Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | KRAS.KIDNEY_UP.V1_DN |
| Enrichment Score (ES) | 0.48891357 |
| Normalized Enrichment Score (NES) | 1.2912378 |
| Nominal p-value | 0.016393442 |
| FDR q-value | 0.12114537 |
| FWER p-Value | 0.469 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PTGER2 | prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594] | 18 | 4.699 | 0.0656 | Yes |
| 2 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 105 | 3.585 | 0.1137 | Yes |
| 3 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 133 | 3.364 | 0.1603 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 143 | 3.299 | 0.2065 | Yes |
| 5 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 220 | 2.934 | 0.2457 | Yes |
| 6 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 240 | 2.829 | 0.2849 | Yes |
| 7 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 288 | 2.633 | 0.3207 | Yes |
| 8 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 296 | 2.608 | 0.3572 | Yes |
| 9 | ACTC1 | actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143] | 320 | 2.541 | 0.3923 | Yes |
| 10 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 356 | 2.464 | 0.4260 | Yes |
| 11 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 770 | 1.658 | 0.4381 | Yes |
| 12 | EFHD1 | EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] | 879 | 1.543 | 0.4569 | Yes |
| 13 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 1230 | 1.265 | 0.4652 | Yes |
| 14 | KCND1 | potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237] | 1246 | 1.256 | 0.4825 | Yes |
| 15 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 1571 | 1.078 | 0.4889 | Yes |
| 16 | HINFP | histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850] | 2613 | 0.692 | 0.4705 | No |
| 17 | DDX51 | DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082] | 2845 | 0.625 | 0.4730 | No |
| 18 | CARD9 | caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391] | 3169 | 0.552 | 0.4720 | No |
| 19 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 3194 | 0.547 | 0.4791 | No |
| 20 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 3213 | 0.541 | 0.4862 | No |
| 21 | KCNN1 | potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290] | 3662 | 0.449 | 0.4804 | No |
| 22 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 4191 | 0.357 | 0.4711 | No |
| 23 | IL23A | interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488] | 4868 | 0.252 | 0.4564 | No |
| 24 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4960 | 0.237 | 0.4573 | No |
| 25 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 5550 | 0.147 | 0.4434 | No |
| 26 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 5684 | 0.130 | 0.4416 | No |
| 27 | RBIS | ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235] | 5766 | 0.120 | 0.4411 | No |
| 28 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 6378 | 0.042 | 0.4252 | No |
| 29 | CBARP | CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617] | 6638 | 0.009 | 0.4183 | No |
| 30 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6780 | 0.000 | 0.4145 | No |
| 31 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6797 | 0.000 | 0.4140 | No |
| 32 | IL1RL2 | interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999] | 7284 | 0.000 | 0.4009 | No |
| 33 | EPHA5 | EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389] | 7794 | 0.000 | 0.3871 | No |
| 34 | ASPN | asporin [Source:HGNC Symbol;Acc:HGNC:14872] | 8123 | 0.000 | 0.3782 | No |
| 35 | SGK2 | serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900] | 8220 | 0.000 | 0.3756 | No |
| 36 | OR7A10 | olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356] | 8432 | 0.000 | 0.3699 | No |
| 37 | PROP1 | PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455] | 8666 | 0.000 | 0.3636 | No |
| 38 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8714 | 0.000 | 0.3623 | No |
| 39 | FOLR2 | folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793] | 9821 | 0.000 | 0.3324 | No |
| 40 | SERHL2 | serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446] | 9902 | 0.000 | 0.3303 | No |
| 41 | KCNF1 | potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246] | 10103 | 0.000 | 0.3248 | No |
| 42 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 10171 | 0.000 | 0.3230 | No |
| 43 | GRM4 | glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596] | 10269 | 0.000 | 0.3204 | No |
| 44 | AADAC | arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] | 10663 | 0.000 | 0.3098 | No |
| 45 | LRRC31 | leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] | 11655 | 0.000 | 0.2830 | No |
