gamma variable 10 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12285] | 24950 | 0.000 | 0.1491 | No |
| 100 | TRGV11 | T cell receptor gamma variable 11 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12286] | 24952 | 0.000 | 0.1491 | No |
| 101 | TRAV20 | T cell receptor alpha variable 20 [Source:HGNC Symbol;Acc:HGNC:12117] | 25262 | 0.000 | 0.1407 | No |
| 102 | TRAV22 | T cell receptor alpha variable 22 [Source:HGNC Symbol;Acc:HGNC:12119] | 25263 | 0.000 | 0.1407 | No |
| 103 | TRAV21 | T cell receptor alpha variable 21 [Source:HGNC Symbol;Acc:HGNC:12118] | 25264 | 0.000 | 0.1407 | No |
| 104 | TRAV24 | T cell receptor alpha variable 24 [Source:HGNC Symbol;Acc:HGNC:12121] | 25265 | 0.000 | 0.1407 | No |
| 105 | TRAV25 | T cell receptor alpha variable 25 [Source:HGNC Symbol;Acc:HGNC:12122] | 25267 | 0.000 | 0.1407 | No |
| 106 | TRAV17 | T cell receptor alpha variable 17 [Source:HGNC Symbol;Acc:HGNC:12113] | 25272 | 0.000 | 0.1406 | No |
| 107 | TRAV16 | T cell receptor alpha variable 16 [Source:HGNC Symbol;Acc:HGNC:12112] | 25273 | 0.000 | 0.1406 | No |
| 108 | TRAV19 | T cell receptor alpha variable 19 [Source:HGNC Symbol;Acc:HGNC:12115] | 25274 | 0.000 | 0.1406 | No |
| 109 | TRAV18 | T cell receptor alpha variable 18 [Source:HGNC Symbol;Acc:HGNC:12114] | 25275 | 0.000 | 0.1406 | No |
| 110 | TRAV10 | T cell receptor alpha variable 10 [Source:HGNC Symbol;Acc:HGNC:12103] | 25281 | 0.000 | 0.1404 | No |
| 111 | TRBC2 | T cell receptor beta constant 2 [Source:HGNC Symbol;Acc:HGNC:12157] | 26805 | 0.000 | 0.0992 | No |
| 112 | TRBV9 | T cell receptor beta variable 9 [Source:HGNC Symbol;Acc:HGNC:12246] | 27075 | 0.000 | 0.0920 | No |
| 113 | TRBV2 | T cell receptor beta variable 2 [Source:HGNC Symbol;Acc:HGNC:12195] | 27076 | 0.000 | 0.0920 | No |
| 114 | TRAJ3 | T cell receptor alpha joining 3 [Source:HGNC Symbol;Acc:HGNC:12059] | 27182 | 0.000 | 0.0891 | No |
| 115 | TRAV2 | T cell receptor alpha variable 2 [Source:HGNC Symbol;Acc:HGNC:12116] | 27457 | 0.000 | 0.0817 | No |
| 116 | TRAV7 | T cell receptor alpha variable 7 [Source:HGNC Symbol;Acc:HGNC:12145] | 27458 | 0.000 | 0.0817 | No |
| 117 | TRAV4 | T cell receptor alpha variable 4 [Source:HGNC Symbol;Acc:HGNC:12140] | 27461 | 0.000 | 0.0817 | No |
| 118 | TRAV3 | T cell receptor alpha variable 3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12128] | 27464 | 0.000 | 0.0816 | No |
| 119 | TRAV6 | T cell receptor alpha variable 6 [Source:HGNC Symbol;Acc:HGNC:12144] | 27465 | 0.000 | 0.0816 | No |
| 120 | TRAV5 | T cell receptor alpha variable 5 [Source:HGNC Symbol;Acc:HGNC:12143] | 27467 | 0.000 | 0.0816 | No |
| 121 | TRAT1 | T cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30698] | 27474 | 0.000 | 0.0814 | No |
| 122 | CEACAM1 | CEA cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:1814] | 29390 | -0.237 | 0.0702 | No |
| 123 | STOML2 | stomatin like 2 [Source:HGNC Symbol;Acc:HGNC:14559] | 30264 | -0.346 | 0.1059 | No |
| 124 | PTPN6 | protein tyrosine phosphatase non-receptor type 6 [Source:HGNC Symbol;Acc:HGNC:9658] | 31042 | -0.459 | 0.1636 | No |
