Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CAHOY_OLIGODENDROCUTIC |
| Enrichment Score (ES) | -0.6738112 |
| Normalized Enrichment Score (NES) | -1.4358613 |
| Nominal p-value | 0.009302326 |
| FDR q-value | 0.05773474 |
| FWER p-Value | 0.353 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 485 | 2.127 | 0.0120 | No |
| 2 | DOCK10 | dedicator of cytokinesis 10 [Source:HGNC Symbol;Acc:HGNC:23479] | 629 | 1.873 | 0.0303 | No |
| 3 | EFHD2 | EF-hand domain family member D2 [Source:HGNC Symbol;Acc:HGNC:28670] | 878 | 1.543 | 0.0419 | No |
| 4 | USP16 | ubiquitin specific peptidase 16 [Source:HGNC Symbol;Acc:HGNC:12614] | 1387 | 1.159 | 0.0418 | No |
| 5 | ADGRL2 | adhesion G protein-coupled receptor L2 [Source:HGNC Symbol;Acc:HGNC:18582] | 1837 | 0.969 | 0.0412 | No |
| 6 | BCAS1 | brain enriched myelin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:974] | 2087 | 0.862 | 0.0446 | No |
| 7 | ZNF276 | zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330] | 2295 | 0.788 | 0.0483 | No |
| 8 | PUS7 | pseudouridine synthase 7 [Source:HGNC Symbol;Acc:HGNC:26033] | 3006 | 0.589 | 0.0361 | No |
| 9 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 3688 | 0.444 | 0.0230 | No |
| 10 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 4064 | 0.379 | 0.0173 | No |
| 11 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 4098 | 0.375 | 0.0208 | No |
| 12 | HIP1R | huntingtin interacting protein 1 related [Source:HGNC Symbol;Acc:HGNC:18415] | 4567 | 0.298 | 0.0117 | No |
| 13 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 4780 | 0.266 | 0.0091 | No |
| 14 | TLCD3A | TLC domain containing 3A [Source:HGNC Symbol;Acc:HGNC:29646] | 5114 | 0.214 | 0.0027 | No |
| 15 | BCR | BCR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:1014] | 6342 | 0.047 | -0.0299 | No |
| 16 | POP4 | POP4 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30081] | 6445 | 0.034 | -0.0323 | No |
| 17 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 6478 | 0.032 | -0.0328 | No |
| 18 | NCMAP | non-compact myelin associated protein [Source:HGNC Symbol;Acc:HGNC:29332] | 7254 | 0.000 | -0.0537 | No |
| 19 | CNTNAP2 | contactin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:13830] | 7736 | 0.000 | -0.0667 | No |
| 20 | FA2H | fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197] | 7984 | 0.000 | -0.0734 | No |
| 21 | MAP6D1 | MAP6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25753] | 8763 | 0.000 | -0.0945 | No |
| 22 | SOX10 | SRY-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11190] | 9131 | 0.000 | -0.1044 | No |
| 23 | NINJ2 | ninjurin 2 [Source:HGNC Symbol;Acc:HGNC:7825] | 10163 | 0.000 | -0.1323 | No |
| 24 | PLLP | plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553] | 10359 | 0.000 | -0.1375 | No |
| 25 | TSPAN2 | tetraspanin 2 [Source:HGNC Symbol;Acc:HGNC:20659] | 11774 | 0.000 | -0.1757 | No |
| 26 | ATP10B | ATPase phospholipid transporting 10B (putative) [Source:HGNC Symbol;Acc:HGNC:13543] | 12406 | 0.000 | -0.1928 | No |
| 27 | TENM1 | teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117] | 12979 | 0.000 | -0.2083 | No |
| 28 | CDR2L | cerebellar degeneration related protein 2 like [Source:HGNC Symbol;Acc:HGNC:29999] | 13294 | 0.000 | -0.2168 | No |
| 29 | DMRTA1 | DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826] | 15101 | 0.000 | -0.2656 | No |
| 30 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16132 | 0.000 | -0.2934 | No |
| 31 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16450 | 0.000 | -0.3020 | No |
| 32 | GPR17 | G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471] | 17510 | 0.000 | -0.3306 | No |
| 33 | SEMA3D | semaphorin 3D [Source:HGNC Symbol;Acc:HGNC:10726] | 17881 | 0.000 | -0.3406 | No |
