Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HP_EMBRYONAL_NEOPLASM |
| Enrichment Score (ES) | -0.8007014 |
| Normalized Enrichment Score (NES) | -1.6246467 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05483667 |
| FWER p-Value | 0.415 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CDC73 | cell division cycle 73 [Source:HGNC Symbol;Acc:HGNC:16783] | 2014 | 0.894 | -0.0381 | No |
| 2 | DHX37 | DEAH-box helicase 37 [Source:HGNC Symbol;Acc:HGNC:17210] | 2284 | 0.791 | -0.0310 | No |
| 3 | TTC37 | tetratricopeptide repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:23639] | 3317 | 0.520 | -0.0494 | No |
| 4 | KCNQ1OT1 | KCNQ1 opposite strand/antisense transcript 1 [Source:HGNC Symbol;Acc:HGNC:6295] | 3672 | 0.448 | -0.0509 | No |
| 5 | NR5A1 | nuclear receptor subfamily 5 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7983] | 5043 | 0.224 | -0.0838 | No |
| 6 | APC2 | APC regulator of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:24036] | 7034 | 0.000 | -0.1375 | No |
| 7 | DMRT3 | doublesex and mab-3 related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:13909] | 9897 | 0.000 | -0.2148 | No |
| 8 | KCNQ1 | potassium voltage-gated channel subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:6294] | 10162 | 0.000 | -0.2219 | No |
| 9 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 10174 | 0.000 | -0.2222 | No |
| 10 | RTL1 | retrotransposon Gag like 1 [Source:HGNC Symbol;Acc:HGNC:14665] | 10761 | 0.000 | -0.2381 | No |
| 11 | SRY | sex determining region Y [Source:HGNC Symbol;Acc:HGNC:11311] | 12646 | 0.000 | -0.2889 | No |
| 12 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12703 | 0.000 | -0.2905 | No |
| 13 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12851 | 0.000 | -0.2944 | No |
| 14 | BMPER | BMP binding endothelial regulator [Source:HGNC Symbol;Acc:HGNC:24154] | 13012 | 0.000 | -0.2987 | No |
| 15 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13736 | 0.000 | -0.3183 | No |
| 16 | WT1 | WT1 transcription factor [Source:HGNC Symbol;Acc:HGNC:12796] | 13781 | 0.000 | -0.3195 | No |
| 17 | SETBP1 | SET binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15573] | 14117 | 0.000 | -0.3285 | No |
| 18 | DZIP1L | DAZ interacting zinc finger protein 1 like [Source:HGNC Symbol;Acc:HGNC:26551] | 14339 | 0.000 | -0.3345 | No |
| 19 | MEG3 | maternally expressed 3 [Source:HGNC Symbol;Acc:HGNC:14575] | 16458 | 0.000 | -0.3917 | No |
| 20 | DLK1 | delta like non-canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:2907] | 16777 | 0.000 | -0.4003 | No |
| 21 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17182 | 0.000 | -0.4112 | No |
| 22 | NR0B1 | nuclear receptor subfamily 0 group B member 1 [Source:HGNC Symbol;Acc:HGNC:7960] | 18836 | 0.000 | -0.4558 | No |
| 23 | MNX1 | motor neuron and pancreas homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4979] | 19499 | 0.000 | -0.4737 | No |
| 24 | GPC3 | glypican 3 [Source:HGNC Symbol;Acc:HGNC:4451] | 23062 | 0.000 | -0.5699 | No |
| 25 | GPC4 | glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452] | 23068 | 0.000 | -0.5700 | No |
| 26 | ALX4 | ALX homeobox 4 [Source:HGNC Symbol;Acc:HGNC:450] | 24472 | 0.000 | -0.6079 | No |
| 27 | POU6F2 | POU class 6 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:21694] | 25391 | 0.000 | -0.6327 | No |
| 28 | SOX9 | SRY-box transcription factor 9 [Source:HGNC Symbol;Acc:HGNC:11204] | 26145 | 0.000 | -0.6530 | No |
| 29 | DICER1 | dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] | 27603 | -0.021 | -0.6920 | No |
