Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.6655278 |
| Normalized Enrichment Score (NES) | -1.4430895 |
| Nominal p-value | 0.0022883294 |
| FDR q-value | 0.058333497 |
| FWER p-Value | 0.301 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 358 | 2.459 | 0.0121 | No |
| 2 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 397 | 2.367 | 0.0320 | No |
| 3 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 527 | 2.036 | 0.0466 | No |
| 4 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 1048 | 1.396 | 0.0448 | No |
| 5 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 1532 | 1.093 | 0.0415 | No |
| 6 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 2376 | 0.762 | 0.0254 | No |
| 7 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 2584 | 0.699 | 0.0260 | No |
| 8 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 2658 | 0.677 | 0.0300 | No |
| 9 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 3147 | 0.558 | 0.0217 | No |
| 10 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 3238 | 0.536 | 0.0241 | No |
| 11 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 3728 | 0.435 | 0.0147 | No |
| 12 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 3802 | 0.424 | 0.0165 | No |
| 13 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 3854 | 0.415 | 0.0188 | No |
| 14 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 4057 | 0.380 | 0.0167 | No |
| 15 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 4191 | 0.357 | 0.0162 | No |
| 16 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 4406 | 0.322 | 0.0133 | No |
| 17 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 4588 | 0.296 | 0.0110 | No |
| 18 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 4669 | 0.285 | 0.0114 | No |
| 19 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 5113 | 0.214 | 0.0013 | No |
| 20 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 5568 | 0.144 | -0.0097 | No |
| 21 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 5614 | 0.139 | -0.0097 | No |
| 22 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 5898 | 0.100 | -0.0165 | No |
| 23 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 6066 | 0.081 | -0.0203 | No |
| 24 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 6155 | 0.071 | -0.0221 | No |
| 25 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 6475 | 0.032 | -0.0304 | No |
| 26 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 6635 | 0.010 | -0.0346 | No |
| 27 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 7039 | 0.000 | -0.0455 | No |
| 28 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 7303 | 0.000 | -0.0526 | No |
| 29 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 8135 | 0.000 | -0.0751 | No |
| 30 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 8268 | 0.000 | -0.0787 | No |
| 31 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 9422 | 0.000 | -0.1099 | No |
| 32 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 9811 | 0.000 | -0.1204 | No |
| 33 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11498 | 0.000 | -0.1660 | No |
| 34 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 13113 | 0.000 | -0.2096 | No |
| 35 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13408 | 0.000 | -0.2176 | No |
| 36 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13572 | 0.000 | -0.2220 | No |
| 37 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 14146 | 0.000 | -0.2375 | No |
| 38 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14481 | 0.000 | -0.2465 | No |
| 39 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15989 | 0.000 | -0.2873 | No |
| 40 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16359 | 0.000 | -0.2973 | No |
| 41 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 17587 | 0.000 | -0.3305 | No |
| 42 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17918 | 0.000 | -0.3394 | No |
| 43 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17937 | 0.000 | -0.3399 | No |
| 44 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18447 | 0.000 | -0.3537 | No |
| 45 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 21794 | 0.000 | -0.4442 | No |
| 46 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 22481 | 0.000 | -0.4628 | No |
| 47 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 22487 | 0.000 | -0.4629 | No |
| 48 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 22531 | 0.000 | -0.4641 | No |
| 49 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 22728 | 0.000 | -0.4694 | No |
| 50 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 23687 | 0.000 | -0.4953 | No |
| 51 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 25847 | 0.000 | -0.5537 | No |
| 52 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 26039 | 0.000 | -0.5588 | No |
| 53 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27252 | 0.000 | -0.5916 | No |
| 54 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 27982 | -0.066 | -0.6108 | No |
| 55 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 28198 | -0.093 | -0.6158 | No |
| 56 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 28211 | -0.096 | -0.6152 | No |
| 57 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 28219 | -0.098 | -0.6146 | No |
| 58 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 28296 | -0.107 | -0.6157 | No |
| 59 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 28419 | -0.121 | -0.6179 | No |
| 60 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 28799 | -0.163 | -0.6267 | No |
| 61 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 28905 | -0.178 | -0.6280 | No |
| 62 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 29077 | -0.198 | -0.6308 | No |
| 63 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 29299 | -0.225 | -0.6348 | No |