| 34 | BFSP2 | beaded filament structural protein 2 [Source:HGNC Symbol;Acc:HGNC:1041] | 18216 | 0.000 | -0.3497 | No |
| 35 | FEZF2 | FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506] | 18643 | 0.000 | -0.3612 | No |
| 36 | AGAP11 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 [Source:HGNC Symbol;Acc:HGNC:29421] | 19636 | 0.000 | -0.3880 | No |
| 37 | DUSP15 | dual specificity phosphatase 15 [Source:HGNC Symbol;Acc:HGNC:16236] | 20570 | 0.000 | -0.4132 | No |
| 38 | GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488] | 20675 | 0.000 | -0.4160 | No |
| 39 | GJE1 | gap junction protein epsilon 1 [Source:HGNC Symbol;Acc:HGNC:33251] | 20937 | 0.000 | -0.4231 | No |
| 40 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21359 | 0.000 | -0.4345 | No |
| 41 | ZNF536 | zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] | 21838 | 0.000 | -0.4474 | No |
| 42 | FAM89A | family with sequence similarity 89 member A [Source:HGNC Symbol;Acc:HGNC:25057] | 22628 | 0.000 | -0.4687 | No |
| 43 | LHFPL6 | LHFPL tetraspan subfamily member 6 [Source:HGNC Symbol;Acc:HGNC:6586] | 22687 | 0.000 | -0.4703 | No |
| 44 | CCN2 | cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500] | 22954 | 0.000 | -0.4775 | No |
| 45 | RBM11 | RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897] | 23649 | 0.000 | -0.4962 | No |
| 46 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 24435 | 0.000 | -0.5175 | No |
| 47 | UGT8 | UDP glycosyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:12555] | 24887 | 0.000 | -0.5296 | No |
| 48 | FIGN | fidgetin, microtubule severing factor [Source:HGNC Symbol;Acc:HGNC:13285] | 26075 | 0.000 | -0.5617 | No |
| 49 | SOX8 | SRY-box transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:11203] | 26144 | 0.000 | -0.5636 | No |
| 50 | SPEG | striated muscle enriched protein kinase [Source:HGNC Symbol;Acc:HGNC:16901] | 27711 | -0.036 | -0.6055 | No |
| 51 | PRKCQ | protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410] | 27925 | -0.063 | -0.6105 | No |
| 52 | PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9581] | 28377 | -0.116 | -0.6213 | No |
| 53 | GNG8 | G protein subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:19664] | 28421 | -0.121 | -0.6210 | No |
| 54 | GAL3ST1 | galactose-3-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24240] | 28572 | -0.137 | -0.6235 | No |
| 55 | SRPK3 | SRSF protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:11402] | 28997 | -0.189 | -0.6327 | No |
| 56 | NGRN | neugrin, neurite outgrowth associated [Source:HGNC Symbol;Acc:HGNC:18077] | 29029 | -0.193 | -0.6313 | No |
| 57 | BACE1 | beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933] | 29192 | -0.212 | -0.6331 | No |
| 58 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 29486 | -0.249 | -0.6381 | No |
| 59 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 30152 | -0.331 | -0.6522 | No |
| 60 | CSDC2 | cold shock domain containing C2 [Source:HGNC Symbol;Acc:HGNC:30359] | 30163 | -0.332 | -0.6485 | No |
| 61 | NR2C1 | nuclear receptor subfamily 2 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7971] | 31063 | -0.462 | -0.6674 | No |
| 62 | WIPF1 | WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736] | 31302 | -0.500 | -0.6679 | Yes |
| 63 | CPOX | coproporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:2321] | 31401 | -0.513 | -0.6645 | Yes |
| 64 | ERBB3 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 31678 | -0.560 | -0.6653 | Yes |
| 65 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 31843 | -0.583 | -0.6629 | Yes |
| 66 | KCTD1 | potassium channel tetramerization domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18249] | 31967 | -0.609 | -0.6590 | Yes |