| 30 | SLC22A18 | solute carrier family 22 member 18 [Source:HGNC Symbol;Acc:HGNC:10964] | 28049 | -0.073 | -0.7027 | No |
| 31 | BUB3 | BUB3 mitotic checkpoint protein [Source:HGNC Symbol;Acc:HGNC:1151] | 28342 | -0.112 | -0.7086 | No |
| 32 | SKIV2L | Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:10898] | 28527 | -0.132 | -0.7111 | No |
| 33 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 29665 | -0.274 | -0.7369 | No |
| 34 | VAMP7 | vesicle associated membrane protein 7 [Source:HGNC Symbol;Acc:HGNC:11486] | 30504 | -0.379 | -0.7526 | No |
| 35 | ZFPM2 | zinc finger protein, FOG family member 2 [Source:HGNC Symbol;Acc:HGNC:16700] | 30737 | -0.412 | -0.7514 | No |
| 36 | APC | APC regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:583] | 31295 | -0.499 | -0.7574 | No |
| 37 | DIS3L2 | DIS3 like 3'-5' exoribonuclease 2 [Source:HGNC Symbol;Acc:HGNC:28648] | 31542 | -0.538 | -0.7542 | No |
| 38 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 33264 | -0.912 | -0.7841 | Yes |
| 39 | TRIM28 | tripartite motif containing 28 [Source:HGNC Symbol;Acc:HGNC:16384] | 33276 | -0.916 | -0.7678 | Yes |
| 40 | NSD1 | nuclear receptor binding SET domain protein 1 [Source:HGNC Symbol;Acc:HGNC:14234] | 33325 | -0.930 | -0.7522 | Yes |
| 41 | SETD2 | SET domain containing 2, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:18420] | 33459 | -0.962 | -0.7383 | Yes |
| 42 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975] | 33799 | -1.053 | -0.7283 | Yes |
| 43 | REST | RE1 silencing transcription factor [Source:HGNC Symbol;Acc:HGNC:9966] | 33974 | -1.106 | -0.7129 | Yes |
| 44 | HDAC4 | histone deacetylase 4 [Source:HGNC Symbol;Acc:HGNC:14063] | 34201 | -1.179 | -0.6975 | Yes |
| 45 | FIBP | FGF1 intracellular binding protein [Source:HGNC Symbol;Acc:HGNC:3705] | 34217 | -1.187 | -0.6764 | Yes |
| 46 | EXT2 | exostosin glycosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:3513] | 34386 | -1.248 | -0.6582 | Yes |
| 47 | MSH3 | mutS homolog 3 [Source:HGNC Symbol;Acc:HGNC:7326] | 35134 | -1.586 | -0.6496 | Yes |
| 48 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 35234 | -1.641 | -0.6224 | Yes |
| 49 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35320 | -1.686 | -0.5940 | Yes |
| 50 | CEP57 | centrosomal protein 57 [Source:HGNC Symbol;Acc:HGNC:30794] | 35418 | -1.743 | -0.5650 | Yes |
| 51 | BLM | BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:1058] | 35779 | -1.982 | -0.5387 | Yes |
| 52 | PHF21A | PHD finger protein 21A [Source:HGNC Symbol;Acc:HGNC:24156] | 35848 | -2.042 | -0.5034 | Yes |
| 53 | PTCH1 | patched 1 [Source:HGNC Symbol;Acc:HGNC:9585] | 36066 | -2.205 | -0.4692 | Yes |
| 54 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.4293 | Yes |
| 55 | WWOX | WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799] | 36355 | -2.490 | -0.3909 | Yes |
| 56 | PALB2 | partner and localizer of BRCA2 [Source:HGNC Symbol;Acc:HGNC:26144] | 36542 | -2.740 | -0.3461 | Yes |
| 57 | TRIM37 | tripartite motif containing 37 [Source:HGNC Symbol;Acc:HGNC:7523] | 36557 | -2.769 | -0.2962 | Yes |
| 58 | CHEK2 | checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627] | 36675 | -2.952 | -0.2457 | Yes |
| 59 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6848] | 36852 | -3.305 | -0.1903 | Yes |
| 60 | SLC37A4 | solute carrier family 37 member 4 [Source:HGNC Symbol;Acc:HGNC:4061] | 36894 | -3.464 | -0.1285 | Yes |
| 61 | PAX6 | paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620] | 36903 | -3.507 | -0.0649 | Yes |
| 62 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36995 | -3.849 | 0.0026 | Yes |