| 46 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11754 | 0.000 | 0.2803 | No |
| 47 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11761 | 0.000 | 0.2801 | No |
| 48 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11779 | 0.000 | 0.2797 | No |
| 49 | LMAN1L | lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632] | 12085 | 0.000 | 0.2714 | No |
| 50 | SLC6A20 | solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927] | 12108 | 0.000 | 0.2708 | No |
| 51 | RYR2 | ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484] | 12132 | 0.000 | 0.2702 | No |
| 52 | CNN1 | calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155] | 12514 | 0.000 | 0.2599 | No |
| 53 | ADAMTSL2 | ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631] | 12862 | 0.000 | 0.2505 | No |
| 54 | TENM2 | teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] | 12981 | 0.000 | 0.2473 | No |
| 55 | THRB | thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799] | 13036 | 0.000 | 0.2459 | No |
| 56 | TACR2 | tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527] | 13420 | 0.000 | 0.2355 | No |
| 57 | LILRA4 | leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503] | 13643 | 0.000 | 0.2295 | No |
| 58 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13650 | 0.000 | 0.2293 | No |
| 59 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13736 | 0.000 | 0.2270 | No |
| 60 | IL26 | interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119] | 13970 | 0.000 | 0.2207 | No |
| 61 | TMEM262 | transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389] | 14050 | 0.000 | 0.2186 | No |
| 62 | KRT2 | keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439] | 14354 | 0.000 | 0.2104 | No |
| 63 | B3GALT5 | beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920] | 14667 | 0.000 | 0.2019 | No |
| 64 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898] | 16100 | 0.000 | 0.1632 | No |
| 65 | C3orf36 | chromosome 3 putative open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:26170] | 16127 | 0.000 | 0.1625 | No |
| 66 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16284 | 0.000 | 0.1583 | No |
| 67 | HYAL4 | hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323] | 16365 | 0.000 | 0.1561 | No |
| 68 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17516 | 0.000 | 0.1250 | No |
| 69 | SLC9A3 | solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] | 17586 | 0.000 | 0.1231 | No |
| 70 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17838 | 0.000 | 0.1163 | No |
| 71 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17848 | 0.000 | 0.1161 | No |
| 72 | IFNA17 | interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422] | 18200 | 0.000 | 0.1066 | No |
| 73 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18206 | 0.000 | 0.1065 | No |
| 74 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18909 | 0.000 | 0.0875 | No |
| 75 | DSG3 | desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050] | 18926 | 0.000 | 0.0870 | No |
| 76 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19041 | 0.000 | 0.0839 | No |
| 77 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 19061 | 0.000 | 0.0834 | No |
| 78 | EPS8L3 | EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297] | 19124 | 0.000 | 0.0817 | No |
| 79 | NGF | nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808] | 19262 | 0.000 | 0.0780 | No |
| 80 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19747 | 0.000 | 0.0649 | No |
| 81 | NR1I3 | nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969] | 19916 | 0.000 | 0.0604 | No |
| 82 | KLHDC8A | kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] | 20066 | 0.000 | 0.0564 | No |
| 83 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 20435 | 0.000 | 0.0464 | No |
| 84 | KLK1 | kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] | 20621 | 0.000 | 0.0414 | No |
| 85 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 21123 | 0.000 | 0.0278 | No |
| 86 | INSL5 | insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088] | 21856 | 0.000 | 0.0080 | No |
| 87 | INSL4 | insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087] | 21857 | 0.000 | 0.0080 | No |
| 88 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 21991 | 0.000 | 0.0044 | No |
| 89 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 22888 | 0.000 | -0.0198 | No |
| 90 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808] | 23366 | 0.000 | -0.0327 | No |
| 91 | FOXA1 | forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021] | 23698 | 0.000 | -0.0417 | No |