| 64 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 29562 | -0.261 | -0.6396 | No |
| 65 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 29813 | -0.290 | -0.6438 | No |
| 66 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 29956 | -0.307 | -0.6449 | No |
| 67 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 30614 | -0.394 | -0.6592 | No |
| 68 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 30816 | -0.425 | -0.6609 | No |
| 69 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 30988 | -0.451 | -0.6615 | Yes |
| 70 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 31052 | -0.461 | -0.6592 | Yes |
| 71 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 31133 | -0.471 | -0.6571 | Yes |
| 72 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 31253 | -0.492 | -0.6560 | Yes |
| 73 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 31563 | -0.543 | -0.6596 | Yes |
| 74 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 31659 | -0.558 | -0.6572 | Yes |
| 75 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 31677 | -0.560 | -0.6527 | Yes |
| 76 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 31935 | -0.599 | -0.6543 | Yes |
| 77 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 32328 | -0.684 | -0.6589 | Yes |
| 78 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 32446 | -0.710 | -0.6558 | Yes |
| 79 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 32699 | -0.768 | -0.6558 | Yes |
| 80 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 32704 | -0.770 | -0.6491 | Yes |
| 81 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 33224 | -0.900 | -0.6551 | Yes |
| 82 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 33243 | -0.905 | -0.6476 | Yes |
| 83 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 33440 | -0.958 | -0.6444 | Yes |
| 84 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 33584 | -0.997 | -0.6395 | Yes |
| 85 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 33585 | -0.997 | -0.6307 | Yes |
| 86 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 33682 | -1.028 | -0.6241 | Yes |
| 87 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 33915 | -1.085 | -0.6208 | Yes |
| 88 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 34605 | -1.333 | -0.6276 | Yes |
| 89 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 34738 | -1.394 | -0.6189 | Yes |
| 90 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 34741 | -1.395 | -0.6066 | Yes |
| 91 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 34839 | -1.440 | -0.5964 | Yes |
| 92 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 34876 | -1.456 | -0.5845 | Yes |
| 93 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 34923 | -1.482 | -0.5726 | Yes |
| 94 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 34925 | -1.483 | -0.5595 | Yes |
| 95 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 34946 | -1.490 | -0.5469 | Yes |
| 96 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 34983 | -1.505 | -0.5345 | Yes |
| 97 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 35024 | -1.529 | -0.5221 | Yes |
| 98 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 35114 | -1.578 | -0.5105 | Yes |
| 99 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 35141 | -1.590 | -0.4971 | Yes |
| 100 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 35201 | -1.625 | -0.4844 | Yes |
| 101 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 35300 | -1.675 | -0.4722 | Yes |
| 102 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 35366 | -1.714 | -0.4587 | Yes |
| 103 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 35392 | -1.726 | -0.4441 | Yes |
| 104 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 35462 | -1.766 | -0.4304 | Yes |
| 105 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 35568 | -1.827 | -0.4170 | Yes |
| 106 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 35585 | -1.837 | -0.4012 | Yes |
| 107 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 35771 | -1.978 | -0.3887 | Yes |
| 108 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 35850 | -2.043 | -0.3727 | Yes |
| 109 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 36029 | -2.175 | -0.3583 | Yes |
| 110 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 36089 | -2.231 | -0.3401 | Yes |
| 111 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 36130 | -2.263 | -0.3211 | Yes |
| 112 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 36137 | -2.270 | -0.3012 | Yes |
| 113 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 36172 | -2.307 | -0.2817 | Yes |
| 114 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36209 | -2.333 | -0.2620 | Yes |
| 115 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 36244 | -2.370 | -0.2419 | Yes |
| 116 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 36302 | -2.429 | -0.2220 | Yes |
| 117 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 36319 | -2.444 | -0.2008 | Yes |
| 118 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 36384 | -2.525 | -0.1801 | Yes |
| 119 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 36385 | -2.525 | -0.1578 | Yes |
| 120 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 36409 | -2.559 | -0.1357 | Yes |
| 121 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 36451 | -2.619 | -0.1136 | Yes |
| 122 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 36500 | -2.681 | -0.0912 | Yes |
| 123 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 36568 | -2.782 | -0.0684 | Yes |
| 124 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 36701 | -2.998 | -0.0454 | Yes |
| 125 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36706 | -3.003 | -0.0189 | Yes |
| 126 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36855 | -3.309 | 0.0064 | Yes |