| 67 | COL20A1 | collagen type XX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:14670] | 31978 | -0.610 | -0.6521 | Yes |
| 68 | DOCK7 | dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:HGNC:19190] | 32055 | -0.626 | -0.6467 | Yes |
| 69 | DUSP19 | dual specificity phosphatase 19 [Source:HGNC Symbol;Acc:HGNC:18894] | 32357 | -0.690 | -0.6467 | Yes |
| 70 | EPN2 | epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639] | 32603 | -0.747 | -0.6445 | Yes |
| 71 | FBXO7 | F-box protein 7 [Source:HGNC Symbol;Acc:HGNC:13586] | 32759 | -0.782 | -0.6394 | Yes |
| 72 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 32916 | -0.821 | -0.6339 | Yes |
| 73 | RNASEH2B | ribonuclease H2 subunit B [Source:HGNC Symbol;Acc:HGNC:25671] | 33035 | -0.851 | -0.6271 | Yes |
| 74 | SIRT2 | sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886] | 33140 | -0.876 | -0.6195 | Yes |
| 75 | DCPS | decapping enzyme, scavenger [Source:HGNC Symbol;Acc:HGNC:29812] | 33353 | -0.936 | -0.6142 | Yes |
| 76 | RNF122 | ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147] | 33583 | -0.996 | -0.6086 | Yes |
| 77 | PPP1R21 | protein phosphatase 1 regulatory subunit 21 [Source:HGNC Symbol;Acc:HGNC:30595] | 34025 | -1.122 | -0.6072 | Yes |
| 78 | SERINC5 | serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825] | 34071 | -1.136 | -0.5950 | Yes |
| 79 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 34344 | -1.232 | -0.5878 | Yes |
| 80 | RTKN | rhotekin [Source:HGNC Symbol;Acc:HGNC:10466] | 34438 | -1.265 | -0.5754 | Yes |
| 81 | RCBTB1 | RCC1 and BTB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:18243] | 34744 | -1.396 | -0.5671 | Yes |
| 82 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 35097 | -1.567 | -0.5581 | Yes |
| 83 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 35200 | -1.625 | -0.5416 | Yes |
| 84 | AP5Z1 | adaptor related protein complex 5 subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:22197] | 35337 | -1.693 | -0.5253 | Yes |
| 85 | KIAA1958 | KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427] | 35936 | -2.113 | -0.5165 | Yes |
| 86 | PKIG | cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019] | 36139 | -2.271 | -0.4951 | Yes |
| 87 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36247 | -2.372 | -0.4699 | Yes |
| 88 | ABHD8 | abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759] | 36336 | -2.464 | -0.4432 | Yes |
| 89 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36356 | -2.490 | -0.4142 | Yes |
| 90 | CLYBL | citramalyl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:18355] | 36459 | -2.635 | -0.3858 | Yes |
| 91 | IFFO1 | intermediate filament family orphan 1 [Source:HGNC Symbol;Acc:HGNC:24970] | 36586 | -2.811 | -0.3560 | Yes |
| 92 | ELOVL6 | ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] | 36609 | -2.844 | -0.3230 | Yes |
| 93 | MAP3K15 | mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689] | 36641 | -2.889 | -0.2896 | Yes |
| 94 | CILK1 | ciliogenesis associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:21219] | 36787 | -3.160 | -0.2562 | Yes |
| 95 | PLXNB3 | plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105] | 36846 | -3.286 | -0.2189 | Yes |
| 96 | LCORL | ligand dependent nuclear receptor corepressor like [Source:HGNC Symbol;Acc:HGNC:30776] | 36854 | -3.309 | -0.1800 | Yes |
| 97 | PRKAG2 | protein kinase AMP-activated non-catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:9386] | 36918 | -3.549 | -0.1397 | Yes |
| 98 | LRRC75A | leucine rich repeat containing 75A [Source:HGNC Symbol;Acc:HGNC:32403] | 37012 | -3.942 | -0.0956 | Yes |
| 99 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 37014 | -3.953 | -0.0489 | Yes |
| 100 | P4HA2 | prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547] | 37063 | -4.308 | 0.0007 | Yes |