| 92 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 23702 | 0.000 | -0.0418 | No |
| 93 | TCP10L3 | t-complex 10 like 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:11656] | 23851 | 0.000 | -0.0458 | No |
| 94 | IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824] | 23867 | 0.000 | -0.0462 | No |
| 95 | NPFFR1 | neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425] | 24243 | 0.000 | -0.0563 | No |
| 96 | CST5 | cystatin D [Source:HGNC Symbol;Acc:HGNC:2477] | 24734 | 0.000 | -0.0696 | No |
| 97 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 24798 | 0.000 | -0.0713 | No |
| 98 | PRSS21 | serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485] | 25252 | 0.000 | -0.0835 | No |
| 99 | CAPN9 | calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486] | 25921 | 0.000 | -0.1016 | No |
| 100 | PAGE1 | PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107] | 26523 | 0.000 | -0.1179 | No |
| 101 | MAGEA10 | MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797] | 26529 | 0.000 | -0.1180 | No |
| 102 | ITIH5 | inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449] | 26919 | 0.000 | -0.1285 | No |
| 103 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 27095 | 0.000 | -0.1333 | No |
| 104 | BAAT | bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932] | 27117 | 0.000 | -0.1338 | No |
| 105 | CLEC3B | C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891] | 27478 | -0.000 | -0.1436 | No |
| 106 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 27809 | -0.047 | -0.1518 | No |
| 107 | MDFI | MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967] | 27938 | -0.063 | -0.1544 | No |
| 108 | FCHO1 | FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002] | 28020 | -0.069 | -0.1556 | No |
| 109 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 28148 | -0.087 | -0.1578 | No |
| 110 | GRM2 | glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594] | 28698 | -0.150 | -0.1706 | No |
| 111 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 28769 | -0.159 | -0.1703 | No |
| 112 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 28798 | -0.163 | -0.1687 | No |
| 113 | RPL10P17 | ribosomal protein L10 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52348] | 28884 | -0.176 | -0.1686 | No |
| 114 | ZDHHC8P1 | ZDHHC8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26461] | 28976 | -0.188 | -0.1684 | No |
| 115 | VILL | villin like [Source:HGNC Symbol;Acc:HGNC:30906] | 29154 | -0.207 | -0.1703 | No |
| 116 | AGRP | agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330] | 29287 | -0.222 | -0.1707 | No |
| 117 | EGFL7 | EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594] | 29961 | -0.308 | -0.1846 | No |
| 118 | HHIPL2 | HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842] | 30940 | -0.443 | -0.2048 | No |
| 119 | SEC31B | SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197] | 31511 | -0.532 | -0.2128 | No |
| 120 | GPR35 | G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492] | 31878 | -0.589 | -0.2144 | No |
| 121 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 32781 | -0.788 | -0.2277 | No |
| 122 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 32867 | -0.808 | -0.2186 | No |
| 123 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423] | 33100 | -0.866 | -0.2127 | No |
| 124 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 33727 | -1.039 | -0.2151 | No |
| 125 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 34344 | -1.232 | -0.2144 | No |
| 126 | KIF21B | kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] | 34959 | -1.495 | -0.2100 | No |
| 127 | ECEL1 | endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147] | 35104 | -1.571 | -0.1918 | No |
| 128 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 35200 | -1.625 | -0.1715 | No |
| 129 | KLF3 | Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516] | 35296 | -1.674 | -0.1505 | No |
| 130 | PHLDA3 | pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934] | 35501 | -1.792 | -0.1308 | No |
| 131 | H2AC13 | H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725] | 35693 | -1.922 | -0.1090 | No |
| 132 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 35917 | -2.097 | -0.0855 | No |
| 133 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 36191 | -2.319 | -0.0603 | No |
| 134 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36638 | -2.886 | -0.0318 | No |
| 135 | TREM2 | triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761] | 36765 | -3.127 | 0.0088 | No |
